Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase J Elliott, OT Lynch, Y Suessmuth, P Qian, CR Boyd, JF Burrows, R Buick, ... Journal of virology 81 (7), 3428-3436, 2007 | 242 | 2007 |
Advances in anti-viral immune defence: revealing the importance of the IFN JAK/STAT pathway N Raftery, NJ Stevenson Cellular and Molecular Life Sciences 74, 2525-2535, 2017 | 149 | 2017 |
miR-19a: an effective regulator of SOCS3 and enhancer of JAK-STAT signalling AS Collins, CE McCoy, AT Lloyd, C O’Farrelly, NJ Stevenson PloS one 8 (7), e69090, 2013 | 102 | 2013 |
Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I: C C Murray, ÉW Griffin, E O’Loughlin, A Lyons, E Sherwin, S Ahmed, ... Brain, behavior, and immunity 48, 274-286, 2015 | 86 | 2015 |
SOCS3 revisited: a broad regulator of disease, now ready for therapeutic use? R Mahony, S Ahmed, C Diskin, NJ Stevenson Cellular and molecular life sciences 73, 3323-3336, 2016 | 80 | 2016 |
The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility M de La Vega, AA Kelvin, DJ Dunican, C McFarlane, JF Burrows, ... Nature communications 2 (1), 259, 2011 | 75 | 2011 |
Neutrophils: need for standardized nomenclature E McKenna, AU Mhaonaigh, R Wubben, A Dwivedi, T Hurley, LA Kelly, ... Frontiers in immunology 12, 602963, 2021 | 73 | 2021 |
Neutrophils in COVID-19: not innocent bystanders E McKenna, R Wubben, JM Isaza-Correa, AM Melo, AU Mhaonaigh, ... Frontiers in Immunology 13, 864387, 2022 | 68 | 2022 |
The high prevalence of asymptomatic SARS-CoV-2 infection reveals the silent spread of COVID-19 MA Almadhi, A Abdulrahman, SA Sharaf, D AlSaad, NJ Stevenson, ... International journal of infectious diseases 105, 656-661, 2021 | 65 | 2021 |
Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes NJ Stevenson, NM Bourke, EJ Ryan, M Binder, L Fanning, JA Johnston, ... FEBS letters 587 (10), 1571-1578, 2013 | 63 | 2013 |
Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation: contributions of Src-and receptor-tyrosine kinases U Sommer, C Schmid, RM Sobota, U Lehmann, NJ Stevenson, ... Journal of Biological Chemistry 280 (36), 31478-31488, 2005 | 63 | 2005 |
Ribavirin enhances IFN-α signalling and MxA expression: a novel immune modulation mechanism during treatment of HCV NJ Stevenson, AG Murphy, NM Bourke, CA Keogh, JE Hegarty, ... PloS one 6 (11), e27866, 2011 | 61 | 2011 |
MicroRNA: master controllers of intracellular signaling pathways PY Lui, DY Jin, NJ Stevenson Cellular and molecular life sciences 72, 3531-3542, 2015 | 57 | 2015 |
Hepatitis C virus (HCV)-induced suppressor of cytokine signaling (SOCS) 3 regulates proinflammatory TNF-α responses AS Collins, S Ahmed, S Napoletano, M Schroeder, JA Johnston, ... Journal of leukocyte biology 96 (2), 255-263, 2014 | 50 | 2014 |
A novel anti-viral role for STAT3 in IFN-α signalling responses R Mahony, S Gargan, KL Roberts, N Bourke, SE Keating, AG Bowie, ... Cellular and Molecular Life Sciences 74, 1755-1764, 2017 | 49 | 2017 |
The chemoattractants, IL-8 and formyl-methionyl-leucyl-phenylalanine, regulate granulocyte colony-stimulating factor signaling by inducing suppressor of cytokine signaling-1 … NJ Stevenson, S Haan, AE McClurg, MJ McGrattan, MA Armstrong, ... The Journal of Immunology 173 (5), 3243-3249, 2004 | 49 | 2004 |
HIV-1 promotes the degradation of components of the type 1 IFN JAK/STAT pathway and blocks anti-viral ISG induction S Gargan, S Ahmed, R Mahony, C Bannan, S Napoletano, C O'farrelly, ... EBioMedicine 30, 203-216, 2018 | 47 | 2018 |
Revisiting respiratory syncytial virus’s interaction with host immunity, towards novel therapeutics C Efstathiou, SH Abidi, J Harker, NJ Stevenson Cellular and Molecular Life Sciences 77, 5045-5058, 2020 | 46 | 2020 |
CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression NJ Stevenson, MR Addley, EJ Ryan, CR Boyd, HP Carroll, V Paunovic, ... Journal of Leucocyte Biology 85 (2), 289-297, 2009 | 42 | 2009 |
Potential role of flavivirus NS2B-NS3 proteases in viral pathogenesis and anti-flavivirus drug discovery employing animal cells and models: a review A Wahaab, BE Mustafa, M Hameed, NJ Stevenson, MN Anwar, K Liu, ... Viruses 14 (1), 44, 2021 | 39 | 2021 |