Single-particle cryo-EM at atomic resolution T Nakane, A Kotecha, A Sente, G McMullan, S Masiulis, PMGE Brown, ... Nature 587 (7832), 152-156, 2020 | 779 | 2020 |
Nanostructured films from hierarchical self-assembly of amyloidogenic proteins TPJ Knowles, TW Oppenheim, AK Buell, DY Chirgadze, ME Welland Nature nanotechnology 5 (3), 204-207, 2010 | 411 | 2010 |
Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats BL Sibanda, DY Chirgadze, TL Blundell Nature 463 (7277), 118-121, 2010 | 260 | 2010 |
Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody J Sanders, DY Chirgadze, P Sanders, S Baker, A Sullivan, A Bhardwaja, ... Thyroid 17 (5), 395-410, 2007 | 245 | 2007 |
DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair BL Sibanda, DY Chirgadze, DB Ascher, TL Blundell Science 355 (6324), 520-524, 2017 | 182 | 2017 |
5-Formylcytosine alters the structure of the DNA double helix EA Raiber, P Murat, DY Chirgadze, D Beraldi, BF Luisi, ... Nature structural & molecular biology 22 (1), 44-49, 2015 | 181 | 2015 |
The Crystal Structure of Fibroblast Growth Factor (FGF) 19 Reveals Novel Features of the FGF Family and Offers a Structural Basis for Its Unusual Receptor Affinity, NJ Harmer, L Pellegrini, D Chirgadze, J Fernandez-Recio, TL Blundell Biochemistry 43 (3), 629-640, 2004 | 178 | 2004 |
Expanding the solvent chemical space for self-assembly of dipeptide nanostructures TO Mason, DY Chirgadze, A Levin, L Adler-Abramovich, E Gazit, ... ACS nano 8 (2), 1243-1253, 2014 | 177 | 2014 |
Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding DY Chirgadze, JP Hepple, H Zhou, RA Byrd, TL Blundell, E Gherardi Nature structural biology 6 (1), 72-79, 1999 | 157 | 1999 |
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ Y Li, DY Chirgadze, VM Bolanos‐Garcia, BL Sibanda, OR Davies, ... The EMBO journal 27 (1), 290-300, 2008 | 143 | 2008 |
Crystal structures of NK1–heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor D Lietha, DY Chirgadze, B Mulloy, TL Blundell, E Gherardi The EMBO Journal 20 (20), 5543-5555, 2001 | 138 | 2001 |
A new look at sodium channel β subunits S Namadurai, NR Yereddi, FS Cusdin, CLH Huang, DY Chirgadze, ... Open biology 5 (1), 140192, 2015 | 133 | 2015 |
Characteristics of a human monoclonal autoantibody to the thyrotropin receptor: sequence structure and function J Sanders, J Jeffreys, H Depraetere, M Evans, T Richards, A Kiddie, ... Thyroid 14 (8), 560-570, 2004 | 118 | 2004 |
Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer RK Nookala, L Langemeyer, A Pacitto, B Ochoa-Montano, JC Donaldson, ... Open biology 2 (8), 120071, 2012 | 108 | 2012 |
Non-homologous end-joining partners in a helical dance: structural studies of XLF–XRCC4 interactions Q Wu, T Ochi, D Matak-Vinkovic, CV Robinson, DY Chirgadze, ... Biochemical Society Transactions 39 (5), 1387-1392, 2011 | 92 | 2011 |
Structure of an Xrcc4–DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode AS Doré, N Furnham, OR Davies, BL Sibanda, DY Chirgadze, ... DNA repair 5 (3), 362-368, 2006 | 88 | 2006 |
Dimers of DNA-PK create a stage for DNA double-strand break repair AK Chaplin, SW Hardwick, S Liang, A Kefala Stavridi, A Hnizda, ... Nature structural & molecular biology 28 (1), 13-19, 2021 | 87 | 2021 |
Crystal structure and molecular imaging of the Nav channel β3 subunit indicates a trimeric assembly S Namadurai, D Balasuriya, R Rajappa, M Wiemhöfer, K Stott, J Klingauf, ... Journal of Biological Chemistry 289 (15), 10797-10811, 2014 | 85 | 2014 |
Structural constraints on protein self‐processing in l‐aspartate‐α‐decarboxylase F Schmitzberger, ML Kilkenny, CMC Lobley, ME Webb, M Vinkovic, ... The EMBO journal, 2003 | 83 | 2003 |
Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site VM Bolanos-Garcia, T Lischetti, D Matak-Vinković, E Cota, PJ Simpson, ... Structure 19 (11), 1691-1700, 2011 | 82 | 2011 |