Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury R Bertini, M Allegretti, C Bizzarri, A Moriconi, M Locati, G Zampella, ... Proceedings of the National Academy of Sciences 101 (32), 11791-11796, 2004 | 383 | 2004 |
2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors M Allegretti, R Bertini, MC Cesta, C Bizzarri, R Di Bitondo, V Di Cioccio, ... Journal of medicinal chemistry 48 (13), 4312-4331, 2005 | 142 | 2005 |
Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2 A Moriconi, MC Cesta, MN Cervellera, A Aramini, S Coniglio, S Colagioia, ... Journal of medicinal chemistry 50 (17), 3984-4002, 2007 | 112 | 2007 |
The role of interleukin-8 in lung inflammation and injury: implications for the management of COVID-19 and hyperinflammatory acute respiratory distress syndrome MC Cesta, M Zippoli, C Marsiglia, EM Gavioli, F Mantelli, M Allegretti, ... Frontiers in pharmacology 12, 808797, 2022 | 92 | 2022 |
Current status of chemokine receptor inhibitors in development M Allegretti, MC Cesta, A Garin, AEI Proudfoot Immunology letters 145 (1-2), 68-78, 2012 | 78 | 2012 |
Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non‐competitive allosteric inhibitor R Bertini, LS Barcelos, AR Beccari, B Cavalieri, A Moriconi, C Bizzarri, ... British journal of pharmacology 165 (2), 436-454, 2012 | 78 | 2012 |
A modified palladium catalysed reductive amination procedure V Berdini, MC Cesta, R Curti, G D'Anniballe, N Di Bello, G Nano, ... Tetrahedron 58 (28), 5669-5674, 2002 | 57 | 2002 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach L Aureli, G Cruciani, MC Cesta, R Anacardio, L De Simone, A Moriconi Journal of medicinal chemistry 48 (7), 2469-2479, 2005 | 54 | 2005 |
One-pot, new stereoselective synthesis of endo-tropanamine M Allegretti, V Berdini, MC Cesta, R Curti, L Nicolini, A Topai Tetrahedron Letters 42 (25), 4257-4259, 2001 | 51 | 2001 |
A Practical Synthesis of 7-Azaindolylcarboxy-e ndo-tropanamide (DF 1012) M Allegretti, R Anacardio, MC Cesta, R Curti, M Mantovanini, G Nano, ... Organic process research & development 7 (2), 209-213, 2003 | 49 | 2003 |
Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection M Allegretti, MC Cesta, M Zippoli, A Beccari, C Talarico, F Mantelli, ... Cell Death & Differentiation 29 (1), 156-166, 2022 | 42 | 2022 |
Targeting FR-expressing cells in ovarian cancer with Fab-functionalized nanoparticles: a full study to provide the proof of principle from in vitro to in vivo A Quarta, D Bernareggi, F Benigni, E Luison, G Nano, S Nitti, MC Cesta, ... Nanoscale 7 (6), 2336-2351, 2015 | 35 | 2015 |
Supercritical fluids processing: preparation of protein microparticles and their stablilisation M Gentile, C Di Palma, MC Cesta US Patent 7,250,152, 2007 | 35 | 2007 |
Allosteric modulation of chemoattractant receptors M Allegretti, MC Cesta, M Locati Frontiers in Immunology 7, 191578, 2016 | 33 | 2016 |
Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis MC Cesta, M Zippoli, C Marsiglia, EM Gavioli, G Cremonesi, A Khan, ... European Journal of Immunology 53 (1), 2250010, 2023 | 32 | 2023 |
Quaternary ammonium salts of omega-aminoalkylamides of r-2-aryl-propionic acids and pharmaceutical compositions containing them M Allegretti, R Bertini, C Bizzarri, MC Cesta US Patent 7,026,510, 2006 | 24 | 2006 |
Sulfonic acids, their derivatives and pharmaceutical compositions containing them M Allegretti, A Aramini, MC Cesta, R Bertini, C Bizzarri, F Colotta US Patent 7,737,139, 2010 | 22 | 2010 |
Emerging role of C5 complement pathway in peripheral neuropathies: Current treatments and future perspectives C Giorgio, M Zippoli, P Cocchiaro, V Castelli, G Varrassi, A Aramini, ... Biomedicines 9 (4), 399, 2021 | 20 | 2021 |
Synthesis and structure-activity relationships of new acetylcholinesterase inhibitors: Morpholinoalkylcarbamoyloxyeseroline derivatives MA Alisi, M Brufani, L Filocamo, G Gostoli, E Licandro, MC Cesta, ... Bioorganic & Medicinal Chemistry Letters 5 (18), 2077-2080, 1995 | 18 | 1995 |
(R)-arylalkylamino derivatives and pharmaceutical compositions containing them M Allegretti, A Moriconi, A Aramini, MC Cesta, A Beccari, R Bertini US Patent 8,026,367, 2011 | 16 | 2011 |