| Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain V Baud, ZG Liu, B Bennett, N Suzuki, Y Xia, M Karin Genes & development 13 (10), 1297-1308, 1999 | 624 | 1999 |
| Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch M Gao, T Labuda, Y Xia, E Gallagher, D Fang, YC Liu, M Karin Science 306 (5694), 271-275, 2004 | 487 | 2004 |
| MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration Y Xia, C Makris, B Su, E Li, J Yang, GR Nemerow, M Karin Proceedings of the National Academy of Sciences 97 (10), 5243-5248, 2000 | 371 | 2000 |
| Calcineurin preferentially synergizes with PKC‐θ to activate JNK and IL‐2 promoter in T lymphocytes G Werlen, E Jacinto, Y Xia, M Karin The EMBO journal, 1998 | 343 | 1998 |
| Role of the aryl hydrocarbon receptor in cell cycle regulation A Puga, Y Xia, C Elferink Chemico-biological interactions 141 (1-2), 117-130, 2002 | 325 | 2002 |
| The control of cell motility and epithelial morphogenesis by Jun kinases Y Xia, M Karin Trends in cell biology 14 (2), 94-101, 2004 | 291 | 2004 |
| c-Jun, at the crossroad of the signaling network Q Meng, Y Xia Protein & cell 2 (11), 889-898, 2011 | 269 | 2011 |
| Cocaine-induced intracellular signaling and gene expression are oppositely regulated by the dopamine D1 and D3 receptors L Zhang, D Lou, H Jiao, D Zhang, X Wang, Y Xia, J Zhang, M Xu Journal of Neuroscience 24 (13), 3344-3354, 2004 | 259 | 2004 |
| JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension Y Xia, Z Wu, B Su, B Murray, M Karin Genes & development 12 (21), 3369-3381, 1998 | 253 | 1998 |
| c‐Jun N‐terminal kinases (JNK) antagonize cardiac growth through cross‐talk with calcineurin–NFAT signaling Q Liang, OF Bueno, BJ Wilkins, CY Kuan, Y Xia, JD Molkentin The EMBO journal, 2003 | 251 | 2003 |
| TAL2, a helix-loop-helix gene activated by the (7; 9)(q34; q32) translocation in human T-cell leukemia. Y Xia, L Brown, CY Yang, JT Tsan, MJ Siciliano, R Espinosa III, ... Proceedings of the National Academy of Sciences 88 (24), 11416-11420, 1991 | 234 | 1991 |
| Activation of mitogen-activated protein kinases (MAPKs) by aromatic hydrocarbons: role in the regulation of aryl hydrocarbon receptor (AHR) function Z Tan, X Chang, A Puga, Y Xia Biochemical pharmacology 64 (5-6), 771-780, 2002 | 223 | 2002 |
| A role for MEK kinase 1 in TGF‐β/activin‐induced epithelium movement and embryonic eyelid closure L Zhang, W Wang, Y Hayashi, JV Jester, DE Birk, M Gao, CY Liu, ... The EMBO journal, 2003 | 211 | 2003 |
| Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic β cells S Khoo, SC Griffen, Y Xia, RJ Baer, MS German, MH Cobb Journal of Biological Chemistry 278 (35), 32969-32977, 2003 | 209 | 2003 |
| Ah receptor signals cross-talk with multiple developmental pathways A Puga, CR Tomlinson, Y Xia Biochemical pharmacology 69 (2), 199-207, 2005 | 202 | 2005 |
| The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis Y Fan, GP Boivin, ES Knudsen, DW Nebert, Y Xia, A Puga Cancer research 70 (1), 212-220, 2010 | 200 | 2010 |
| Epigenetics as a mechanism linking developmental exposures to long-term toxicity R Barouki, E Melén, Z Herceg, J Beckers, J Chen, M Karagas, A Puga, ... Environment international 114, 77-86, 2018 | 180 | 2018 |
| The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis JL Marlowe, Y Fan, X Chang, L Peng, ES Knudsen, Y Xia, A Puga Molecular biology of the cell 19 (8), 3263-3271, 2008 | 144 | 2008 |
| MEKK1 transduces activin signals in keratinocytes to induce actin stress fiber formation and migration L Zhang, M Deng, R Parthasarathy, L Wang, M Mongan, JD Molkentin, ... Molecular and cellular biology 25 (1), 60-65, 2005 | 128 | 2005 |
| MEKK1 plays a critical role in activating the transcription factor C/EBP-β-dependent gene expression in response to IFN-γ SK Roy, J Hu, Q Meng, Y Xia, PS Shapiro, SPM Reddy, LC Platanias, ... Proceedings of the National Academy of Sciences 99 (12), 7945-7950, 2002 | 127 | 2002 |
