| CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours RC Larson, MC Kann, SR Bailey, NJ Haradhvala, PM Llopis, AA Bouffard, ... Nature 604 (7906), 563-570, 2022 | 257 | 2022 |
| Reversible ON-and OFF-switch chimeric antigen receptors controlled by lenalidomide M Jan, I Scarfò, RC Larson, A Walker, A Schmidts, AA Guirguis, JA Gasser, ... Science translational medicine 13 (575), eabb6295, 2021 | 212 | 2021 |
| Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma NJ Haradhvala, MB Leick, K Maurer, SH Gohil, RC Larson, N Yao, ... Nature medicine 28 (9), 1848-1859, 2022 | 146 | 2022 |
| Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia MB Leick, H Silva, I Scarfò, R Larson, BD Choi, AA Bouffard, K Gallagher, ... Cancer cell 40 (5), 494-508. e5, 2022 | 91 | 2022 |
| Blockade or deletion of IFNγ reduces macrophage activation without compromising CAR T-cell function in hematologic malignancies SR Bailey, S Vatsa, RC Larson, AA Bouffard, I Scarfò, MC Kann, ... Blood Cancer Discovery 3 (2), 136-153, 2022 | 90 | 2022 |
| Tandem chimeric antigen receptor (CAR) T cells targeting EGFRvIII and IL-13Rα2 are effective against heterogeneous glioblastoma A Schmidts, AA Srivastava, R Ramapriyan, SR Bailey, AA Bouffard, ... Neuro-Oncology Advances 5 (1), vdac185, 2023 | 33 | 2023 |
| Evaluation of serological lateral flow assays for severe acute respiratory syndrome coronavirus-2 BA Trombetta, SE Kandigian, RR Kitchen, K Grauwet, PK Webb, GA Miller, ... BMC infectious diseases 21 (1), 580, 2021 | 27 | 2021 |
| Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources A Schmidts, LC Marsh, AA Srivastava, AA Bouffard, AC Boroughs, I Scarfò, ... Journal for immunotherapy of cancer 8 (2), 2020 | 23 | 2020 |
| Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma M Wehrli, S Guinn, F Birocchi, A Kuo, Y Sun, RC Larson, AJ Almazan, ... Clinical Cancer Research 30 (9), 1859-1877, 2024 | 17 | 2024 |
| Anti-TACI single and dual-targeting CAR T cells overcome BCMA antigen loss in multiple myeloma RC Larson, MC Kann, C Graham, CW Mount, AP Castano, WH Lee, ... Nature Communications 14 (1), 7509, 2023 | 16 | 2023 |
| Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics F Korell, ML Olson, D Salas-Benito, MB Leick, RC Larson, A Bouffard, ... Science Translational Medicine 16 (750), eadk7640, 2024 | 6 | 2024 |
| Genetic retargeting of E3 ligases to enhance CAR T cell therapy IC Lane, G Kembuan, J Carreiro, MC Kann, W Lin, AA Bouffard, J Kreuzer, ... Cell Chemical Biology 31 (2), 338-348. e5, 2024 | 6 | 2024 |
| Stealth transgenes enable CAR-T cells to evade host immune responses K Grauwet, T Berger, MC Kann, H Silva, R Larson, MB Leick, SR Bailey, ... Journal for Immunotherapy of Cancer 12 (5), 2024 | 4 | 2024 |
| Effects of prior exposure to Tec kinase (BTK/ITK) inhibitors on Kte-X19 products I Scarfò, KME Gallagher, MB Leick, MC Kann, J Budka, B Sowrirajan, ... Blood 138, 3849, 2021 | 4 | 2021 |
| Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7 MC Kann, EM Schneider, AJ Almazan, IC Lane, AA Bouffard, VM Supper, ... Leukemia 38 (3), 590-600, 2024 | 3 | 2024 |
| Novel anti-TACI single and dual-targeting CAR T cells overcome BCMA antigen loss in multiple myeloma RC Larson, A Castano, AA Bouffard, MC Kann, A Schmidts, KM Gallagher, ... Cancer Research 82 (12_Supplement), 556-556, 2022 | 3 | 2022 |
| Rational chemical and genetic modifications enhance avidity and function of CD70-directed CAR-T-cells for myeloid leukemia MB Leick, H Silva, I Scarfò, R Larson, BD Choi, AA Bouffard, ... Blood 138, 405, 2021 | 3 | 2021 |
| Bispecific CAR T cells for multiple myeloma: natural ligand compared to tandem scFv design R Larson, A Castano, A Bouffard, I Scarfo, M Kann, A Schmidts, ... The Journal of Immunology 204 (1_Supplement), 246.3-246.3, 2020 | 2 | 2020 |
| Chimeric antigen receptor (CAR) T cells overexpressing Bcl-xL increase proliferation and antitumor activity alone and in combination with BH3 mimetics F Korell, M Olson, D Salas-Benito, MB Leick, RC Larson, H Silva, ... Cancer Research 83 (7_Supplement), 4098-4098, 2023 | 1 | 2023 |
| 767 interferon gamma reduces CAR-T exhaustion and toxicity without compromising therapeutic efficacy in hematologic malignancies S Bailey, S Vatsa, A Bouffard, R Larson, I Scarfo, M Kann, A Schmidts, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 1 | 2020 |
