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Structure of the human κ-opioid receptor in complex with JDTic H Wu, D Wacker, M Mileni, V Katritch, GW Han, E Vardy, W Liu, ... Nature 485 (7398), 327-332, 2012 | 1082 | 2012 |
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Automated design of ligands to polypharmacological profiles J Besnard, GF Ruda, V Setola, K Abecassis, RM Rodriguiz, XP Huang, ... Nature 492 (7428), 215-220, 2012 | 853 | 2012 |
Structural features for functional selectivity at serotonin receptors D Wacker, C Wang, V Katritch, GW Han, XP Huang, E Vardy, JD McCorvy, ... Science 340 (6132), 615-619, 2013 | 792 | 2013 |
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome WK Kroeze, MF Sassano, XP Huang, K Lansu, JD McCorvy, PM Giguère, ... Nature structural & molecular biology 22 (5), 362-369, 2015 | 652 | 2015 |
Structural basis for molecular recognition at serotonin receptors C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ... Science 340 (6132), 610-614, 2013 | 600 | 2013 |
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic AA Thompson, W Liu, E Chun, V Katritch, H Wu, E Vardy, XP Huang, ... Nature 485 (7398), 395-399, 2012 | 595 | 2012 |
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells M Vedadi, D Barsyte-Lovejoy, F Liu, S Rival-Gervier, A Allali-Hassani, ... Nature chemical biology 7 (8), 566-574, 2011 | 554 | 2011 |
Molecular control of δ-opioid receptor signalling G Fenalti, PM Giguere, V Katritch, XP Huang, AA Thompson, V Cherezov, ... Nature 506 (7487), 191-196, 2014 | 547 | 2014 |
Structure of the human smoothened receptor bound to an antitumour agent C Wang, H Wu, V Katritch, GW Han, XP Huang, W Liu, FY Siu, BL Roth, ... Nature 497 (7449), 338-343, 2013 | 545 | 2013 |
An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1 KD Konze, A Ma, F Li, D Barsyte-Lovejoy, T Parton, CJ MacNevin, F Liu, ... ACS chemical biology 8 (6), 1324-1334, 2013 | 487 | 2013 |
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Structure of the nanobody-stabilized active state of the kappa opioid receptor T Che, S Majumdar, SA Zaidi, P Ondachi, JD McCorvy, S Wang, ... Cell 172 (1), 55-67. e15, 2018 | 364 | 2018 |
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