11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess SA Morgan, EL McCabe, LL Gathercole, ZK Hassan-Smith, DP Larner, ... Proceedings of the National Academy of Sciences 111 (24), E2482-E2491, 2014 | 290 | 2014 |
11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects LL Gathercole, GG Lavery, SA Morgan, MS Cooper, AJ Sinclair, ... Endocrine reviews 34 (4), 525-555, 2013 | 210 | 2013 |
11β-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle SA Morgan, M Sherlock, LL Gathercole, GG Lavery, C Lenaghan, ... Diabetes 58 (11), 2506-2515, 2009 | 202 | 2009 |
Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue LL Gathercole, SA Morgan, IJ Bujalska, D Hauton, PM Stewart, ... PloS one 6 (10), e26223, 2011 | 180 | 2011 |
11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects A Tiganescu, AA Tahrani, SA Morgan, M Otranto, A Desmoulière, ... The Journal of clinical investigation 123 (7), 3051-3060, 2013 | 138 | 2013 |
Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice JK Dowman, LJ Hopkins, GM Reynolds, MJ Armstrong, M Nasiri, ... Endocrinology 154 (12), 4536-4547, 2013 | 96 | 2013 |
25-hydroxyvitamin D3 and 1, 25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression ZK Hassan-Smith, C Jenkinson, DJ Smith, I Hernandez, SA Morgan, ... PloS one 12 (2), e0170665, 2017 | 88 | 2017 |
Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1 GG Lavery, AE Zielinska, LL Gathercole, B Hughes, N Semjonous, ... Endocrinology 153 (7), 3236-3248, 2012 | 83 | 2012 |
Gender-specific differences in skeletal muscle 11β-HSD1 expression across healthy aging ZK Hassan-Smith, SA Morgan, M Sherlock, B Hughes, AE Taylor, ... The Journal of Clinical Endocrinology & Metabolism 100 (7), 2673-2681, 2015 | 79 | 2015 |
Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells MM Ahasan, R Hardy, C Jones, K Kaur, D Nanus, M Juarez, SA Morgan, ... Arthritis & Rheumatism 64 (7), 2404-2413, 2012 | 59 | 2012 |
11β-Hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes SA Morgan, JW Tomlinson Expert opinion on investigational drugs 19 (9), 1067-1076, 2010 | 57 | 2010 |
Long-term effectiveness of adjuvant treatment with catechol-O-methyltransferase or monoamine oxidase B inhibitors compared with dopamine agonists among patients with Parkinson … R Gray, S Patel, N Ives, C Rick, R Woolley, S Muzerengi, A Gray, ... JAMA neurology 79 (2), 131-140, 2022 | 52 | 2022 |
Mechanisms in endocrinology: tissue-specific activation of cortisol in Cushing's syndrome SA Morgan, ZK Hassan-Smith, GG Lavery European journal of endocrinology 175 (2), R81-R87, 2016 | 43 | 2016 |
Enhanced anxiety-like behavior emerges with weight gain in male and female obesity-susceptible rats Y Alonso-Caraballo, KJ Hodgson, SA Morgan, CR Ferrario, PJ Vollbrecht Behavioural brain research 360, 81-93, 2019 | 41 | 2019 |
Regulation of lipid metabolism by glucocorticoids and 11β-HSD1 in skeletal muscle SA Morgan, LL Gathercole, C Simonet, ZK Hassan-Smith, I Bujalska, ... Endocrinology 154 (7), 2374-2384, 2013 | 39 | 2013 |
11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice CL Doig, RS Fletcher, SA Morgan, EL McCabe, DP Larner, JW Tomlinson, ... Endocrinology 158 (6), 1964-1976, 2017 | 38 | 2017 |
Hormonal regulation of lipogenesis LL Gathercole, SA Morgan, JW Tomlinson Vitamins & hormones 91, 1-27, 2013 | 37 | 2013 |
Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism SA Morgan, ZK Hassan-Smith, CL Doig, M Sherlock, PM Stewart, ... The Journal of Endocrinology 229 (3), 277, 2016 | 34 | 2016 |
11β‐Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation RS Hardy, CL Doig, Z Hussain, M O'Leary, SA Morgan, MJ Pearson, ... The Journal of pathology 240 (4), 472-483, 2016 | 33 | 2016 |
Male 11β-HSD1 knockout mice fed trans-fats and fructose are not protected from metabolic syndrome or nonalcoholic fatty liver disease DP Larner, SA Morgan, LL Gathercole, CL Doig, P Guest, C Weston, ... Endocrinology 157 (9), 3493-3504, 2016 | 27 | 2016 |