Substrate modulus directs neural stem cell behavior K Saha, AJ Keung, EF Irwin, Y Li, L Little, DV Schaffer, KE Healy Biophysical journal 95 (9), 4426-4438, 2008 | 1291 | 2008 |
A designer AAV variant permits efficient retrograde access to projection neurons DGR Tervo, BY Hwang, S Viswanathan, T Gaj, M Lavzin, KD Ritola, ... Neuron 92 (2), 372-382, 2016 | 1128 | 2016 |
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo K Lai, BK Kaspar, FH Gage, DV Schaffer Nature neuroscience 6 (1), 21-27, 2003 | 1049 | 2003 |
Engineering adeno-associated viruses for clinical gene therapy MA Kotterman, DV Schaffer Nature Reviews Genetics 15 (7), 445-451, 2014 | 893 | 2014 |
In vivo–directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous D Dalkara, LC Byrne, RR Klimczak, M Visel, L Yin, WH Merigan, ... Science translational medicine 5 (189), 189ra76-189ra76, 2013 | 764 | 2013 |
The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells A Banerjee, M Arha, S Choudhary, RS Ashton, SR Bhatia, DV Schaffer, ... Biomaterials 30 (27), 4695-4699, 2009 | 750 | 2009 |
Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity LS Weinberger, JC Burnett, JE Toettcher, AP Arkin, DV Schaffer Cell 122 (2), 169-182, 2005 | 730 | 2005 |
Vector unpacking as a potential barrier for receptor‐mediated polyplex gene delivery DV Schaffer, NA Fidelman, N Dan, DA Lauffenburger Biotechnology and bioengineering 67 (5), 598-606, 2000 | 672 | 2000 |
Directed evolution of adeno-associated virus yields enhanced gene delivery vectors N Maheshri, JT Koerber, BK Kaspar, DV Schaffer Nature biotechnology 24 (2), 198-204, 2006 | 668 | 2006 |
The AAV vector toolkit: poised at the clinical crossroads A Asokan, DV Schaffer, RJ Samulski Molecular Therapy 20 (4), 699-708, 2012 | 559 | 2012 |
Biophysical regulation of epigenetic state and cell reprogramming TL Downing, J Soto, C Morez, T Houssin, A Fritz, F Yuan, J Chu, S Patel, ... Nature materials 12 (12), 1154-1162, 2013 | 508 | 2013 |
Viral vectors for gene therapy: translational and clinical outlook MA Kotterman, TW Chalberg, DV Schaffer Annual review of biomedical engineering 17, 63-89, 2015 | 503 | 2015 |
Optogenetic protein clustering and signaling activation in mammalian cells LJ Bugaj, AT Choksi, CK Mesuda, RS Kane, DV Schaffer Nature methods 10 (3), 249-252, 2013 | 497 | 2013 |
PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation J Peltier, A O'Neill, DV Schaffer Developmental neurobiology 67 (10), 1348-1361, 2007 | 495 | 2007 |
Single-cell western blotting AJ Hughes, DP Spelke, Z Xu, CC Kang, DV Schaffer, AE Herr Nature methods 11 (7), 749-755, 2014 | 468 | 2014 |
Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous D Dalkara, KD Kolstad, N Caporale, M Visel, RR Klimczak, DV Schaffer, ... Molecular Therapy 17 (12), 2096-2102, 2009 | 378 | 2009 |
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation Y Lei, DV Schaffer Proceedings of the National Academy of Sciences 110 (52), E5039-E5048, 2013 | 349 | 2013 |
X‐space MPI: magnetic nanoparticles for safe medical imaging PW Goodwill, EU Saritas, LR Croft, TN Kim, KM Krishnan, DV Schaffer, ... Advanced materials 24 (28), 3870-3877, 2012 | 342 | 2012 |
Quantitative magnetic particle imaging monitors the transplantation, biodistribution, and clearance of stem cells in vivo B Zheng, MP von See, E Yu, B Gunel, K Lu, T Vazin, DV Schaffer, ... Theranostics 6 (3), 291, 2016 | 330 | 2016 |
Transforming growth factor-β and notch signaling mediate stem cell differentiation into smooth muscle cells K Kurpinski, H Lam, J Chu, A Wang, A Kim, E Tsay, S Agrawal, ... Stem cells 28 (4), 734-742, 2010 | 325 | 2010 |