Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages JA Maddry, RC Reynolds, JA Secrist, JA Montgomery, PA Crooks US Patent 5,561,225, 1996 | 624 | 1996 |
The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L. DR Worthen, OA Ghosheh, PA Crooks Anticancer research 18 (3A), 1527-1532, 1998 | 612 | 1998 |
High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.) OA Ghosheh, AA Houdi, PA Crooks Journal of pharmaceutical and biomedical analysis 19 (5), 757-762, 1999 | 575 | 1999 |
An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells ML Guzman, RM Rossi, S Neelakantan, X Li, CA Corbett, DC Hassane, ... Blood, The Journal of the American Society of Hematology 110 (13), 4427-4435, 2007 | 514 | 2007 |
Means to achieve sustained release of synergistic drugs by conjugation P Ashton, PA Crooks, T Cynkowski, G Cynkowska, H Guo US Patent 6,051,576, 2000 | 504 | 2000 |
A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse LP Dwoskin, PA Crooks Biochemical pharmacology 63 (2), 89-98, 2002 | 287 | 2002 |
Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes HU Gali-Muhtasib, WG Abou Kheir, LA Kheir, N Darwiche, PA Crooks Anti-cancer drugs 15 (4), 389-399, 2004 | 258 | 2004 |
The NF-κB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target S Hewamana, S Alghazal, TT Lin, M Clement, C Jenkins, ML Guzman, ... Blood, The Journal of the American Society of Hematology 111 (9), 4681-4689, 2008 | 226 | 2008 |
Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-κB inhibitor, DMAPT (LC-1) S Neelakantan, S Nasim, ML Guzman, CT Jordan, PA Crooks Bioorganic & medicinal chemistry letters 19 (15), 4346-4349, 2009 | 218 | 2009 |
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells S Pei, M Minhajuddin, KP Callahan, M Balys, JM Ashton, SJ Neering, ... Journal of Biological Chemistry 288 (47), 33542-33558, 2013 | 217 | 2013 |
Lobeline and nicotine evoke [3H] overflow from rat striatal slices preloaded with [3H] dopamine: differential inhibition of synaptosomal and vesicular [3H] dopamine uptake L Teng, PA Crooks, PK Sonsalla, LP Dwoskin Journal of Pharmacology and Experimental Therapeutics 280 (3), 1432-1444, 1997 | 170 | 1997 |
Competitive neuronal nicotinic receptor antagonists: a new direction for drug discovery LP Dwoskin, PA Crooks Journal of Pharmacology and Experimental Therapeutics 298 (2), 395-402, 2001 | 165 | 2001 |
A NADPH oxidase–dependent redox signaling pathway mediates the selective radiosensitization effect of parthenolide in prostate cancer cells Y Sun, DK St. Clair, Y Xu, PA Crooks, WH St. Clair Cancer research 70 (7), 2880-2890, 2010 | 164 | 2010 |
Vesicular monoamine transporter 2: role as a novel target for drug development G Zheng, LP Dwoskin, PA Crooks The AAPS journal 8, E682-E692, 2006 | 161 | 2006 |
Stereochemical course of the transmethylation catalyzed by catechol O-methyltransferase. RW Woodard, MD Tsai, HG Floss, PA Crooks, JK Coward Journal of Biological Chemistry 255 (19), 9124-9127, 1980 | 160 | 1980 |
Lobeline attenuates d-methamphetamine self-administration in rats SB Harrod, LP Dwoskin, PA Crooks, JE Klebaur, MT Bardo Journal of Pharmacology and Experimental Therapeutics 298 (1), 172-179, 2001 | 154 | 2001 |
(S)-(−)-Cotinine, the major brain metabolite of nicotine, stimulates nicotinic receptors to evoke [3H] dopamine release from rat striatal slices in a calcium-dependent manner LP Dwoskin, L Teng, ST Buxton, PA Crooks Journal of pharmacology and experimental therapeutics 288 (3), 905-911, 1999 | 153 | 1999 |
Nornicotine is self-administered intravenously by rats MT Bardo, TA Green, PA Crooks, LP Dwoskin Psychopharmacology 146, 290-296, 1999 | 151 | 1999 |
Lobeline Displaces [3H]Dihydrotetrabenazine Binding and Releases [3H]Dopamine from Rat Striatal Synaptic Vesicles: Comparison with d‐Amphetamine LH Teng, PA Crooks, LP Dwoskin Journal of neurochemistry 71 (1), 258-265, 1998 | 143 | 1998 |
Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking PA Crooks, LP Dwoskin Biochemical pharmacology 54 (7), 743-753, 1997 | 143 | 1997 |