High throughput thermostability screening of monoclonal antibody formulations F He, S Hogan, RF Latypov, LO Narhi, VI Razinkov Journal of pharmaceutical sciences 99 (4), 1707-1720, 2010 | 213 | 2010 |
Effective charge measurements reveal selective and preferential accumulation of anions, but not cations, at the protein surface in dilute salt solutions YR Gokarn, RM Fesinmeyer, A Saluja, V Razinkov, SF Chase, TM Laue, ... Protein Science 20 (3), 580-587, 2011 | 154 | 2011 |
Acid-induced aggregation of human monoclonal IgG1 and IgG2: molecular mechanism and the effect of solution composition SB Hari, H Lau, VI Razinkov, S Chen, RF Latypov Biochemistry 49 (43), 9328-9338, 2010 | 147 | 2010 |
High-throughput dynamic light scattering method for measuring viscosity of concentrated protein solutions F He, GW Becker, JR Litowski, LO Narhi, DN Brems, VI Razinkov Analytical biochemistry 399 (1), 141-143, 2010 | 143 | 2010 |
Biophysical characterization of influenza virus subpopulations using field flow fractionation and multiangle light scattering: correlation of particle counts, size distribution … Z Wei, M Mcevoy, V Razinkov, A Polozova, E Li, J Casas-Finet, GI Tous, ... Journal of virological methods 144 (1-2), 122-132, 2007 | 115 | 2007 |
High‐throughput assessment of thermal and colloidal stability parameters for monoclonal antibody formulations F He, CE Woods, GW Becker, LO Narhi, VI Razinkov Journal of pharmaceutical sciences 100 (12), 5126-5141, 2011 | 111 | 2011 |
Effect of sugar molecules on the viscosity of high concentration monoclonal antibody solutions F He, CE Woods, JR Litowski, LA Roschen, HS Gadgil, VI Razinkov, ... Pharmaceutical research 28, 1552-1560, 2011 | 107 | 2011 |
Native-state solubility and transfer free energy as predictive tools for selecting excipients to include in protein formulation development studies DD Banks, RF Latypov, RR Ketchem, J Woodard, JL Scavezze, CC Siska, ... Journal of pharmaceutical sciences 101 (8), 2720-2732, 2012 | 106 | 2012 |
RFI-641 inhibits entry of respiratory syncytial virus via interactions with fusion protein V Razinkov, A Gazumyan, A Nikitenko, G Ellestad, G Krishnamurthy Chemistry & biology 8 (7), 645-659, 2001 | 100 | 2001 |
A novel antibody engineering strategy for making monovalent bispecific heterodimeric IgG antibodies by electrostatic steering mechanism Z Liu, EC Leng, K Gunasekaran, M Pentony, M Shen, M Howard, J Stoops, ... Journal of Biological Chemistry 290 (12), 7535-7562, 2015 | 94 | 2015 |
Aggregation of anti-streptavidin immunoglobulin gamma‐1 involves Fab unfolding and competing growth pathways mediated by pH and salt concentration N Kim, RL Remmele Jr, D Liu, VI Razinkov, EJ Fernandez, CJ Roberts Biophysical chemistry 172, 26-36, 2013 | 93 | 2013 |
Screening of monoclonal antibody formulations based on high-throughput thermostability and viscosity measurements: design of experiment and statistical analysis F He, CE Woods, E Trilisky, KM Bower, JR Litowski, BA Kerwin, ... Journal of pharmaceutical sciences 100 (4), 1330-1340, 2011 | 89 | 2011 |
Accelerated formulation development of monoclonal antibodies (mAbs) and mAb-based modalities: review of methods and tools VI Razinkov, MJ Treuheit, GW Becker Journal of biomolecular screening 20 (4), 468-483, 2015 | 80 | 2015 |
Specific-ion effects on the aggregation mechanisms and protein–protein interactions for anti-streptavidin immunoglobulin gamma-1 GV Barnett, VI Razinkov, BA Kerwin, TM Laue, AH Woodka, PD Butler, ... The Journal of Physical Chemistry B 119 (18), 5793-5804, 2015 | 79 | 2015 |
Effects of Spontaneous Bilayer Curvature on Influenza Virus–mediated Fusion Pores VI Razinkov, GB Melikyan, RM Epand, RF Epand, FS Cohen The Journal of general physiology 112 (4), 409-422, 1998 | 74 | 1998 |
How Well Do Low-and High-Concentration Protein Interactions Predict Solution Viscosities of Monoclonal Antibodies? MA Woldeyes, W Qi, VI Razinkov, EM Furst, CJ Roberts Journal of pharmaceutical sciences, 2018 | 71 | 2018 |
Detection of IgG aggregation by a high throughput method based on extrinsic fluorescence F He, DH Phan, S Hogan, R Bailey, GW Becker, LO Narhi, VI Razinkov Journal of pharmaceutical sciences 99 (6), 2598-2608, 2010 | 70 | 2010 |
Asymmetrical Fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies Z Liu, K Gunasekaran, W Wang, V Razinkov, L Sekirov, E Leng, H Sweet, ... Journal of Biological Chemistry 289 (6), 3571-3590, 2014 | 65 | 2014 |
Sterols and sphingolipids strongly affect the growth of fusion pores induced by the hemagglutinin of influenza virus VI Razinkov, FS Cohen Biochemistry 39 (44), 13462-13468, 2000 | 53 | 2000 |
Precision of protein aggregation measurements by sedimentation velocity analytical ultracentrifugation in biopharmaceutical applications JP Gabrielson, KK Arthur, MR Stoner, BC Winn, BS Kendrick, V Razinkov, ... Analytical biochemistry 396 (2), 231-241, 2010 | 52 | 2010 |