CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism J Camacho-Pereira, MG Tarragó, CCS Chini, V Nin, C Escande, ... Cell metabolism 23 (6), 1127-1139, 2016 | 768 | 2016 |
Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome C Escande, V Nin, NL Price, V Capellini, AP Gomes, MT Barbosa, ... Diabetes 62 (4), 1084-1093, 2013 | 363 | 2013 |
Deleted in breast cancer–1 regulates SIRT1 activity and contributes to high-fat diet–induced liver steatosis in mice C Escande, CCS Chini, V Nin, KM Dykhouse, CM Novak, J Levine, ... The Journal of clinical investigation 120 (2), 545-558, 2010 | 217 | 2010 |
Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38 P Aksoy, C Escande, TA White, M Thompson, S Soares, JC Benech, ... Biochemical and biophysical research communications 349 (1), 353-359, 2006 | 207 | 2006 |
Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors CCS Chini, AMG Guerrico, V Nin, J Camacho-Pereira, C Escande, ... Clinical cancer research 20 (1), 120-130, 2014 | 148 | 2014 |
Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase V Nin, C Escande, CC Chini, S Giri, J Camacho-Pereira, J Matalonga, ... Journal of Biological Chemistry 287 (28), 23489-23501, 2012 | 132 | 2012 |
Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice MB Stout, T Tchkonia, T Pirtskhalava, AK Palmer, EO List, DE Berryman, ... Aging (Albany NY) 6 (7), 575, 2014 | 122 | 2014 |
Potential modulation of sirtuins by oxidative stress L Santos, C Escande, A Denicola Oxidative medicine and cellular longevity 2016 (1), 9831825, 2016 | 121 | 2016 |
Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity CM Novak, C Escande, PR Burghardt, M Zhang, MT Barbosa, EN Chini, ... Hormones and behavior 58 (3), 355-367, 2010 | 112 | 2010 |
The nuclear receptor LXR limits bacterial infection of host macrophages through a mechanism that impacts cellular NAD metabolism J Matalonga, E Glaria, M Bresque, C Escande, JM Carbó, K Kiefer, ... Cell reports 18 (5), 1241-1255, 2017 | 108 | 2017 |
HDAC3 is negatively regulated by the nuclear protein DBC1 CCS Chini, C Escande, V Nin, EN Chini Journal of Biological Chemistry 285 (52), 40830-40837, 2010 | 103 | 2010 |
Endurance capacity, not body size, determines physical activity levels: role of skeletal muscle PEPCK CM Novak, C Escande, SM Gerber, EN Chini, M Zhang, SL Britton, ... PloS one 4 (6), e5869, 2009 | 69 | 2009 |
Early and late calcium waves during wound healing in corneal endothelial cells S Chifflet, C Justet, JA Hernández, V Nin, C Escande, JC Benech Wound Repair and Regeneration 20 (1), 28-37, 2012 | 51 | 2012 |
Deleted in breast cancer-1 (DBC-1) in the interface between metabolism, aging and cancer EN Chini, CCS Chini, V Nin, C Escande Bioscience reports 33 (4), e00058, 2013 | 48 | 2013 |
Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes … G Lomberk, A Grzenda, A Mathison, C Escande, JS Zhang, E Calvo, ... Journal of Biological Chemistry 288 (24), 17745-17758, 2013 | 48 | 2013 |
DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbα CCS Chini, C Escande, V Nin, EN Chini Biochemical Journal 451 (3), 453-461, 2013 | 48 | 2013 |
CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system WR Hartman, LL Pelleymounter, I Moon, K Kalari, M Liu, TY Wu, ... Leukemia & lymphoma 51 (7), 1315-1325, 2010 | 43 | 2010 |
SIRT1-activating compounds (STAC) negatively regulate pancreatic cancer cell growth and viability through a SIRT1 lysosomal-dependent pathway CCS Chini, JM Espindola-Netto, G Mondal, AMG Guerrico, V Nin, ... Clinical Cancer Research 22 (10), 2496-2507, 2016 | 38 | 2016 |
Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells J Martínez, D Tarallo, L Martínez-Palma, S Victoria, M Bresque, ... Biochemical Journal 476 (17), 2463-2486, 2019 | 33 | 2019 |
Deleted in breast cancer 1 limits adipose tissue fat accumulation and plays a key role in the development of metabolic syndrome phenotype C Escande, V Nin, T Pirtskhalava, CCS Chini, T Tchkonia, JL Kirkland, ... Diabetes 64 (1), 12-22, 2015 | 33 | 2015 |