CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment SY Neo, Y Yang, J Record, R Ma, X Chen, Z Chen, NP Tobin, E Blake, ... The Journal of clinical investigation 130 (3), 1185-1198, 2020 | 173 | 2020 |
Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein–Barr virus SA Kamranvar, X Chen, MG Masucci Oncogene 32 (49), 5522-5530, 2013 | 65 | 2013 |
Caspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells S Gastaldello, X Chen, S Callegari, MG Masucci PLoS pathogens 9 (10), e1003664, 2013 | 51 | 2013 |
Oxidative stress enables Epstein–Barr virus-induced B-cell transformation by posttranscriptional regulation of viral and cellular growth-promoting factors X Chen, SA Kamranvar, MG Masucci Oncogene 35 (29), 3807-3816, 2016 | 50 | 2016 |
Solid-phase capture and profiling of open chromatin by spatial ATAC E Llorens-Bobadilla, M Zamboni, M Marklund, N Bhalla, X Chen, ... Nature Biotechnology 41 (8), 1085-1088, 2023 | 32 | 2023 |
The importance of sex in the discovery of colorectal cancer prognostic biomarkers L Hases, A Ibrahim, X Chen, Y Liu, J Hartman, C Williams International journal of molecular sciences 22 (3), 1354, 2021 | 22 | 2021 |
Spatial transcriptomics of B cell and T cell receptors reveals lymphocyte clonal dynamics C Engblom, K Thrane, Q Lin, A Andersson, H Toosi, X Chen, E Steiner, ... Science 382 (6675), eadf8486, 2023 | 20 | 2023 |
Thermal proteome profiling identifies oxidative-dependent inhibition of the transcription of major oncogenes as a new therapeutic mechanism for select anticancer compounds S Peuget, J Zhu, G Sanz, M Singh, M Gaetani, X Chen, Y Shi, AA Saei, ... Cancer research 80 (7), 1538-1550, 2020 | 18 | 2020 |
Tumor viruses and replicative immortality–avoiding the telomere hurdle X Chen, SA Kamranvar, MG Masucci Seminars in cancer biology 26, 43-51, 2014 | 17 | 2014 |
Identification and targeting of selective vulnerability rendered by tamoxifen resistance M Singh, X Zhou, X Chen, GS Santos, S Peuget, Q Cheng, A Rihani, ... Breast Cancer Research 22, 1-16, 2020 | 15 | 2020 |
A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models AHM Tay, R Prieto-Díaz, S Neo, L Tong, X Chen, V Carannante, B Önfelt, ... Journal for Immunotherapy of Cancer 10 (5), 2022 | 14 | 2022 |
Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction X Chen, EG Sifakis, S Robertson, SY Neo, SH Jun, L Tong, AT Hui Min, ... Proceedings of the National Academy of Sciences 120 (1), e2209856120, 2023 | 6 | 2023 |
Reconstructing clonal tree for phylo-phenotypic characterization of cancer using single-cell transcriptomics SH Jun, H Toosi, J Mold, C Engblom, X Chen, C O’Flanagan, ... Nature Communications 14 (1), 982, 2023 | 5 | 2023 |
Spatial transcriptomics of T and B cell receptors uncovers lymphocyte clonal dynamics in human tissue C Engblom, K Thrane, Q Lin, A Andersson, H Toosi, X Chen, E Steiner, ... BioRxiv, 2022.11. 22.516865, 2022 | 4 | 2022 |
Prognostic impact of HER2 biomarker levels in trastuzumab-treated early HER2-positive breast cancer C Rönnlund, EG Sifakis, C Schagerholm, Q Yang, E Karlsson, X Chen, ... Breast Cancer Research 26 (1), 24, 2024 | 3 | 2024 |
Chromatin accessibility profiling in tissue sections by spatial ATAC E Llorens-Bobadilla, M Zamboni, M Marklund, N Bhalla, X Chen, ... bioRxiv, 2022.07. 27.500203, 2022 | 3 | 2022 |
Development and characterization of a recombinant silk network for 3D culture of immortalized and fresh tumor‐derived breast cancer cells C Collodet, K Blust, S Gkouma, E Ståhl, X Chen, J Hartman, ... Bioengineering & Translational Medicine 8 (5), e10537, 2023 | 2 | 2023 |
Renal cell carcinoma escapes NK cell‐mediated immune surveillance through the downregulation of DNAM‐1 L Tong, V Kremer, SY Neo, Y Liu, Y Chen, AK Wagner, Y Yang, Z Chen, ... Cancer Communications 43 (7), 855, 2023 | 2 | 2023 |
PhylEx: Accurate reconstruction of clonal structure via integrated analysis of bulk DNA-seq and single cell RNA-seq data SH Jun, H Toosi, J Mold, C Engblom, X Chen, C O’Flanagan, ... bioRxiv, 2021.02. 16.431009, 2021 | 2 | 2021 |
The importance of sex in colorectal cancer biomarker discovery L Hases, A Ibrahim, M Birgersson, Y Liu, X Chen, J Hartman, C Williams | 1 | 2020 |