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Ryan C Chai
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An atlas of genetic influences on osteoporosis in humans and mice
JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, RC Chai, ...
Nature genetics 51 (2), 258-266, 2019
6442019
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
MM McDonald, WH Khoo, PY Ng, Y Xiao, J Zamerli, P Thatcher, W Kyaw, ...
Cell 184 (5), 1330-1347. e13, 2021
2982021
Current trends in the etiology and diagnosis of HPV‐related head and neck cancers
RC Chai, D Lambie, M Verma, C Punyadeera
Cancer medicine 4 (4), 596-607, 2015
1582015
A niche-dependent myeloid transcriptome signature defines dormant myeloma cells
WH Khoo, G Ledergor, A Weiner, DL Roden, RL Terry, MM McDonald, ...
Blood, The Journal of the American Society of Hematology 134 (1), 30-43, 2019
1182019
The inositol polyphosphate 5-phosphatase PIPP regulates AKT1-dependent breast cancer growth and metastasis
LM Ooms, LC Binge, EM Davies, P Rahman, JRW Conway, R Gurung, ...
Cancer cell 28 (2), 155-169, 2015
1132015
Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats
M Jüllig, AJR Hickey, CC Chai, GL Skea, MJ Middleditch, S Costa, ...
Proteomics 8 (12), 2556-2572, 2008
1122008
A pilot study to compare the detection of HPV-16 biomarkers in salivary oral rinses with tumour p16INK4a expression in head and neck squamous cell carcinoma …
RC Chai, Y Lim, IH Frazer, Y Wan, C Perry, L Jones, D Lambie, ...
BMC cancer 16, 1-8, 2016
942016
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease
SE Youlten, JP Kemp, JG Logan, EJ Ghirardello, CM Sergio, MRG Dack, ...
Nature communications 12 (1), 2444, 2021
802021
HSP90 inhibitors enhance differentiation and MITF (microphthalmia transcription factor) activity in osteoclast progenitors
AGJ van der Kraan, RCC Chai, PP Singh, BJ Lang, J Xu, MT Gillespie, ...
Biochemical Journal 451 (2), 235-244, 2013
672013
Early organ-specific mitochondrial dysfunction of jejunum and lung found in rats with experimental acute pancreatitis
A Mittal, AJR Hickey, CC Chai, BPT Loveday, N Thompson, A Dare, ...
HPB 13 (5), 332-341, 2011
432011
Impaired ATP turnover and ADP supply depress cardiac mitochondrial respiration and elevate superoxide in nonfailing spontaneously hypertensive rat hearts
AJR Hickey, CC Chai, SY Choong, S de Freitas Costa, GL Skea, ...
American Journal of Physiology-Cell Physiology 297 (3), C766-C774, 2009
432009
Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases
J Jurczyluk, MA Munoz, OP Skinner, RC Chai, N Ali, U Palendira, ...
Immunology and Cell Biology 94 (10), 994-999, 2016
412016
Defective protein prenylation is a diagnostic biomarker of mevalonate kinase deficiency
MA Munoz, J Jurczyluk, S Mehr, RC Chai, RJW Arts, A Sheu, C McMahon, ...
Journal of allergy and clinical immunology 140 (3), 873-875. e6, 2017
332017
Heat stress induces epithelial plasticity and cell migration independent of heat shock factor 1
BJ Lang, L Nguyen, HC Nguyen, JL Vieusseux, RCC Chai, C Christophi, ...
Cell Stress and Chaperones 17 (6), 765-778, 2012
252012
Molecular stress-inducing compounds increase osteoclast formation in a heat shock factor 1 protein-dependent manner
RC Chai, MM Kouspou, BJ Lang, CH Nguyen, AGJ van der Kraan, ...
Journal of Biological Chemistry 289 (19), 13602-13614, 2014
242014
Histone deacetylase activity mediates acquired resistance towards structurally diverse HSP 90 inhibitors
RC Chai, JL Vieusseux, BJ Lang, CH Nguyen, MM Kouspou, KL Britt, ...
Molecular Oncology 11 (5), 567-583, 2017
222017
Heat-shock factor 1 both positively and negatively affects cellular clonogenic growth depending on p53 status
CH Nguyen, BJ Lang, RCC Chai, JL Vieusseux, MM Kouspou, JT Price
Biochemical Journal 452 (2), 321-329, 2013
172013
An atlas of human and murine genetic influences on osteoporosis
JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, R Chai, ...
bioRxiv, 338863, 2018
142018
Presence of residual beta cells and co-existing islet autoimmunity in the NOD mouse during longstanding diabetes: a combined histochemical and immunohistochemical study
S Reddy, RCC Chai, JA Rodrigues, TH Hsu, E Robinson
Journal of molecular histology 39, 25-36, 2008
132008
Single-cell RNA sequencing: Unravelling the bone one cell at a time
RC Chai
Current Osteoporosis Reports 20 (5), 356-362, 2022
122022
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