Evidence for an alternative glycolytic pathway in rapidly proliferating cells MG Vander Heiden, JW Locasale, KD Swanson, H Sharfi, GJ Heffron, ... Science 329 (5998), 1492-1499, 2010 | 739 | 2010 |
Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine-N-Oxide KA Romano, EI Vivas, D Amador-Noguez, FE Rey MBio 6 (2), 10.1128/mbio. 02481-14, 2015 | 600 | 2015 |
Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer W Lu, MF Clasquin, E Melamud, D Amador-Noguez, AA Caudy, ... Analytical chemistry 82 (8), 3212-3221, 2010 | 593 | 2010 |
Metabolite concentrations, fluxes and free energies imply efficient enzyme usage JO Park, SA Rubin, YF Xu, D Amador-Noguez, J Fan, T Shlomi, ... Nature chemical biology 12 (7), 482-489, 2016 | 402 | 2016 |
Metabolic, epigenetic, and transgenerational effects of gut bacterial choline consumption KA Romano, A Martinez-del Campo, K Kasahara, CL Chittim, EI Vivas, ... Cell host & microbe 22 (3), 279-290. e7, 2017 | 170 | 2017 |
Stoichiometry of Site-specific Lysine Acetylation in an Entire Proteome*♦ J Baeza, JA Dowell, MJ Smallegan, J Fan, D Amador-Noguez, Z Khan, ... Journal of Biological Chemistry 289 (31), 21326-21338, 2014 | 165 | 2014 |
Systems-Level Metabolic Flux Profiling Elucidates a Complete, Bifurcated Tricarboxylic Acid Cycle in Clostridium acetobutylicum D Amador-Noguez, XJ Feng, J Fan, N Roquet, H Rabitz, JD Rabinowitz Journal of bacteriology 192 (17), 4452-4461, 2010 | 158 | 2010 |
Metabolome remodeling during the acidogenic-solventogenic transition in Clostridium acetobutylicum D Amador-Noguez, IA Brasg, XJ Feng, N Roquet, JD Rabinowitz Applied and environmental microbiology 77 (22), 7984-7997, 2011 | 155 | 2011 |
Gene expression profile of long‐lived Ames dwarf mice and Little mice D Amador‐Noguez, K Yagi, S Venable, G Darlington Aging cell 3 (6), 423-441, 2004 | 143 | 2004 |
Alterations in xenobiotic metabolism in the long‐lived Little mice D Amador‐Noguez, A Dean, W Huang, K Setchell, D Moore, G Darlington Aging cell 6 (4), 453-470, 2007 | 141 | 2007 |
The exometabolome of Clostridium thermocellum reveals overflow metabolism at high cellulose loading EK Holwerda, PG Thorne, DG Olson, D Amador-Noguez, NL Engle, ... Biotechnology for biofuels 7, 1-11, 2014 | 128 | 2014 |
Design of synthetic human gut microbiome assembly and butyrate production RL Clark, BM Connors, DM Stevenson, SE Hromada, JJ Hamilton, ... Nature communications 12 (1), 3254, 2021 | 119 | 2021 |
Toward low-cost biological and hybrid biological/catalytic conversion of cellulosic biomass to fuels LR Lynd, GT Beckham, AM Guss, LN Jayakody, EM Karp, C Maranas, ... Energy & Environmental Science 15 (3), 938-990, 2022 | 113 | 2022 |
Metabolic remodeling during biofilm development of Bacillus subtilis T Pisithkul, JW Schroeder, EA Trujillo, P Yeesin, DM Stevenson, ... MBio 10 (3), 10.1128/mbio. 00623-19, 2019 | 106 | 2019 |
Molecular mechanism and evolution of guanylate kinase regulation by (p) ppGpp K Liu, AR Myers, T Pisithkul, KR Claas, KA Satyshur, D Amador-Noguez, ... Molecular cell 57 (4), 735-749, 2015 | 106 | 2015 |
A metabolic pathway for catabolizing levulinic acid in bacteria JM Rand, T Pisithkul, RL Clark, JM Thiede, CR Mehrer, DE Agnew, ... Nature microbiology 2 (12), 1624-1634, 2017 | 99 | 2017 |
Genetic determinants of gut microbiota composition and bile acid profiles in mice JH Kemis, V Linke, KL Barrett, FJ Boehm, LL Traeger, MP Keller, ... PLoS genetics 15 (8), e1008073, 2019 | 98 | 2019 |
Steady-state metabolite concentrations reflect a balance between maximizing enzyme efficiency and minimizing total metabolite load N Tepper, E Noor, D Amador-Noguez, HS Haraldsdóttir, R Milo, ... PloS one 8 (9), e75370, 2013 | 94 | 2013 |
Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase YF Xu, D Amador-Noguez, ML Reaves, XJ Feng, JD Rabinowitz Nature chemical biology 8 (6), 562-568, 2012 | 91 | 2012 |
Autotrophic and mixotrophic metabolism of an anammox bacterium revealed by in vivo 13C and 2H metabolic network mapping CE Lawson, GHL Nuijten, RM de Graaf, TB Jacobson, M Pabst, ... The ISME Journal 15 (3), 673-687, 2021 | 82 | 2021 |