An atlas of genetic influences on osteoporosis in humans and mice JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, RC Chai, ... Nature genetics 51 (2), 258-266, 2019 | 644 | 2019 |
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption MM McDonald, WH Khoo, PY Ng, Y Xiao, J Zamerli, P Thatcher, W Kyaw, ... Cell 184 (5), 1330-1347. e13, 2021 | 298 | 2021 |
Current trends in the etiology and diagnosis of HPV‐related head and neck cancers RC Chai, D Lambie, M Verma, C Punyadeera Cancer medicine 4 (4), 596-607, 2015 | 158 | 2015 |
A niche-dependent myeloid transcriptome signature defines dormant myeloma cells WH Khoo, G Ledergor, A Weiner, DL Roden, RL Terry, MM McDonald, ... Blood, The Journal of the American Society of Hematology 134 (1), 30-43, 2019 | 118 | 2019 |
The inositol polyphosphate 5-phosphatase PIPP regulates AKT1-dependent breast cancer growth and metastasis LM Ooms, LC Binge, EM Davies, P Rahman, JRW Conway, R Gurung, ... Cancer cell 28 (2), 155-169, 2015 | 113 | 2015 |
Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats M Jüllig, AJR Hickey, CC Chai, GL Skea, MJ Middleditch, S Costa, ... Proteomics 8 (12), 2556-2572, 2008 | 112 | 2008 |
A pilot study to compare the detection of HPV-16 biomarkers in salivary oral rinses with tumour p16INK4a expression in head and neck squamous cell carcinoma … RC Chai, Y Lim, IH Frazer, Y Wan, C Perry, L Jones, D Lambie, ... BMC cancer 16, 1-8, 2016 | 94 | 2016 |
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease SE Youlten, JP Kemp, JG Logan, EJ Ghirardello, CM Sergio, MRG Dack, ... Nature communications 12 (1), 2444, 2021 | 80 | 2021 |
HSP90 inhibitors enhance differentiation and MITF (microphthalmia transcription factor) activity in osteoclast progenitors AGJ van der Kraan, RCC Chai, PP Singh, BJ Lang, J Xu, MT Gillespie, ... Biochemical Journal 451 (2), 235-244, 2013 | 67 | 2013 |
Early organ-specific mitochondrial dysfunction of jejunum and lung found in rats with experimental acute pancreatitis A Mittal, AJR Hickey, CC Chai, BPT Loveday, N Thompson, A Dare, ... HPB 13 (5), 332-341, 2011 | 43 | 2011 |
Impaired ATP turnover and ADP supply depress cardiac mitochondrial respiration and elevate superoxide in nonfailing spontaneously hypertensive rat hearts AJR Hickey, CC Chai, SY Choong, S de Freitas Costa, GL Skea, ... American Journal of Physiology-Cell Physiology 297 (3), C766-C774, 2009 | 43 | 2009 |
Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases J Jurczyluk, MA Munoz, OP Skinner, RC Chai, N Ali, U Palendira, ... Immunology and Cell Biology 94 (10), 994-999, 2016 | 41 | 2016 |
Defective protein prenylation is a diagnostic biomarker of mevalonate kinase deficiency MA Munoz, J Jurczyluk, S Mehr, RC Chai, RJW Arts, A Sheu, C McMahon, ... Journal of allergy and clinical immunology 140 (3), 873-875. e6, 2017 | 33 | 2017 |
Heat stress induces epithelial plasticity and cell migration independent of heat shock factor 1 BJ Lang, L Nguyen, HC Nguyen, JL Vieusseux, RCC Chai, C Christophi, ... Cell Stress and Chaperones 17 (6), 765-778, 2012 | 25 | 2012 |
Molecular stress-inducing compounds increase osteoclast formation in a heat shock factor 1 protein-dependent manner RC Chai, MM Kouspou, BJ Lang, CH Nguyen, AGJ van der Kraan, ... Journal of Biological Chemistry 289 (19), 13602-13614, 2014 | 24 | 2014 |
Histone deacetylase activity mediates acquired resistance towards structurally diverse HSP 90 inhibitors RC Chai, JL Vieusseux, BJ Lang, CH Nguyen, MM Kouspou, KL Britt, ... Molecular Oncology 11 (5), 567-583, 2017 | 22 | 2017 |
Heat-shock factor 1 both positively and negatively affects cellular clonogenic growth depending on p53 status CH Nguyen, BJ Lang, RCC Chai, JL Vieusseux, MM Kouspou, JT Price Biochemical Journal 452 (2), 321-329, 2013 | 17 | 2013 |
An atlas of human and murine genetic influences on osteoporosis JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, R Chai, ... bioRxiv, 338863, 2018 | 14 | 2018 |
Presence of residual beta cells and co-existing islet autoimmunity in the NOD mouse during longstanding diabetes: a combined histochemical and immunohistochemical study S Reddy, RCC Chai, JA Rodrigues, TH Hsu, E Robinson Journal of molecular histology 39, 25-36, 2008 | 13 | 2008 |
Single-cell RNA sequencing: Unravelling the bone one cell at a time RC Chai Current Osteoporosis Reports 20 (5), 356-362, 2022 | 12 | 2022 |