Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G E Papadopoulos, S Jenni, E Kabha, KJ Takrouri, T Yi, N Salvi, RE Luna, ... Proceedings of the National Academy of Sciences 111 (31), E3187-E3195, 2014 | 96 | 2014 |
New reduction pathways for ctc-[PtCl 2 (CH 3 CO 2) 2 (NH 3)(Am)] anticancer prodrugs A Nemirovski, I Vinograd, K Takrouri, A Mijovilovich, A Rompel, D Gibson Chemical Communications 46 (11), 1842-1844, 2010 | 89 | 2010 |
Progress against Escherichia coli with the Oxazolidinone Class of Antibacterials: Test Case for a General Approach To Improving Whole-Cell Gram-Negative Activity K Takrouri, HD Cooper, A Spaulding, P Zucchi, B Koleva, DC Cleary, ... ACS Infectious Diseases 2 (6), 405-426, 2016 | 34 | 2016 |
Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase T Chen, K Takrouri, S Hee-Hwang, S Rana, R Yefidoff-Freedman, ... Journal of medicinal chemistry 56 (23), 9457-9470, 2013 | 31 | 2013 |
Structure–activity relationship study of 4EGI-1, small molecule eIF4E/eIF4G protein–protein interaction inhibitors K Takrouri, T Chen, E Papadopoulos, R Sahoo, E Kabha, H Chen, ... European journal of medicinal chemistry 77, 361-377, 2014 | 30 | 2014 |
Synthesis of rigidified eIF4E/eIF4G inhibitor-1 (4EGI-1) mimetic and their in vitro characterization as inhibitors of protein–protein interaction P Mahalingam, K Takrouri, T Chen, R Sahoo, E Papadopoulos, L Chen, ... Journal of medicinal chemistry 57 (12), 5094-5111, 2014 | 29 | 2014 |
Pharmacologically active boranes A Jabbour, R Smoum, K Takrouri, E Shalom, B Zaks, D Steinberg, ... Pure and applied chemistry 78 (7), 1425-1453, 2006 | 27 | 2006 |
Synthesis and antifungal activity of a novel series of alkyldimethylamine cyanoboranes and their derivatives K Takrouri, G Oren, I Polacheck, E Sionov, E Shalom, J Katzhendler, ... Journal of medicinal chemistry 49 (16), 4879-4885, 2006 | 25 | 2006 |
C-Lithiation/alkylation of trimethylamine cyanoborane K Takrouri, J Katzhendler, M Srebnik Organometallics 23 (11), 2817-2820, 2004 | 23 | 2004 |
Effect of surfactants on the thermodynamic properties of Methyl Orange dye in buffered solutions M Dakiky, M Khamis, A Manasra, K Takrouri Coloration technology 118 (4), 191-197, 2002 | 17 | 2002 |
Compound design guidelines for evading the efflux and permeation barriers of Escherichia coli with the oxazolidinone class of antibacterials: Test case for a general approach … A Spaulding, K Takrouri, P Mahalingam, DC Cleary, HD Cooper, P Zucchi, ... Bioorganic & Medicinal Chemistry Letters 27 (23), 5310-5321, 2017 | 15 | 2017 |
Preparation and Structure Determination of Trimethylamine− Dibromocarboxyborane Esters E Shalom, K Takrouri, I Goldberg, J Katzhendler, M Srebnik Organometallics 23 (19), 4396-4399, 2004 | 15 | 2004 |
Diborane (4) derivatives via coupling of amine monobromocyanoboranes: Study of the bromination of amine cyanoborane and molecular structures of the amine dibromocyanoboranes K Takrouri, E Shalom, I Goldberg, J Katzhendler, M Srebnik Journal of organometallic chemistry 690 (18), 4150-4158, 2005 | 10 | 2005 |
Insight into acid driven formation of spiro-[oxindole] xanthenes from isatin and phenols H Yang, K Takrouri, M Chorev Current Organic Chemistry 16 (13), 1581-1593, 2012 | 9 | 2012 |
Semiautomated synthesis of a novel [18F] amine fluorocyanoborane for PET imaging studies. Radiosynthesis and in vivo characterization in rats E Shalom, K Takrouri, N Metsuyanim, A Grufi, J Katzhendler, M Srebnik Applied radiation and isotopes 65 (2), 204-208, 2007 | 6 | 2007 |
Preparation of novel fluoro derivatives of amine cyanoboranes and amine carboxyborane esters E Shalom, K Takrouri, I Goldberg, J Katzhendler, M Srebnik Organometallics 24 (23), 5776-5779, 2005 | 4 | 2005 |
α-Aminoboronic acids, amine cyanoboranes, amine carboxyboranes and their derivatives K Takrouri, VM Dembistky, M Srebnik Studies in Inorganic Chemistry 22, 495-549, 2005 | 4 | 2005 |
Novel amine-borane compounds and uses thereof M Srebnik, K Takrouri, E Shalom US Patent App. 11/991,850, 2010 | 3 | 2010 |
Crystallographic report: Dimethyl‐2‐phenylethan‐2‐olamine cyanoborane K Takrouri, E Shalom, I Goldberg, J Katzhendler, M Srebnik Applied organometallic chemistry 19 (3), 386-387, 2005 | 3 | 2005 |
Crystallographic report: Trimethylaminedibromopropoxycarbonylborane E Shalom, K Takrouri, I Goldberg, J Katzhendler, M Srebnik Applied organometallic chemistry 19 (3), 391-392, 2005 | 3 | 2005 |