Organoid modeling of the tumor immune microenvironment JT Neal, X Li, J Zhu, V Giangarra, CL Grzeskowiak, J Ju, IH Liu, SH Chiou, ... Cell 175 (7), 1972-1988. e16, 2018 | 1132 | 2018 |
The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations KS Yan, LA Chia, X Li, A Ootani, J Su, JY Lee, N Su, Y Luo, SC Heilshorn, ... Proceedings of the National Academy of Sciences 109 (2), 466-471, 2012 | 975 | 2012 |
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche A Ootani, X Li, E Sangiorgi, QT Ho, H Ueno, S Toda, H Sugihara, ... Nature medicine 15 (6), 701-706, 2009 | 936 | 2009 |
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis J Rosenbluh, D Nijhawan, AG Cox, X Li, JT Neal, EJ Schafer, TI Zack, ... Cell 151 (7), 1457-1473, 2012 | 824 | 2012 |
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture X Li, L Nadauld, A Ootani, DC Corney, RK Pai, O Gevaert, MA Cantrell, ... Nature medicine 20 (7), 769-777, 2014 | 435 | 2014 |
Controlling epithelial polarity: a human enteroid model for host-pathogen interactions M Margalef-Català, X Li, AT Mah, CJ Kuo, DM Monack, MR Amieva Cell reports 26 (9), 2509-2520. e4, 2019 | 364 | 2019 |
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling CY Janda, LT Dang, C You, J Chang, W De Lau, ZA Zhong, KS Yan, ... Nature 545 (7653), 234-237, 2017 | 326 | 2017 |
Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation X Li, W Deng, CD Nail, SK Bailey, MH Kraus, JM Ruppert, ... Oncogene 25 (4), 609-621, 2006 | 234 | 2006 |
Induction of KLF4 in basal keratinocytes blocks the proliferation–differentiation switch and initiates squamous epithelial dysplasia KW Foster, Z Liu, CD Nail, X Li, TJ Fitzgerald, SK Bailey, AR Frost, ... Oncogene 24 (9), 1491-1500, 2005 | 227 | 2005 |
Gli1 acts through Snail and E-cadherin to promote nuclear signaling by β-catenin X Li, W Deng, SM Lobo-Ruppert, JM Ruppert Oncogene 26 (31), 4489-4498, 2007 | 184 | 2007 |
Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation ID Louro, EC Bailey, X Li, LS South, PR McKie-Bell, BK Yoder, CC Huang, ... Cancer research 62 (20), 5867-5873, 2002 | 154 | 2002 |
KLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasia CC Huang, Z Liu, X Li, S Bailey, CD Nail, KW Foster, AR Frost, ... Cancer biology & therapy 4 (12), 1401-1408, 2005 | 102 | 2005 |
An air–liquid interface culture system for 3D organoid culture of diverse primary gastrointestinal tissues X Li, A Ootani, C Kuo Gastrointestinal Physiology and Diseases: Methods and Protocols, 33-40, 2016 | 99 | 2016 |
Development of a miniaturized 3D organoid culture platform for ultra-high-throughput screening Y Du, X Li, Q Niu, X Mo, M Qui, T Ma, CJ Kuo, H Fu Journal of Molecular Cell Biology 12 (8), 630-643, 2020 | 82 | 2020 |
STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection S Ding, J Diep, N Feng, L Ren, B Li, YS Ooi, X Wang, KF Brulois, ... Nature communications 9 (1), 1485, 2018 | 70 | 2018 |
Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling VC Luca, Y Miao, X Li, MJ Hollander, CJ Kuo, KC Garcia PloS one 15 (1), e0226928, 2020 | 19 | 2020 |
Gastrointestinal organoid cultures for functional evaluation of oncogenic loci. AA Salahudeen, X Li, M Cantrell, CJ Kuo Journal of Clinical Oncology 33 (3_suppl), 85-85, 2015 | 4 | 2015 |