A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae A Hammond, R Galizi, K Kyrou, A Simoni, C Siniscalchi, D Katsanos, ... Nature biotechnology 34 (1), 78-83, 2016 | 1378 | 2016 |
A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes K Kyrou, AM Hammond, R Galizi, N Kranjc, A Burt, AK Beaghton, T Nolan, ... Nature biotechnology 36 (11), 1062-1066, 2018 | 806 | 2018 |
The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito AM Hammond, K Kyrou, M Bruttini, A North, R Galizi, X Karlsson, N Kranjc, ... PLoS genetics 13 (10), e1007039, 2017 | 281 | 2017 |
A CRISPR-Cas9 sex-ratio distortion system for genetic control R Galizi, A Hammond, K Kyrou, C Taxiarchi, F Bernardini, SM O’Loughlin, ... Scientific reports 6 (1), 31139, 2016 | 199 | 2016 |
A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae A Simoni, AM Hammond, AK Beaghton, R Galizi, C Taxiarchi, K Kyrou, ... Nature biotechnology 38 (9), 1054-1060, 2020 | 196 | 2020 |
Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance A Hammond, X Karlsson, I Morianou, K Kyrou, A Beaghton, M Gribble, ... PLoS genetics 17 (1), e1009321, 2021 | 125* | 2021 |
Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field A Hammond, P Pollegioni, T Persampieri, A North, R Minuz, A Trusso, ... Nature Communications 12 (1), 4589, 2021 | 87 | 2021 |
Natural infection of C. elegans by an oomycete reveals a new pathogen-specific immune response GA Osman, MK Fasseas, SL Koneru, CL Essmann, K Kyrou, ... Current Biology 28 (4), 640-648. e5, 2018 | 50 | 2018 |
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression C Taxiarchi, A Beaghton, NI Don, K Kyrou, M Gribble, D Shittu, SP Collins, ... Nature Communications 12 (1), 3977, 2021 | 44 | 2021 |
High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation C Taxiarchi, N Kranjc, A Kriezis, K Kyrou, F Bernardini, S Russell, T Nolan, ... Scientific reports 9 (1), 14841, 2019 | 31 | 2019 |
Cross-Species Y Chromosome Function Between Malaria Vectors of the Anopheles gambiae Species Complex F Bernardini, R Galizi, M Wunderlich, C Taxiarchi, N Kranjc, K Kyrou, ... Genetics 207 (2), 729-740, 2017 | 22 | 2017 |
Assessing the acoustic behaviour of Anopheles gambiae (s.l.) dsxF mutants: implications for vector control MP Su, M Georgiades, J Bagi, K Kyrou, A Crisanti, JT Albert Parasites & Vectors 13, 1-9, 2020 | 17 | 2020 |
Driving down malaria transmission with engineered gene drives WT Garrood, P Cuber, K Willis, F Bernardini, NM Page, ... Frontiers in Genetics 13, 891218, 2022 | 8 | 2022 |
Very massive star winds as sources of the short-lived radioactive isotope 26Al S Martinet, G Meynet, D Nandal, S Ekström, C Georgy, L Haemmerlé, ... Astronomy & Astrophysics 664, A181, 2022 | 8 | 2022 |
Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome N Page, C Taxiarchi, D Tonge, J Kuburic, E Chesters, A Kriezis, K Kyrou, ... Communications Biology 6 (1), 850, 2023 | 2 | 2023 |
Population suppression of the malaria vector Anopheles gambiae by gene drive technology: A large-cage indoor study bridging the gap between laboratory and field testing A Hammond, P Pollegioni, T Persampieri, A North, R Minuz, A Trusso, ... | 2 | 2021 |
Siniscalchi c, Katsanos d, Gribble M, Baker d, Marois E, Russell S, et al: A cRISPR-cas9 gene drive system targeting female reproduction in the malaria mosquito vector … A Hammond, R Galizi, K Kyrou, A Simoni Nat Biotechnol 34, 78-83, 2016 | 2 | 2016 |
Y chromosome shredding in Anopheles gambiae: Insight into the cellular dynamics of a novel synthetic sex ratio distorter M Vitale, N Kranjc, J Leigh, K Kyrou, T Courty, L Marston, S Grilli, ... PLoS genetics 20 (6), e1011303, 2024 | | 2024 |
Targeting sex determination for genetic control of the malaria mosquito K Kyrou Imperial College London, 2021 | | 2021 |
Ανάλυση οσμοδεσμευόμενων πρωτεϊνών που εκφράζονται ειδικά στις ωοθήκες του κουνουπιού της ελονοσίας Anopheles gambiae ως πιθανών στόχων για τη μείωση της γονιμότητας θηλυκών … Κ Κύρου | | 2014 |