| Memory B cells activate brain-homing, autoreactive CD4+ T cells in multiple sclerosis I Jelcic, F Al Nimer, J Wang, V Lentsch, R Planas, I Jelcic, A Madjovski, ... Cell 175 (1), 85-100. e23, 2018 | 454 | 2018 |
| A randomized double-blind placebo-controlled phase II trial of dendritic cell vaccine ICT-107 in newly diagnosed patients with glioblastoma PY Wen, DA Reardon, TS Armstrong, S Phuphanich, RD Aiken, ... Clinical Cancer Research 25 (19), 5799-5807, 2019 | 222 | 2019 |
| Combinatorial libraries as a tool for the discovery of novel, broad-spectrum antibacterial agents targeting the ESKAPE pathogens R Fleeman, TM LaVoi, RG Santos, A Morales, A Nefzi, GS Welmaker, ... Journal of medicinal chemistry 58 (8), 3340-3355, 2015 | 100 | 2015 |
| Structure–activity relationships of benzimidazole derivatives as antiparasitic agents: dual activity-difference (DAD) maps J Pérez-Villanueva, R Santos, A Hernández-Campos, MA Giulianotti, ... MedChemComm 2 (1), 44-49, 2011 | 99 | 2011 |
| GDP-l-fucose synthase is a CD4+ T cell–specific autoantigen in DRB3*02:02 patients with multiple sclerosis R Planas, R Santos, P Tomas-Ojer, C Cruciani, A Lutterotti, W Faigle, ... Science translational medicine 10 (462), eaat4301, 2018 | 96 | 2018 |
| Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease MT Falta, C Pinilla, DG Mack, AN Tinega, F Crawford, M Giulianotti, ... The Journal of experimental medicine 210 (7), 1403, 2013 | 78 | 2013 |
| Towards a systematic characterization of the antiprotozoal activity landscape of benzimidazole derivatives J Pérez-Villanueva, R Santos, A Hernández-Campos, MA Giulianotti, ... Bioorganic & medicinal chemistry 18 (21), 7380-7391, 2010 | 76 | 2010 |
| Consensus models of activity landscapes with multiple chemical, conformer, and property representations AB Yongye, K Byler, R Santos, K Martínez-Mayorga, GM Maggiora, ... Journal of chemical information and modeling 51 (6), 1259-1270, 2011 | 69 | 2011 |
| Identification of a novel polyamine scaffold with potent efflux pump inhibition activity toward multi-drug resistant bacterial pathogens RM Fleeman, G Debevec, K Antonen, JL Adams, RG Santos, ... Frontiers in microbiology 9, 1301, 2018 | 44 | 2018 |
| Cytokine production but lack of proliferation in peripheral blood mononuclear cells from chronic Chagas' disease cardiomyopathy patients in response to T. cruzi ribosomal P … SA Longhi, A Atienza, G Perez Prados, A Buying, V Balouz, CA Buscaglia, ... PLoS neglected tropical diseases 8 (6), e2906, 2014 | 42 | 2014 |
| CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope SA Greaves, A Ravindran, RG Santos, L Chen, MT Falta, Y Wang, ... Journal of Experimental Medicine 218 (10), e20210785, 2021 | 41 | 2021 |
| Improvement of IFNγ ELISPOT performance following overnight resting of frozen PBMC samples confirmed through rigorous statistical analysis R Santos, A Buying, N Sabri, J Yu, A Gringeri, J Bender, S Janetzki, ... Cells 4 (1), 1-18, 2014 | 41 | 2014 |
| Scaffold ranking and positional scanning utilized in the discovery of nAChR-selective compounds suitable for optimization studies J Wu, Y Zhang, LE Maida, RG Santos, GS Welmaker, TM LaVoi, A Nefzi, ... Journal of medicinal chemistry 56 (24), 10103-10117, 2013 | 41 | 2013 |
| Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries C Pinilla, BS Edwards, JR Appel, T Yates-Gibbins, MA Giulianotti, ... Molecular Pharmacology 84 (3), 314-324, 2013 | 38 | 2013 |
| Characterization of a comprehensive flavor database K Martínez‐Mayorga, TL Peppard, AB Yongye, R Santos, M Giulianotti, ... Journal of chemometrics 25 (10), 550-560, 2011 | 38 | 2011 |
| Discovery of an enzyme and substrate selective inhibitor of ADAM10 using an exosite-binding glycosylated substrate F Madoux, D Dreymuller, JP Pettiloud, R Santos, C Becker-Pauly, ... Scientific reports 6 (1), 11, 2016 | 37 | 2016 |
| Use and implications of the harmonic mean model on mixtures for basic research and drug discovery RG Santos, MA Giulianotti, CT Dooley, C Pinilla, JR Appel, RA Houghten ACS combinatorial science 13 (3), 337-344, 2011 | 31 | 2011 |
| Identification of protein palmitoylation inhibitors from a scaffold ranking library L D Hamel, B J Lenhart, D A Mitchell, R G Santos, M A Giulianotti, ... Combinatorial chemistry & high throughput screening 19 (4), 262-274, 2016 | 30 | 2016 |
| Identification of tetrapeptides from a mixture based positional scanning library that can restore nM full agonist function of the L106P, I69T, I102S, A219V, C271Y, and C271R … EM Haslach, H Huang, M Dirain, G Debevec, P Geer, RG Santos, ... Journal of medicinal chemistry 57 (11), 4615-4628, 2014 | 30 | 2014 |
| Rapid scanning structure–activity relationships in combinatorial data sets: identification of activity switches JL Medina-Franco, BS Edwards, C Pinilla, JR Appel, MA Giulianotti, ... Journal of chemical information and modeling 53 (6), 1475-1485, 2013 | 29 | 2013 |
