Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features AK Azab, J Hu, P Quang, F Azab, C Pitsillides, R Awwad, B Thompson, ... Blood, The Journal of the American Society of Hematology 119 (24), 5782-5794, 2012 | 368 | 2012 |
COVID-19 infection induces readily detectable morphological and inflammation-related phenotypic changes in peripheral blood monocytes, the severity of which correlate with … D Zhang, R Guo, L Lei, H Liu, Y Wang, Y Wang, H Qian, T Dai, T Zhang, ... MedRxiv, 2020.03. 24.20042655, 2020 | 245 | 2020 |
Frontline Science: COVID-19 infection induces readily detectable morphologic and inflammation-related phenotypic changes in peripheral blood monocytes D Zhang, R Guo, L Lei, H Liu, Y Wang, Y Wang, H Qian, T Dai, T Zhang, ... Journal of Leucocyte Biology 109 (1), 13-22, 2021 | 189 | 2021 |
Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug J Hu, DR Handisides, E Van Valckenborgh, H De Raeve, E Menu, ... Blood, The Journal of the American Society of Hematology 116 (9), 1524-1527, 2010 | 170 | 2010 |
Activation of ATF4 mediates unwanted Mcl-1 accumulation by proteasome inhibition J Hu, N Dang, E Menu, E De Bryune, D Xu, B Van Camp, ... Blood, The Journal of the American Society of Hematology 119 (3), 826-837, 2012 | 100 | 2012 |
Leptin correlates with monocytes activation and severe condition in COVID-19 patients J Wang, Y Xu, X Zhang, S Wang, Z Peng, J Guo, H Jiang, J Liu, Y Xie, ... Journal of leukocyte biology 110 (1), 9-20, 2021 | 89 | 2021 |
The phenotypic changes of γδ T cells in COVID‐19 patients L Lei, H Qian, X Yang, X Zhang, D Zhang, T Dai, R Guo, L Shi, Y Cheng, ... Journal of Cellular and Molecular Medicine 24 (19), 11603-11606, 2020 | 75 | 2020 |
Understanding the hypoxic niche of multiple myeloma: therapeutic implications and contributions of mouse models J Hu, E Van Valckenborgh, E Menu, E De Bruyne, K Vanderkerken Disease models & mechanisms 5 (6), 763-771, 2012 | 73 | 2012 |
Dll1/Notch activation contributes to bortezomib resistance by upregulating CYP1A1 in multiple myeloma D Xu, J Hu, E De Bruyne, E Menu, R Schots, K Vanderkerken, ... Biochemical and biophysical research communications 428 (4), 518-524, 2012 | 65 | 2012 |
Synergistic Induction of Apoptosis in Multiple Myeloma Cells by Bortezomib and Hypoxia-Activated Prodrug TH-302, In Vivo and In Vitro J Hu, E Van Valckenborgh, D Xu, E Menu, H De Raeve, E De Bryune, ... Molecular cancer therapeutics 12 (9), 1763-1773, 2013 | 64 | 2013 |
Dll1/Notch activation accelerates multiple myeloma disease development by promoting CD138+ MM-cell proliferation D Xu, J Hu, S Xu, E De Bruyne, E Menu, B Van Camp, K Vanderkerken, ... Leukemia 26 (6), 1402-1405, 2012 | 60 | 2012 |
Impaired osteogenic differentiation of mesenchymal stem cells derived from multiple myeloma patients is associated with a blockade in the deactivation of the Notch signaling … S Xu, H Evans, C Buckle, K De Veirman, J Hu, D Xu, E Menu, ... Leukemia 26 (12), 2546-2549, 2012 | 59 | 2012 |
Hypoxia Impairs NK Cell Cytotoxicity through SHP‐1‐Mediated Attenuation of STAT3 and ERK Signaling Pathways R Teng, Y Wang, N Lv, D Zhang, RA Williamson, L Lei, P Chen, L Lei, ... Journal of Immunology Research 2020 (1), 4598476, 2020 | 46 | 2020 |
Hypoxia promotes osteosarcoma cell proliferation and migration through enhancing platelet-derived growth factor-BB/platelet-derived growth factor receptor-β axis D Zhang, G Cui, C Sun, L Lei, L Lei, RA Williamson, Y Wang, J Zhang, ... Biochemical and biophysical research communications 512 (2), 360-366, 2019 | 38 | 2019 |
Involvement of HAb18G/CD147 in T cell activation and immunological synapse formation J Hu, N Dang, H Yao, Y Li, H Zhang, X Yang, J Xu, H Bian, J Xing, P Zhu, ... Journal of Cellular and Molecular Medicine 14 (8), 2132-2143, 2010 | 38 | 2010 |
Analysis of adaptive immune cell populations and phenotypes in the patients infected by SARS-CoV-2 X Yang, T Dai, X Zhou, H Qian, R Guo, L Lei, X Zhang, D Zhang, L Shi, ... MedRxiv, 2020.03. 23.20040675, 2020 | 37 | 2020 |
ER stress arm XBP1s plays a pivotal role in proteasome inhibition-induced bone formation D Zhang, K De Veirman, R Fan, Q Jian, Y Zhang, L Lei, H Evans, Y Wang, ... Stem cell research & therapy 11, 1-13, 2020 | 35 | 2020 |
IGF-1 promotes multiple myeloma progression through PI3K/Akt-mediated epithelial-mesenchymal transition Y Peng, F Li, P Zhang, X Wang, Y Shen, Y Feng, Y Jia, R Zhang, J Hu, ... Life sciences 249, 117503, 2020 | 33 | 2020 |
Naturally activated adaptive immunity in COVID‐19 patients X Yang, T Dai, X Zhou, H Qian, R Guo, L Lei, X Zhang, D Zhang, L Shi, ... Journal of cellular and molecular medicine 24 (21), 12457-12463, 2020 | 30 | 2020 |
Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma L Huang, Y Wang, J Bai, Y Yang, F Wang, Y Feng, R Zhang, F Li, P Zhang, ... Cell Stress and Chaperones 25 (2), 357-367, 2020 | 24 | 2020 |