Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions A Mildner, H Schmidt, M Nitsche, D Merkler, UK Hanisch, M Mack, ... Nature neuroscience 10 (12), 1544-1553, 2007 | 1201 | 2007 |
High-dimensional single-cell mapping of central nervous system immune cells reveals distinct myeloid subsets in health, aging, and disease D Mrdjen, A Pavlovic, FJ Hartmann, B Schreiner, SG Utz, BP Leung, ... Immunity 48 (2), 380-395. e6, 2018 | 915 | 2018 |
A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis I Nikić, D Merkler, C Sorbara, M Brinkoetter, M Kreutzfeldt, FM Bareyre, ... Nature medicine 17 (4), 495-499, 2011 | 807 | 2011 |
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection F Alfei, K Kanev, M Hofmann, M Wu, HE Ghoneim, P Roelli, ... Nature 571 (7764), 265-269, 2019 | 718 | 2019 |
The alarmin interleukin-33 drives protective antiviral CD8+ T cell responses WV Bonilla, A Fröhlich, K Senn, S Kallert, M Fernandez, S Johnson, ... Science 335 (6071), 984-989, 2012 | 492 | 2012 |
Myelin membrane wrapping of CNS axons by PI (3, 4, 5) P3-dependent polarized growth at the inner tongue N Snaidero, W Möbius, T Czopka, LHP Hekking, C Mathisen, D Verkleij, ... Cell 156 (1), 277-290, 2014 | 470 | 2014 |
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system M Prinz, H Schmidt, A Mildner, KP Knobeloch, UK Hanisch, J Raasch, ... Immunity 28 (5), 675-686, 2008 | 443 | 2008 |
Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A D Merkler, GAS Metz, O Raineteau, V Dietz, ME Schwab, K Fouad Journal of Neuroscience 21 (10), 3665-3673, 2001 | 437 | 2001 |
Efficient testing of motor function in spinal cord injured rats GAS Metz, D Merkler, V Dietz, ME Schwab, K Fouad Brain research 883 (2), 165-177, 2000 | 381 | 2000 |
Aggravation of viral hepatitis by platelet-derived serotonin PA Lang, C Contaldo, P Georgiev, AM El-Badry, M Recher, M Kurrer, ... Nature medicine 14 (7), 756-761, 2008 | 278 | 2008 |
A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination D Merkler, T Ernsting, M Kerschensteiner, W Brück, C Stadelmann Brain 129 (8), 1972-1983, 2006 | 256 | 2006 |
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity C Fecher, L Trovò, SA Müller, N Snaidero, J Wettmarshausen, S Heink, ... Nature neuroscience 22 (10), 1731-1742, 2019 | 235 | 2019 |
TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis B Schattling, K Steinbach, E Thies, M Kruse, A Menigoz, F Ufer, ... Nature medicine 18 (12), 1805-1811, 2012 | 223 | 2012 |
Functional gut microbiota remodeling contributes to the caloric restriction-induced metabolic improvements S Fabbiano, N Suárez-Zamorano, C Chevalier, V Lazarević, S Kieser, ... Cell metabolism 28 (6), 907-921. e7, 2018 | 216 | 2018 |
Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection K Steinbach, I Vincenti, M Kreutzfeldt, N Page, A Muschaweckh, I Wagner, ... Journal of Experimental Medicine 213 (8), 1571-1587, 2016 | 209 | 2016 |
Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis D Merkler, K Maier, C Stadelmann, H Ehrenreich, M Bähr, R Diem Cell Death & Differentiation 11 (2), S181-S192, 2004 | 202 | 2004 |
USP 18 lack in microglia causes destructive interferonopathy of the mouse brain T Goldmann, N Zeller, J Raasch, K Kierdorf, K Frenzel, L Ketscher, ... The EMBO journal 34 (12), 1612-1629, 2015 | 198 | 2015 |
Pervasive axonal transport deficits in multiple sclerosis models CD Sorbara, NE Wagner, A Ladwig, I Nikić, D Merkler, T Kleele, ... Neuron 84 (6), 1183-1190, 2014 | 188 | 2014 |
The immune system bridges the gut microbiota with systemic energy homeostasis: focus on TLRs, mucosal barrier, and SCFAs M Spiljar, D Merkler, M Trajkovski Frontiers in immunology 8, 1353, 2017 | 182 | 2017 |
Effects of commissural de-and remyelination on motor skill behaviour in the cuprizone mouse model of multiple sclerosis D Liebetanz, D Merkler Experimental neurology 202 (1), 217-224, 2006 | 182 | 2006 |