Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib TF Chu, MA Rupnick, R Kerkela, SM Dallabrida, D Zurakowski, L Nguyen, ... The Lancet 370 (9604), 2011-2019, 2007 | 1236 | 2007 |
Ca2+ Influx–Induced Sarcoplasmic Reticulum Ca2+ Overload Causes Mitochondrial-Dependent Apoptosis in Ventricular Myocytes X Chen, X Zhang, H Kubo, DM Harris, GD Mills, J Moyer, R Berretta, ... Circulation research 97 (10), 1009-1017, 2005 | 282 | 2005 |
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes JS Martini, P Raake, LE Vinge, BR DeGeorge Jr, JK Chuprun, DM Harris, ... Proceedings of the National Academy of Sciences 105 (34), 12457-12462, 2008 | 258 | 2008 |
Level of G protein–coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro-and anti-apoptotic mechanisms H Brinks, M Boucher, E Gao, JK Chuprun, S Pesant, PW Raake, ... Circulation research 107 (9), 1140-1149, 2010 | 158 | 2010 |
Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties X Chen, RM Wilson, H Kubo, RM Berretta, DM Harris, X Zhang, N Jaleel, ... Circulation research 100 (4), 536-544, 2007 | 145 | 2007 |
Calcium influx through Cav1. 2 is a proximal signal for pathological cardiomyocyte hypertrophy X Chen, H Nakayama, X Zhang, X Ai, DM Harris, M Tang, H Zhang, ... Journal of molecular and cellular cardiology 50 (3), 460-470, 2011 | 136 | 2011 |
Glycogen synthase kinase-3β regulates post–myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo KC Woulfe, E Gao, H Lal, D Harris, Q Fan, R Vagnozzi, M DeCaul, ... Circulation research 106 (10), 1635-1645, 2010 | 135 | 2010 |
Faculty and second-year medical student perceptions of active learning in an integrated curriculum A Tsang, DM Harris Advances in physiology education 40 (4), 446-453, 2016 | 113 | 2016 |
Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress BR DeGeorge Jr, E Gao, M Boucher, LE Vinge, JS Martini, PW Raake, ... Circulation 117 (11), 1378-1387, 2008 | 111 | 2008 |
GPCR signalling in hypertension: role of GRKs DM Harris, HI Cohn, S Pesant, AD Eckhart Clinical Science 115 (3), 79-89, 2008 | 96 | 2008 |
Alterations in Early Action Potential Repolarization Causes Localized Failure of Sarcoplasmic Reticulum Ca2+ Release DM Harris, GD Mills, X Chen, H Kubo, RM Berretta, VS Votaw, LF Santana, ... Circulation research 96 (5), 543-550, 2005 | 95 | 2005 |
Vascular smooth muscle overexpression of G protein–coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on GI-mediated signaling JR Keys, RH Zhou, DM Harris, CA Druckman, AD Eckhart Circulation 112 (8), 1145-1153, 2005 | 73 | 2005 |
Increasing cardiac contractility after myocardial infarction exacerbates cardiac injury and pump dysfunction H Zhang, X Chen, E Gao, SM MacDonnell, W Wang, M Kolpakov, ... Circulation research 107 (6), 800-809, 2010 | 65 | 2010 |
Using a high-fidelity patient simulator with first-year medical students to facilitate learning of cardiovascular function curves DM Harris, K Ryan, C Rabuck Advances in physiology education 36 (3), 213-219, 2012 | 59 | 2012 |
Inhibition of vascular smooth muscle G protein-coupled receptor kinase 2 enhances α1D-adrenergic receptor constriction HI Cohn, DM Harris, S Pesant, M Pfeiffer, RH Zhou, WJ Koch, ... American Journal of Physiology-Heart and Circulatory Physiology 295 (4 …, 2008 | 59 | 2008 |
G protein–coupled receptor kinase 2 expression and activity are associated with blood pressure in black Americans HI Cohn, Y Xi, S Pesant, DM Harris, T Hyslop, B Falkner, AD Eckhart Hypertension 54 (1), 71-76, 2009 | 57 | 2009 |
Endothelial S100A1 modulates vascular function via nitric oxide ST Pleger, DM Harris, C Shan, LE Vinge, JK Chuprun, B Berzins, ... Circulation research 102 (7), 786-794, 2008 | 46 | 2008 |
Reduced effects of BAY K 8644 on L-type Ca2+ current in failing human cardiac myocytes are related to abnormal adrenergic regulation X Chen, X Zhang, DM Harris, V Piacentino III, RM Berretta, KB Margulies, ... American Journal of Physiology-Heart and Circulatory Physiology 294 (5 …, 2008 | 42 | 2008 |
Phosphorylation of phospholamban at threonine-17 reduces cardiac adrenergic contractile responsiveness in chronic pressure overload-induced hypertrophy GD Mills, H Kubo, DM Harris, RM Berretta, V Piacentino III, SR Houser American Journal of Physiology-Heart and Circulatory Physiology 291 (1), H61-H70, 2006 | 37 | 2006 |
Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias. CX Zhang X, Ai X, Nakayama H, Chen B, Harris DM, Tang M, Xie Y, Szeto C, Li ... Basic Research in Cardiology 111 (1), 2016 | 34 | 2016 |