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Brian J. Cafferty
Brian J. Cafferty
Director, Beam Therapeutics
在 beamtx.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
The origin of RNA and “my grandfather’s axe”
NV Hud, BJ Cafferty, R Krishnamurthy, LD Williams
Chemistry & biology 20 (4), 466-474, 2013
2482013
The synthesis of cyclic poly (ethylene imine) and exact linear analogues: an evaluation of gene delivery comparing polymer architectures
MA Cortez, WT Godbey, Y Fang, ME Payne, BJ Cafferty, KA Kosakowska, ...
Journal of the american chemical society 137 (20), 6541-6549, 2015
2122015
Efficient self-assembly in water of long noncovalent polymers by nucleobase analogues
BJ Cafferty, I Gállego, MC Chen, KI Farley, R Eritja, NV Hud
Journal of the American Chemical Society 135 (7), 2447-2450, 2013
1872013
Darwin's warm little pond: a one‐pot reaction for prebiotic phosphorylation and the mobilization of phosphate from minerals in a urea‐based solvent
B Burcar, M Pasek, M Gull, BJ Cafferty, F Velasco, NV Hud, ...
Angewandte Chemie International Edition 55 (42), 13249-13253, 2016
1462016
Spontaneous formation and base pairing of plausible prebiotic nucleotides in water
BJ Cafferty, DM Fialho, J Khanam, R Krishnamurthy, NV Hud
Nature communications 7 (1), 11328, 2016
1362016
Spontaneous Prebiotic Formation of a β-Ribofuranoside That Self-Assembles with a Complementary Heterocycle
MC Chen, BJ Cafferty, I Mamajanov, I Gállego, J Khanam, ...
Journal of the American Chemical Society 136 (15), 5640–5646, 2014
992014
Abiotic synthesis of RNA in water: a common goal of prebiotic chemistry and bottom-up synthetic biology
BJ Cafferty, NV Hud
Current opinion in chemical biology 22, 146-157, 2014
962014
Storage of information using small organic molecules
BJ Cafferty, AS Ten, MJ Fink, S Morey, DJ Preston, M Mrksich, ...
ACS central science 5 (5), 911-916, 2019
912019
Spontaneous symmetry breaking in the formation of supramolecular polymers: implications for the origin of biological homochirality
SC Karunakaran, BJ Cafferty, A Weigert‐Muñoz, GB Schuster, NV Hud
Angewandte Chemie 131 (5), 1467-1471, 2019
732019
Was a Pyrimidine‐Pyrimidine Base Pair the Ancestor of Watson‐Crick Base Pairs? Insights from a Systematic Approach to the Origin of RNA
BJ Cafferty, NV Hud
Israel Journal of Chemistry 55 (8), 891-905, 2015
652015
Autocatalytic Cycles in a Copper-Catalyzed Azide–Alkyne Cycloaddition Reaction
SN Semenov, L Belding, BJ Cafferty, MPS Mousavi, AM Finogenova, ...
Journal of the American Chemical Society 140 (32), 10221-10232, 2018
642018
Robustness, entrainment, and hybridization in dissipative molecular networks, and the origin of life
BJ Cafferty, ASY Wong, SN Semenov, L Belding, S Gmur, WTS Huck, ...
Journal of the American Chemical Society 141 (20), 8289-8295, 2019
532019
Ultra-sensitive pH control of supramolecular polymers and hydrogels: p K a matching of biomimetic monomers
BJ Cafferty, RR Avirah, GB Schuster, NV Hud
Chemical Science 5 (12), 4681-4686, 2014
452014
Fabricating 3D structures by combining 2D printing and relaxation of strain
BJ Cafferty, VE Campbell, P Rothemund, DJ Preston, A Ainla, ...
Advanced Materials Technologies 4 (1), 1800299, 2019
442019
Improved CRISPR genome editing using small highly active and specific engineered RNA-guided nucleases
MJ Schmidt, A Gupta, C Bednarski, S Gehrig-Giannini, F Richter, C Pitzler, ...
Nature communications 12 (1), 4219, 2021
422021
Formation of supramolecular assemblies and liquid crystals by purine nucleobases and cyanuric acid in water: Implications for the possible origins of RNA
C Li, BJ Cafferty, SC Karunakaran, GB Schuster, NV Hud
Physical Chemistry Chemical Physics 18 (30), 20091-20096, 2016
392016
Storing and reading information in mixtures of fluorescent molecules
AA Nagarkar, SE Root, MJ Fink, AS Ten, BJ Cafferty, DS Richardson, ...
ACS Central Science 7 (10), 1728-1735, 2021
372021
Silicate-promoted phosphorylation of glycerol in non-aqueous solvents: a prebiotically plausible route to organophosphates
M Gull, BJ Cafferty, NV Hud, MA Pasek
Life 7 (3), 29, 2017
302017
Water-soluble supramolecular polymers of paired and stacked heterocycles: Assembly, structure, properties, and a possible path to pre-RNA
GB Schuster, BJ Cafferty, SC Karunakaran, NV Hud
Journal of the American Chemical Society 143 (25), 9279-9296, 2021
282021
Evaluation of cytosine base editing and adenine base editing as a potential treatment for alpha-1 antitrypsin deficiency
MS Packer, V Chowdhary, G Lung, LI Cheng, Y Aratyn-Schaus, ...
Molecular Therapy 30 (4), 1396-1406, 2022
212022
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