Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus RK Perez, MG Gordon, M Subramaniam, MC Kim, GC Hartoularos, S Targ, ... Science 376 (6589), eabf1970, 2022 | 211 | 2022 |
Ultra-rare variants drive substantial cis-heritability of human gene expression RD Hernandez, LH Uricchio, K Hartman, C Ye, A Dahl, N Zaitlen Nature genetics 51, 1349–1355, 2019 | 140* | 2019 |
A multiple-phenotype imputation method for genetic studies A Dahl, V Iotchkova, A Baud, Å Johansson, U Gyllensten, N Soranzo, ... Nature genetics 48 (4), 466-472, 2016 | 107 | 2016 |
Cross-trait assortative mating is widespread and inflates genetic correlation estimates R Border, G Athanasiadis, A Buil, AJ Schork, N Cai, AI Young, T Werge, ... Science 378 (6621), 754-761, 2022 | 93 | 2022 |
Molecular genetic analysis subdivided by adversity exposure suggests etiologic heterogeneity in major depression RE Peterson, N Cai, AW Dahl, TB Bigdeli, AC Edwards, BT Webb, ... American Journal of Psychiatry 175 (6), 545-554, 2018 | 80 | 2018 |
A robust method uncovers significant context-specific heritability in diverse complex traits A Dahl, K Nguyen, N Cai, MJ Gandal, J Flint, N Zaitlen The American Journal of Human Genetics 106 (1), 71-91, 2020 | 63 | 2020 |
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes JK Goodrich, M Singer-Berk, R Son, A Sveden, J Wood, E England, ... Nature communications 12 (1), 3505, 2021 | 60 | 2021 |
On the cross-population generalizability of gene expression prediction models KL Keys, ACY Mak, MJ White, WL Eckalbar, AW Dahl, J Mefford, ... PLoS genetics 16 (8), e1008927, 2020 | 53* | 2020 |
Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE C Caggiano, B Celona, F Garton, J Mefford, BL Black, R Henderson, ... Nature communications 12 (1), 2717, 2021 | 47* | 2021 |
Reverse GWAS: Using genetics to identify and model phenotypic subtypes A Dahl, N Cai, A Ko, M Laakso, P Pajukanta, J Flint, N Zaitlen PLoS genetics 15 (4), e1008009, 2019 | 46 | 2019 |
Genomic response to vitamin D supplementation in the setting of a randomized, placebo-controlled trial AJ Berlanga-Taylor, K Plant, A Dahl, E Lau, M Hill, D Sims, A Heger, ... EBioMedicine 31, 133-142, 2018 | 37 | 2018 |
On negative heritability and negative estimates of heritability D Steinsaltz, A Dahl, KW Wachter Genetics 215 (2), 343-357, 2020 | 35 | 2020 |
Detecting clusters in atom probe data with Gaussian mixture models J Zelenty, A Dahl, J Hyde, GDW Smith, MP Moody Microscopy and Microanalysis 23 (2), 269-278, 2017 | 33 | 2017 |
Genetic influences on disease subtypes A Dahl, N Zaitlen Annual review of genomics and human genetics 21 (1), 413-435, 2020 | 28 | 2020 |
Adjusting for principal components of molecular phenotypes induces replicating false positives A Dahl, V Guillemot, J Mefford, H Aschard, N Zaitlen Genetics 211 (4), 1179-1189, 2019 | 27 | 2019 |
GBAT: a gene-based association test for robust detection of trans-gene regulation X Liu, JA Mefford, A Dahl, Y He, M Subramaniam, A Battle, AL Price, ... Genome biology 21, 1-14, 2020 | 22* | 2020 |
A model and test for coordinated polygenic epistasis in complex traits B Sheppard, N Rappoport, PR Loh, SJ Sanders, N Zaitlen, A Dahl Proceedings of the National Academy of Sciences 118 (15), e1922305118, 2021 | 18* | 2021 |
Deep learning-based phenotype imputation on population-scale biobank data increases genetic discoveries U An, A Pazokitoroudi, M Alvarez, L Huang, S Bacanu, AJ Schork, ... Nature Genetics, 1-8, 2023 | 16 | 2023 |
Statistical properties of simple random-effects models for genetic heritability D Steinsaltz, A Dahl, KW Wachter Electronic journal of statistics 12 (1), 321, 2018 | 15 | 2018 |
Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder A Dahl, M Thompson, U An, M Krebs, V Appadurai, R Border, SA Bacanu, ... Nature Genetics 55 (12), 2082-2093, 2023 | 13* | 2023 |