Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche T Sato, RG Vries, HJ Snippert, M Van De Wetering, N Barker, DE Stange, ... Nature 459 (7244), 262-265, 2009 | 6873 | 2009 |
Identification of stem cells in small intestine and colon by marker gene Lgr5 N Barker, JH Van Es, J Kuipers, P Kujala, M Van Den Born, M Cozijnsen, ... Nature 449 (7165), 1003-1007, 2007 | 6267 | 2007 |
Lgr5+ ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro N Barker, M Huch, P Kujala, M van de Wetering, HJ Snippert, JH van Es, ... Cell stem cell 6 (1), 25-36, 2010 | 1751 | 2010 |
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ... Nature 476 (7360), 293-297, 2011 | 1405 | 2011 |
Transcription factor achaete scute-like 2 controls intestinal stem cell fate LG van der Flier, ME van Gijn, P Hatzis, P Kujala, A Haegebarth, ... Cell 136 (5), 903-912, 2009 | 811 | 2009 |
In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection S Bartfeld, T Bayram, M van de Wetering, M Huch, H Begthel, P Kujala, ... Gastroenterology 148 (1), 126-136. e6, 2015 | 780 | 2015 |
Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium DE Stange, BK Koo, M Huch, G Sibbel, O Basak, A Lyubimova, P Kujala, ... Cell 155 (2), 357-368, 2013 | 536 | 2013 |
Sunday Driver links axonal transport to damage signaling V Cavalli, P Kujala, J Klumperman, LSB Goldstein The Journal of cell biology 168 (5), 775-787, 2005 | 341 | 2005 |
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal JH van Es, A Haegebarth, P Kujala, S Itzkovitz, BK Koo, SF Boj, J Korving, ... Molecular and cellular biology, 2012 | 303 | 2012 |
Biogenesis of the Semliki Forest virus RNA replication complex P Kujala, A Ikäheimonen, N Ehsani, H Vihinen, P Auvinen, ... Journal of virology 75 (8), 3873-3884, 2001 | 299 | 2001 |
Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell–derived IFN-γ HF Farin, WR Karthaus, P Kujala, M Rakhshandehroo, G Schwank, ... Journal of Experimental Medicine 211 (7), 1393-1405, 2014 | 289 | 2014 |
The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium A Gregorieff, DE Stange, P Kujala, H Begthel, M Van den Born, J Korving, ... Gastroenterology 137 (4), 1333-1345. e3, 2009 | 279 | 2009 |
Peyer's patch M cells derived from Lgr5+ stem cells require SpiB and are induced by RankL in cultured “miniguts” W de Lau, P Kujala, K Schneeberger, S Middendorp, VSW Li, N Barker, ... Molecular and cellular biology, 2012 | 266 | 2012 |
Lgr5+ ve stem/progenitor cells contribute to nephron formation during kidney development N Barker, MB Rookmaaker, P Kujala, A Ng, M Leushacke, H Snippert, ... Cell reports 2 (3), 540-552, 2012 | 255 | 2012 |
The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders A Andrieux, PA Salin, M Vernet, P Kujala, J Baratier, S Gory-Fauré, ... Genes & development 16 (18), 2350-2364, 2002 | 216 | 2002 |
CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling Q Yan, W Sun, P Kujala, Y Lotfi, TA Vida, AJ Bean Molecular biology of the cell 16 (5), 2470-2482, 2005 | 152 | 2005 |
Prion uptake in the gut: identification of the first uptake and replication sites P Kujala, CR Raymond, M Romeijn, SF Godsave, SI van Kasteren, ... PLoS Pathogens 7 (12), e1002449, 2011 | 142 | 2011 |
Intestinal epithelial organoids fuse to form self-organizing tubes in floating collagen gels N Sachs, Y Tsukamoto, P Kujala, PJ Peters, H Clevers Development 144 (6), 1107-1112, 2017 | 129 | 2017 |
The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM CC Yap, D Wisco, P Kujala, ZM Lasiecka, JT Cannon, MC Chang, ... The Journal of cell biology 180 (4), 827-842, 2008 | 125 | 2008 |
Effects of palmitoylation of replicase protein nsP1 on alphavirus infection T Ahola, P Kujala, M Tuittila, T Blom, P Laakkonen, A Hinkkanen, ... Journal of virology 74 (15), 6725-6733, 2000 | 124 | 2000 |