Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition L von Kleist, W Stahlschmidt, H Bulut, K Gromova, D Puchkov, ... Cell 146 (3), 471-484, 2011 | 586 | 2011 |
Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells MT Howes, M Kirkham, J Riches, K Cortese, PJ Walser, F Simpson, ... Journal of Cell Biology 190 (4), 675-691, 2010 | 331 | 2010 |
Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis A McCluskey, JA Daniel, G Hadzic, N Chau, EL Clayton, A Mariana, ... Traffic 14 (12), 1272-1289, 2013 | 314 | 2013 |
Serine− threonine protein phosphatase inhibitors: Development of potential therapeutic strategies A McCluskey, ATR Sim, JA Sakoff Journal of medicinal chemistry 45 (6), 1151-1175, 2002 | 304 | 2002 |
Activity and thermal stability of lysozyme in alkylammonium formate ionic liquids—influence of cation modification JP Mann, A McCluskey, R Atkin Green Chemistry 11 (6), 785-792, 2009 | 203 | 2009 |
A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells JR Stehn, NK Haass, T Bonello, M Desouza, G Kottyan, H Treutlein, ... Cancer research 73 (16), 5169-5182, 2013 | 202 | 2013 |
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ... Science Translational Medicine 9 (392), eaal3447, 2017 | 199 | 2017 |
‘Green’leaching: recyclable and selective leaching of gold-bearing ore in an ionic liquid JA Whitehead, GA Lawrance, A McCluskey Green Chemistry 6 (7), 313-315, 2004 | 187 | 2004 |
Inhibition of Dynamin Mediated Endocytosis by the DynolesSynthesis and Functional Activity of a Family of Indoles TA Hill, CP Gordon, AB McGeachie, B Venn-Brown, LR Odell, N Chau, ... Journal of medicinal chemistry 52 (12), 3762-3773, 2009 | 179 | 2009 |
Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism CB Harper, S Martin, TH Nguyen, SJ Daniels, NA Lavidis, MR Popoff, ... Journal of Biological Chemistry 286 (41), 35966-35976, 2011 | 169 | 2011 |
Application of 1-alkyl-3-methyl-imidazolium ionic liquids in the oxidative leaching of sulphidic copper, gold and silver ores JA Whitehead, J Zhang, N Pereira, A McCluskey, GA Lawrance Hydrometallurgy 88 (1-4), 109-120, 2007 | 158 | 2007 |
Modified norcantharidins: synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity ME Hart, AR Chamberlin, C Walkom, JA Sakoff, A McCluskey Bioorganic & medicinal chemistry letters 14 (8), 1969-1973, 2004 | 153 | 2004 |
Cantharidin analogues: synthesis and evaluation of growth inhibition in a panel of selected tumour cell lines A McCluskey, SP Ackland, MC Bowyer, ML Baldwin, J Garner, ... Bioorganic chemistry 31 (1), 68-79, 2003 | 150 | 2003 |
The expanding utility of continuous flow hydrogenation PJ Cossar, L Hizartzidis, MI Simone, A McCluskey, CP Gordon Organic & Biomolecular Chemistry 13 (26), 7119-7130, 2015 | 131 | 2015 |
Phenothiazine‐derived antipsychotic drugs inhibit dynamin and clathrin‐mediated endocytosis JA Daniel, N Chau, MK Abdel‐Hamid, L Hu, L von Kleist, A Whiting, ... Traffic 16 (6), 635-654, 2015 | 130 | 2015 |
Endocytosis inhibition in humans to improve responses to ADCC-mediating antibodies HY Chew, PO De Lima, JLG Cruz, B Banushi, G Echejoh, L Hu, ... Cell 180 (5), 895-914. e27, 2020 | 128 | 2020 |
Anhydride modified cantharidin analogues: synthesis, inhibition of protein phosphatases 1 and 2A and anticancer activity A McCluskey, MC Bowyer, E Collins, ATR Sim, JA Sakoff, ML Baldwin Bioorganic & medicinal chemistry letters 10 (15), 1687-1690, 2000 | 128 | 2000 |
Anticancer activity and protein phosphatase 1 and 2A inhibition of a new generation of cantharidin analogues JA Sakoff, SP Ackland, ML Baldwin, MA Keane, A McCluskey Investigational new drugs 20, 1-11, 2002 | 127 | 2002 |
Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A A McCluskey, C Walkom, MC Bowyer, SP Ackland, E Gardiner, JA Sakoff Bioorganic & medicinal chemistry letters 11 (22), 2941-2946, 2001 | 125 | 2001 |
Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation TA Hill, SG Stewart, SP Ackland, J Gilbert, B Sauer, JA Sakoff, ... Bioorganic & medicinal chemistry 15 (18), 6126-6134, 2007 | 124 | 2007 |