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Hannes Mikula
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Nano-palladium is a cellular catalyst for in vivo chemistry.
MA Miller, B Askevold, H Mikula, RH Kohler, D Pirovich, R Weissleder
Nature Communications 8, 15906, 2017
2502017
Unraveling tetrazine-triggered bioorthogonal elimination enables chemical tools for ultrafast release and universal cleavage
JCT Carlson, H Mikula, R Weissleder
Journal of the American Chemical Society 140 (10), 3603-3612, 2018
1702018
Development and validation of a rapid multi‐biomarker liquid chromatography/tandem mass spectrometry method to assess human exposure to mycotoxins
B Warth, M Sulyok, P Fruhmann, H Mikula, F Berthiller, R Schuhmacher, ...
Rapid Communications in Mass Spectrometry 26 (13), 1533-1540, 2012
1512012
Development of a 18F‐Labeled Tetrazine with Favorable Pharmacokinetics for Bioorthogonal PET Imaging
C Denk, D Svatunek, T Filip, T Wanek, D Lumpi, J Fröhlich, C Kuntner, ...
Angewandte Chemie International Edition 53 (36), 9655-9659, 2014
1302014
Tracking emerging mycotoxins in food: development of an LC-MS/MS method for free and modified Alternaria toxins
H Puntscher, ML Kütt, P Skrinjar, H Mikula, J Podlech, J Fröhlich, D Marko, ...
Analytical and bioanalytical chemistry 410, 4481-4494, 2018
1272018
Validated UPLC-MS/MS Methods To Quantitate Free and Conjugated Alternaria Toxins in Commercially Available Tomato Products and Fruit and Vegetable Juices …
J Walravens, H Mikula, M Rychlik, S Asam, T Devos, E Njumbe Ediage, ...
Journal of Agricultural and Food Chemistry 64 (24), 5101-5109, 2016
1152016
Development and validation of an ultra-high-performance liquid chromatography tandem mass spectrometric method for the simultaneous determination of free and conjugated …
J Walravens, H Mikula, M Rychlik, S Asam, EN Ediage, JD Di Mavungu, ...
Journal of Chromatography A 1372, 91-101, 2014
1102014
Design, Synthesis, and Evaluation of a Low-Molecular-Weight 11C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry
C Denk, D Svatunek, S Mairinger, J Stanek, T Filip, D Matscheko, ...
Bioconjugate Chemistry 27 (7), 1707-1712, 2016
912016
Glucuronidation of zearalenone, zeranol and four metabolites in vitro: Formation of glucuronides by various microsomes and human UDP‐glucuronosyltransferase …
E Pfeiffer, A Hildebrand, H Mikula, M Metzler
Molecular nutrition & food research 54 (10), 1468-1476, 2010
902010
Modular nanoparticulate prodrug design enables efficient treatment of solid tumors using bioorthogonal activation
MA Miller, H Mikula, G Luthria, R Li, S Kronister, M Prytyskach, RH Kohler, ...
ACS nano 12 (12), 12814-12826, 2018
872018
Practical and efficient large-scale preparation of dimethyldioxirane
H Mikula, D Svatunek, D Lumpi, F Glöcklhofer, C Hametner, J Fröhlich
Organic Process Research & Development 17 (2), 313-316, 2013
712013
Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer
R Li, TSC Ng, SJ Wang, M Prytyskach, CB Rodell, H Mikula, RH Kohler, ...
Nature nanotechnology 16 (7), 830-839, 2021
702021
Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging
EJL Stéen, JT Jørgensen, K Johann, K Nørregaard, B Sohr, D Svatunek, ...
ACS nano 14 (1), 568-584, 2019
702019
Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry
EJL Stéen, JT Jørgensen, C Denk, UM Battisti, K Nørregaard, PE Edem, ...
ACS pharmacology & translational science 4 (2), 824-833, 2021
662021
Optimized near-IR fluorescent agents for in vivo imaging of Btk expression
E Kim, KS Yang, RH Kohler, JM Dubach, H Mikula, R Weissleder
Bioconjugate chemistry 26 (8), 1513-1518, 2015
632015
An integrated in silico/in vitro approach to assess the xenoestrogenic potential of Alternaria mycotoxins and metabolites
L Dellafiora, B Warth, V Schmidt, G Del Favero, H Mikula, J Fröhlich, ...
Food chemistry 248, 253-261, 2018
602018
Chemoselectivity of Tertiary Azides in Strain‐Promoted Alkyne‐Azide Cycloadditions
D Svatunek, N Houszka, TA Hamlin, FM Bickelhaupt, H Mikula
Chemistry–A European Journal 25 (3), 754-758, 2019
552019
Uncovering the key role of distortion in bioorthogonal tetrazine tools that defy the reactivity/stability trade-off
D Svatunek, M Wilkovitsch, L Hartmann, KN Houk, H Mikula
Journal of the American Chemical Society 144 (18), 8171-8177, 2022
502022
Direct Cu-mediated aromatic 18 F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging
R García-Vázquez, UM Battisti, JT Jørgensen, V Shalgunov, L Hvass, ...
Chemical science 12 (35), 11668-11675, 2021
492021
A Cleavable C2-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes
M Wilkovitsch, M Haider, B Sohr, B Herrmann, J Klubnick, R Weissleder, ...
Journal of the American Chemical Society 142 (45), 19132-19141, 2020
452020
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