Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung AA Pezzulo, XX Tang, MJ Hoegger, MH Abou Alaiwa, S Ramachandran, ... Nature 487 (7405), 109-113, 2012 | 963 | 2012 |
Airway acidification initiates host defense abnormalities in cystic fibrosis mice VS Shah, DK Meyerholz, XX Tang, L Reznikov, M Abou Alaiwa, SE Ernst, ... Science 351 (6272), 503-507, 2016 | 330 | 2016 |
pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37 MH Abou Alaiwa, LR Reznikov, ND Gansemer, KA Sheets, AR Horswill, ... Proceedings of the National Academy of Sciences 111 (52), 18703-18708, 2014 | 230 | 2014 |
Gel-forming mucins form distinct morphologic structures in airways LS Ostedgaard, TO Moninger, JD McMenimen, NM Sawin, CP Parker, ... Proceedings of the National Academy of Sciences 114 (26), 6842-6847, 2017 | 160 | 2017 |
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs DA Stoltz, T Rokhlina, SE Ernst, AA Pezzulo, LS Ostedgaard, PH Karp, ... The Journal of clinical investigation 123 (6), 2685-2693, 2013 | 144 | 2013 |
CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes B Steines, DD Dickey, J Bergen, KJDA Excoffon, JR Weinstein, X Li, ... JCI insight 1 (14), 2016 | 117 | 2016 |
Lentiviral-mediated phenotypic correction of cystic fibrosis pigs AL Cooney, MH Abou Alaiwa, VS Shah, DC Bouzek, MR Stroik, ... JCI insight 1 (14), 2016 | 105 | 2016 |
Antibacterial properties of the CFTR potentiator ivacaftor LR Reznikov, MH Abou Alaiwa, CL Dohrn, ND Gansemer, DJ Diekema, ... Journal of Cystic Fibrosis 13 (5), 515-519, 2014 | 103 | 2014 |
Neonates with cystic fibrosis have a reduced nasal liquid pH; a small pilot study MH Abou Alaiwa, AM Beer, AA Pezzulo, JL Launspach, RA Horan, ... Journal of cystic fibrosis 13 (4), 373-377, 2014 | 95 | 2014 |
Air trapping and airflow obstruction in newborn cystic fibrosis piglets RJ Adam, AS Michalski, C Bauer, MH Abou Alaiwa, TJ Gross, ... American journal of respiratory and critical care medicine 188 (12), 1434-1441, 2013 | 76 | 2013 |
Cystic fibrosis transmembrane conductance regulator in sarcoplasmic reticulum of airway smooth muscle. Implications for airway contractility DP Cook, MV Rector, DC Bouzek, AS Michalski, ND Gansemer, ... American journal of respiratory and critical care medicine 193 (4), 417-426, 2016 | 70 | 2016 |
Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense X Li, XX Tang, LG Vargas Buonfiglio, AP Comellas, IM Thornell, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 310 (7 …, 2016 | 50 | 2016 |
Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor EH Chang, XX Tang, VS Shah, JL Launspach, SE Ernst, B Hilkin, PH Karp, ... International forum of allergy & rhinology 5 (2), 178-181, 2015 | 50 | 2015 |
Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth L Paemka, BN McCullagh, MH Abou Alaiwa, DA Stoltz, Q Dong, ... Journal of Cystic Fibrosis 16 (4), 471-474, 2017 | 44 | 2017 |
Mucus strands from submucosal glands initiate mucociliary transport of large particles AJ Fischer, MI Pino-Argumedo, BM Hilkin, CR Shanrock, ND Gansemer, ... JCI insight 4 (1), 2019 | 43 | 2019 |
Effects of coal fly ash particulate matter on the antimicrobial activity of airway surface liquid LG Vargas Buonfiglio, IA Mudunkotuwa, MH Abou Alaiwa, ... Environmental health perspectives 125 (7), 077003, 2017 | 40 | 2017 |
Repurposing tromethamine as inhaled therapy to treat CF airway disease MH Abou Alaiwa, JL Launspach, KA Sheets, JA Rivera, ND Gansemer, ... JCI insight 1 (8), 2016 | 39 | 2016 |
Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling S Mao, AS Shah, TO Moninger, LS Ostedgaard, L Lu, XX Tang, ... Proceedings of the National Academy of Sciences 115 (6), 1370-1375, 2018 | 33 | 2018 |
Early airway structural changes in cystic fibrosis pigs as a determinant of particle distribution and deposition M Awadalla, S Miyawaki, MH Abou Alaiwa, RJ Adam, DC Bouzek, ... Annals of biomedical engineering 42, 915-927, 2014 | 31 | 2014 |
Lack of airway submucosal glands impairs respiratory host defenses LS Ostedgaard, MP Price, KM Whitworth, MH Abou Alaiwa, AJ Fischer, ... Elife 9, e59653, 2020 | 30 | 2020 |