Distribution of fixed beneficial mutations and the rate of adaptation in asexual populations BH Good, IM Rouzine, DJ Balick, O Hallatschek, MM Desai Proceedings of the National Academy of Sciences 109 (13), 4950-4955, 2012 | 239 | 2012 |
No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans R Do, D Balick, H Li, I Adzhubei, S Sunyaev, D Reich Nature genetics 47 (2), 126-131, 2015 | 202 | 2015 |
Estimating the selective effects of heterozygous protein-truncating variants from human exome data CA Cassa, D Weghorn, DJ Balick, DM Jordan, D Nusinow, KE Samocha, ... Nature genetics 49 (5), 806-810, 2017 | 156 | 2017 |
Dynamic mutation–selection balance as an evolutionary attractor S Goyal, DJ Balick, ER Jerison, RA Neher, BI Shraiman, MM Desai Genetics 191 (4), 1309-1319, 2012 | 118 | 2012 |
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection AP Schoech, DM Jordan, PR Loh, S Gazal, LJ O’Connor, DJ Balick, ... Nature communications 10 (1), 790, 2019 | 115 | 2019 |
Dominance of deleterious alleles controls the response to a population bottleneck DJ Balick, R Do, CA Cassa, D Reich, SR Sunyaev PLoS genetics 11 (8), e1005436, 2015 | 81 | 2015 |
The landscape of tolerated genetic variation in humans and primates H Gao, T Hamp, J Ede, JG Schraiber, J McRae, M Singer-Berk, Y Yang, ... Science 380 (6648), eabn8153, 2023 | 60 | 2023 |
Applicability of the mutation–selection balance model to population genetics of heterozygous protein-truncating variants in humans D Weghorn, DJ Balick, C Cassa, JA Kosmicki, MJ Daly, DR Beier, ... Molecular Biology and Evolution 36 (8), 1701-1710, 2019 | 29 | 2019 |
Quantification of frequency-dependent genetic architectures and action of negative selection in 25 UK Biobank traits AP Schoech, D Jordan, PR Loh, S Gazal, L O’Connor, DJ Balick, ... BioRxiv, 188086, 2017 | 22 | 2017 |
Overcoming constraints on the detection of recessive selection in human genes from population frequency data DJ Balick, DM Jordan, S Sunyaev, R Do The American Journal of Human Genetics 109 (1), 33-49, 2022 | 11 | 2022 |
The rate of adaptation and the distribution of fixed beneficial mutations in asexual populations BH Good, IM Rouzine, DJ Balick, O Hallatschek, MM Desai Proceedings of the National Academy of Sciences 109, 4950-4955, 2012 | 8 | 2012 |
Response to a population bottleneck can be used to infer recessive selection DJ Balick, R Do, D Reich, SR Sunyaev arXiv preprint arXiv:1312.3028, 2013 | 7 | 2013 |
Quantification of frequency-dependent genetic architectures and action of negative selection in 25 UK Biobank traits. bioRxiv A Schoech, D Jordan, PR Loh, S Gazal, L O’Connor, DJ Balick, ... September, 2017 | 6 | 2017 |
Rare beneficial mutations can halt Muller's ratchet S Goyal, DJ Balick, ER Jerison, RA Neher, BI Shraiman, MM Desai arXiv preprint arXiv:1110.2939, 2011 | 4 | 2011 |
Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy DW Radke, JH Sul, DJ Balick, S Akle, RC Green, SR Sunyaev, ... Genome Research 31 (6), 935-946, 2021 | 3 | 2021 |
Reply to ‘Selective effects of heterozygous protein-truncating variants’ CA Cassa, D Weghorn, DJ Balick, DM Jordan, D Nusinow, KE Samocha, ... Nature genetics 51 (1), 3-4, 2019 | 3 | 2019 |
Rare beneficial mutations can halt Muller's ratchet D Balick, S Goyal, E Jerison, R Neher, B Shraiman, M Desai APS March Meeting Abstracts 2012, B51. 005, 2012 | 2 | 2012 |
Probing the aggregated effects of purifying selection per individual on 1,380 medical phenotypes in the UK biobank HMT Vy, DM Jordan, DJ Balick, R Do PLoS Genetics 17 (1), e1009337, 2021 | 1 | 2021 |
A field theoretic approach to non-equilibrium population genetics in the strong selection regime DJ Balick bioRxiv, 2023 | | 2023 |
Strength of purifying selection on the amino-acid sequence is associated with the amount of non-additive variance in gene expression M Takou, DJ Balick, KA Steige, J Clo, H Dittberner, U Göbel, H Schielzeth, ... bioRxiv, 2022.02. 11.480164, 2022 | | 2022 |