Improved formulation of photosensitizer chlorin e6 polyvinylpyrrolidone for fluorescence diagnostic imaging and photodynamic therapy of human cancer WWL Chin, PWS Heng, PSP Thong, R Bhuvaneswari, W Hirt, S Kuenzel, ... European journal of pharmaceutics and biopharmaceutics 69 (3), 1083-1093, 2008 | 126 | 2008 |
A brief literature and patent review of nanosuspensions to a final drug product WWL Chin, J Parmentier, M Widzinski, EH Tan, R Gokhale Journal of Pharmaceutical Sciences 103 (10), 2980-2999, 2014 | 109 | 2014 |
Molecular profiling of angiogenesis in hypericin mediated photodynamic therapy R Bhuvaneswari, YY Gan, SS Lucky, WWL Chin, SM Ali, KC Soo, M Olivo Molecular cancer 7, 1-14, 2008 | 79 | 2008 |
Chlorin e6-polyvinylpyrrolidone as a fluorescent marker for fluorescence diagnosis of human bladder cancer implanted on the chick chorioallantoic membrane model WWL Chin, WKO Lau, R Bhuvaneswari, PWS Heng, M Olivo Cancer letters 245 (1-2), 127-133, 2007 | 78 | 2007 |
Preclinical efficacy studies in investigator brochures: do they enable risk–benefit assessment? S Wieschowski, WWL Chin, C Federico, S Sievers, J Kimmelman, ... PLoS biology 16 (4), e2004879, 2018 | 77 | 2018 |
Fluorescence imaging and phototoxicity effects of new formulation of chlorin e6–polyvinylpyrrolidone WWL Chin, WKO Lau, PWS Heng, R Bhuvaneswari, M Olivo Journal of Photochemistry and Photobiology B: Biology 84 (2), 103-110, 2006 | 75 | 2006 |
The potential application of chlorin e6—polyvinylpyrrolidone formulation in photodynamic therapy WWL Chin, PWS Heng, R Bhuvaneswari, WKO Lau, M Olivo Photochemical & Photobiological Sciences 5, 1031-1037, 2006 | 60 | 2006 |
Clinical application of fluorescence endoscopic imaging using hypericin for the diagnosis of human oral cavity lesions PSP Thong, M Olivo, WWL Chin, R Bhuvaneswari, K Mancer, KC Soo British journal of cancer 101 (9), 1580-1584, 2009 | 59 | 2009 |
Chlorin e6–polyvinylpyrrolidone mediated photosensitization is effective against human non-small cell lung carcinoma compared to small cell lung carcinoma xenografts WWL Chin, PWS Heng, M Olivo BMC pharmacology 7, 1-9, 2007 | 51 | 2007 |
Immune response against angiosarcoma following lower fluence rate clinical photodynamic therapy PSP Thong, M Olivo, KW Kho, R Bhuvaneswari, WWL Chin, KW Ong, ... Journal of Environmental Pathology, Toxicology and Oncology 27 (1), 2008 | 48 | 2008 |
Chlorin e6-polyvinylpyrrolidone mediated photodynamic therapy—A potential bladder sparing option for high risk non-muscle invasive bladder cancer LS Lee, PSP Thong, M Olivo, WWL Chin, B Ramaswamy, KW Kho, PL Lim, ... Photodiagnosis and photodynamic therapy 7 (4), 213-220, 2010 | 45 | 2010 |
Photodynamic diagnosis of a human nasopharyngeal carcinoma xenograft model using the novel Chlorin e6 photosensitizer Fotolon® B Ramaswamy, V Manivasager, WWL Chin, KC Soo, M Olivo International journal of oncology 26 (6), 1501-1506, 2005 | 42 | 2005 |
In-vivo optical detection of cancer using chlorin e6–polyvinylpyrrolidone induced fluorescence imaging and spectroscopy WWL Chin, PSP Thong, R Bhuvaneswari, KC Soo, PWS Heng, M Olivo BMC medical imaging 9, 1-13, 2009 | 40 | 2009 |
Effect of binders on the release rates of direct molded verapamil tablets using twin-screw extruder in melt granulation DCT Tan, WWL Chin, EH Tan, S Hong, W Gu, R Gokhale International journal of pharmaceutics 463 (1), 89-97, 2014 | 36 | 2014 |
Enhanced photodynamic activity of hypericin by penetration enhancer N-methyl pyrrolidone formulations in the chick chorioallantoic membrane model CLL Saw, PWS Heng, WWL Chin, KC Soo, M Olivo Cancer letters 238 (1), 104-110, 2006 | 32 | 2006 |
Perylenequinones in photodynamic therapy: cellular versus vascular response M Olivo, WWL Chin Journal of environmental pathology, toxicology and oncology 25 (1-2), 2006 | 32 | 2006 |
Transport of hypericin across chick chorioallantoic membrane and photodynamic therapy vasculature assessment CLL Saw, M Olivo, WWL Chin, KC Soo, PWS Heng Biological and Pharmaceutical Bulletin 28 (6), 1054-1060, 2005 | 31 | 2005 |
Superiority of N-methyl pyrrolidone over albumin with hypericin for fluorescence diagnosis of human bladder cancer cells implanted in the chick chorioallantoic membrane model CLL Saw, M Olivo, WWL Chin, KC Soo, PWS Heng Journal of Photochemistry and Photobiology B: Biology 86 (3), 207-218, 2007 | 29 | 2007 |
Effect of polyvinylpyrrolidone on the interaction of chlorin e6 with plasma proteins and its subcellular localization WWL Chin, T Praveen, PWS Heng, M Olivo European journal of pharmaceutics and biopharmaceutics 76 (2), 245-252, 2010 | 25 | 2010 |
Evaluation of Hypocrellin B in a human bladder tumor model in experimental photodynamic therapy: biodistribution, light dose and drug-light interval effects W Chin, W Lau, C Cheng, M Olivo International journal of oncology 25 (3), 623-629, 2004 | 25 | 2004 |