Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities S Heinz, C Benner, N Spann, E Bertolino, YC Lin, P Laslo, JX Cheng, ... Molecular cell 38 (4), 576-589, 2010 | 11521 | 2010 |
Requirement of transcription factor PU. 1 in the development of multiple hematopoietic lineages EW Scott, MC Simon, J Anastasi, H Singh Science 265 (5178), 1573-1577, 1994 | 1920 | 1994 |
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes H Singh, R Sen, D Baltimore, PA Sharp Nature 319 (6049), 154, 1986 | 1252 | 1986 |
Regulation of B lymphocyte and macrophage development by graded expression of PU. 1 RP DeKoter, H Singh Science 288 (5470), 1439-1441, 2000 | 928 | 2000 |
Transcriptional repression mediated by repositioning of genes to the nuclear lamina KL Reddy, JM Zullo, E Bertolino, H Singh Nature 452 (7184), 243, 2008 | 913 | 2008 |
Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development ST Kosak, JA Skok, KL Medina, R Riblet, MM Le Beau, AG Fisher, ... Science 296 (5565), 158-162, 2002 | 848 | 2002 |
Molecular cloning of an enhancer binding protein: isolation by screening of an expression library with a recognition site DNA H Singh, JH LeBowitz, AS Baldwin Jr, PA Sharp Cell 52 (3), 415-423, 1988 | 779 | 1988 |
Multilineage transcriptional priming and determination of alternate hematopoietic cell fates P Laslo, CJ Spooner, A Warmflash, DW Lancki, HJ Lee, R Sciammas, ... Cell 126 (4), 755-766, 2006 | 761 | 2006 |
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes LM Staudt, H Singh, R Sen, T Wirth, PA Sharp, D Baltimore Nature 323 (6089), 640, 1986 | 738 | 1986 |
Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation R Sciammas, AL Shaffer, JH Schatz, H Zhao, LM Staudt, H Singh Immunity 25 (2), 225-236, 2006 | 676 | 2006 |
Pip, a novel IRF family member, is a lymphoid-specific, PU. 1-dependent transcriptional activator. CF Eisenbeis, H Singh, U Storb Genes & development 9 (11), 1377-1387, 1995 | 564 | 1995 |
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner V Ramirez-Carrozzi, A Sambandam, E Luis, Z Lin, S Jeet, J Lesch, ... Nature immunology 12 (12), 1159, 2011 | 506 | 2011 |
IFN regulatory factor-4 and-8 govern dendritic cell subset development and their functional diversity T Tamura, P Tailor, K Yamaoka, HJ Kong, H Tsujimura, JJ O’Shea, ... The Journal of Immunology 174 (5), 2573-2581, 2005 | 503 | 2005 |
Single-cell analysis of mixed-lineage states leading to a binary cell fate choice A Olsson, M Venkatasubramanian, VK Chaudhri, BJ Aronow, ... Nature 537 (7622), 698, 2016 | 502 | 2016 |
Regulation of macrophage and neutrophil cell fates by the PU. 1: C/EBPα ratio and granulocyte colony-stimulating factor R Dahl, JC Walsh, D Lancki, P Laslo, SR Iyer, H Singh, MC Simon Nature immunology 4 (10), 1029, 2003 | 496 | 2003 |
DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina JM Zullo, IA Demarco, R Piqué-Regi, DJ Gaffney, CB Epstein, CJ Spooner, ... Cell 149 (7), 1474-1487, 2012 | 491 | 2012 |
Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4 K Ochiai, M Maienschein-Cline, G Simonetti, J Chen, R Rosenthal, ... Immunity 38 (5), 918-929, 2013 | 481 | 2013 |
Compensatory dendritic cell development mediated by BATF–IRF interactions R Tussiwand, WL Lee, TL Murphy, M Mashayekhi, KC Wumesh, ... Nature 490 (7421), 502, 2012 | 452 | 2012 |
PU. 1 regulates expression of the interleukin-7 receptor in lymphoid progenitors RP DeKoter, HJ Lee, H Singh Immunity 16 (2), 297-309, 2002 | 429 | 2002 |
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression J Rengarajan, KA Mowen, KD McBride, ED Smith, H Singh, LH Glimcher Journal of Experimental Medicine 195 (8), 1003-1012, 2002 | 417 | 2002 |