Review on epidermal growth factor receptor (EGFR) structure, signaling pathways, interactions, and recent updates of EGFR inhibitors DA Sabbah, R Hajjo, K Sweidan Current topics in medicinal chemistry, 2020 | 335 | 2020 |
Shedding the light on post-vaccine myocarditis and pericarditis in COVID-19 and non-COVID-19 vaccine recipients R Hajjo, DA Sabbah, SK Bardaweel, A Tropsha Vaccines 9 (10), 1186, 2021 | 81 | 2021 |
Docking studies on isoform-specific inhibition of phosphoinositide-3-kinases DA Sabbah, JL Vennerstrom, H Zhong Journal of chemical information and modeling 50 (10), 1887-1898, 2010 | 80 | 2010 |
Dual inhibitors of PI3K/mTOR or mTOR-selective inhibitors: which way shall we go? D a Sabbah, M G Brattain, H Zhong Current medicinal chemistry 18 (36), 5528-5544, 2011 | 65 | 2011 |
Sitagliptin: a potential drug for the treatment of COVID-19? S Bardaweel, R Hajjo, D Sabbah Acta Pharmaceutica, 2020 | 48 | 2020 |
An updated review on SARS-CoV-2 main Proteinase (MPro): protein structure and small-molecule inhibitors DA Sabbah, R Hajjo, SK Bardaweel, HA Zhong Current Topics in Medicinal Chemistry 21 (6), 442-460, 2021 | 42 | 2021 |
N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα) DA Sabbah, NA Simms, W Wang, Y Dong, EL Ezell, MG Brattain, ... Bioorganic & medicinal chemistry 20 (24), 7175-7183, 2012 | 41 | 2012 |
Binding selectivity studies of phosphoinositide 3-kinases using free energy calculations DA Sabbah, JL Vennerstrom, HA Zhong Journal of chemical information and modeling 52 (12), 3213-3224, 2012 | 40 | 2012 |
Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases DA Sabbah, NA Simms, MG Brattain, JL Vennerstrom, H Zhong Bioorganic & medicinal chemistry letters 22 (2), 876-880, 2012 | 39 | 2012 |
Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα) DA Sabbah, M Saada, RA Khalaf, S Bardaweel, K Sweidan, T Al-Qirim, ... Bioorganic & Medicinal Chemistry Letters 25 (16), 3120-3124, 2015 | 38 | 2015 |
Computer-aided design, synthesis, and biological evaluation of new indole-2-carboxamide derivatives as PI3Kα/EGFR inhibitors K Sweidan, DA Sabbah, S Bardaweel, KA Dush, GA Sheikha, ... Bioorganic & medicinal chemistry letters 26 (11), 2685-2690, 2016 | 37 | 2016 |
Advances in the development of class i phosphoinositide 3-kinase (PI3K) inhibitors DA Sabbah, J Hu, HA Zhong Curr. Top. Med. Chem 16 (13), 1413-1426, 2016 | 36 | 2016 |
Monoamine oxidase (MAO) as a potential target for anticancer drug design and development R Aljanabi, L Alsous, DA Sabbah, HI Gul, M Gul, SK Bardaweel Molecules 26 (19), 6019, 2021 | 34 | 2021 |
Phosphatidylinositol 3-kinase (PI3K) inhibitors: a recent update on inhibitor design and clinical trials (2016–2020) DA Sabbah, R Hajjo, SK Bardaweel, HA Zhong Expert Opinion on Therapeutic Patents 31 (10), 877-892, 2021 | 29 | 2021 |
Unlocking the potential of the human microbiome for identifying disease diagnostic biomarkers R Hajjo, DA Sabbah, AQ Al Bawab Diagnostics 12 (7), 1742, 2022 | 28 | 2022 |
Synthesis and preliminary biological evaluation of new heterocyclic carboxamide models K Sweidan, J Engelmann, W Abu Rayyan, D Sabbah, M Abu Zarga, ... Letters in Drug Design & Discovery 12 (5), 417-429, 2015 | 28 | 2015 |
Antilipase and antiproliferative activities of novel fluoroquinolones and triazolofluoroquinolones S Arabiyat, V Kasabri, Y Al‐Hiari, YK Bustanji, R Albashiti, IM Almasri, ... Chemical Biology & Drug Design 90 (6), 1282-1294, 2017 | 26 | 2017 |
Benzoin schiff bases: Design, synthesis, and biological evaluation as potential antitumor agents DA Sabbah, F Al-Tarawneh, WH Talib, K Sweidan, SK Bardaweel, ... Medicinal Chemistry 14 (7), 695-708, 2018 | 24 | 2018 |
Modeling the protonation states of β-secretase binding pocket by molecular dynamics simulations and docking studies DA Sabbah, HA Zhong Journal of Molecular Graphics and Modelling 68, 206-215, 2016 | 22 | 2016 |
Structure-based design: Synthesis, X-ray crystallography, and biological evaluation of N-substituted-4-hydroxy-2-quinolone-3-carboxamides as potential cytotoxic agents DA Sabbah, B Hishmah, K Sweidan, S Bardaweel, M AlDamen, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018 | 21 | 2018 |