关注
Alexander Kertser
Alexander Kertser
Immunobrain Checkpoint Ltd.
在 immunobrain.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Aging-induced type I interferon response at the choroid plexus negatively affects brain function
K Baruch, A Deczkowska, E David, JM Castellano, O Miller, A Kertser, ...
Science 346 (6205), 89-93, 2014
5892014
Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer’s disease pathology
K Baruch, N Rosenzweig, A Kertser, A Deczkowska, AM Sharif, A Spinrad, ...
Nature communications 6 (1), 7967, 2015
4472015
PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease
K Baruch, A Deczkowska, N Rosenzweig, A Tsitsou-Kampeli, AM Sharif, ...
Nature medicine 22 (2), 135-137, 2016
3762016
IFN-γ-dependent activation of the brain’s choroid plexus for CNS immune surveillance and repair
G Kunis, K Baruch, N Rosenzweig, A Kertser, O Miller, T Berkutzki, ...
Brain 136 (11), 3427-3440, 2013
3372013
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
A Deczkowska, O Matcovitch-Natan, A Tsitsou-Kampeli, S Ben-Hamo, ...
Nature communications 8 (1), 717, 2017
2132017
Cerebral nitric oxide represses choroid plexus NF κB‐dependent gateway activity for leukocyte trafficking
K Baruch, A Kertser, Z Porat, M Schwartz
The EMBO journal 34 (13), 1816-1828, 2015
942015
Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress
H Ben-Yehuda, O Matcovitch-Natan, A Kertser, A Spinrad, M Prinz, I Amit, ...
Molecular psychiatry 25 (5), 1050-1067, 2020
562020
Corticosteroid signaling at the brain-immune interface impedes coping with severe psychological stress
A Kertser, K Baruch, A Deczkowska, A Weiner, T Croese, M Kenigsbuch, ...
Science Advances 5 (5), eaav4111, 2019
352019
Severe psychological stress impairs choroid plexus gateway activity for leukocyte trafficking
A Kertser, K Baruch, I Cooper, M Schwartz
Brain, Behavior, and Immunity 66, e10, 2017
22017
IBC‐Ab002, an anti‐PD‐L1 monoclonal antibody tailored for treating Alzheimer’s disease: Nonhuman/Lead optimization studies
K Baruch, A Kertser, O Matalon, O Forsht, S Braiman, E Shochat, C David, ...
Alzheimer's & Dementia 16, e042978, 2020
12020
Targeting low levels of MIF expression as a potential therapeutic strategy for ALS
L Alfahel, T Gschwendtberger, V Kozareva, L Dumas, R Gibbs, A Kertser, ...
Cell Reports Medicine 5 (5), 2024
2024
PD‐L1 blockade therapeutic effect in Tau P301S (line PS19) mouse model of tauopathy
K Baruch, A Kertser, S Medina, M Arad, E Yoles, M Schwartz
Alzheimer's & Dementia 19, e075611, 2023
2023
IBC‐Ab002 Fc modifications for fast clearance are associated with advantageous safety profile
A Kertser, K Baruch, E Yoles, M Schwartz
Alzheimer's & Dementia 19, e075622, 2023
2023
Maternal immune activation adversely affects the offspring's microglia via Type-I interferon signaling
H Ben-Yehuda, O Matcovitch-Natan, A Kertser, A Spinrad, I Amit, ...
IBRO Reports 6, S554, 2019
2019
Systemic immunity protects the mind: Can immune checkpoint blockade combat Alzheimer's disease?
A Kertser, M Schwartz
Neurology, Psychiatry and Brain Research 29, 13, 2018
2018
S42. Maternal Immune Activation Downregulates Microglia Proliferation in the Developing Brain
H Ben-Yehuda, O Matcovitch-Natan, A Kertser, A Spinrad, I Amit, ...
Biological Psychiatry 83 (9), S363, 2018
2018
Regulation of the blood-cerebrospinal fluid barrier as a gateway for leukocyte trafficking in physiology and pathology
A Kertser
PQDT-Global, 2018
2018
Abstract# 1715 Transiently breaking immune tolerance by targeting Foxp3+ CD4+ regulatory T cells mitigates Alzheimer’s disease pathology
N Rosenzweig, K Baruch, A Kertser, A Deczkowska, M Schwartz
Brain, Behavior, and Immunity 57, e4-e5, 2016
2016
Aging-induced immunological signature of the brain's choroid plexus negatively regulates neurogenesis and cognitive function
A Deczkowska, K Baruch, E David, JM Castellano, O Miller, A Kertser, ...
Journal of Neuroimmunology 275 (1), 124, 2014
2014
A two-signal model for non-pathological activation of the choroid plexus epithelium for trafficking to the central nervous system
K Baruch, G Kunis, N Rosenzweig, A Kertser, M Schwartz
JOURNAL OF MOLECULAR NEUROSCIENCE 51, S18-S18, 2013
2013
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