NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase O Nidai Ozes, LD Mayo, JA Gustin, SR Pfeffer, LM Pfeffer, DB Donner Nature 401, 82-85, 1999 | 2759 | 1999 |
A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus LD Mayo, DB Donner Science's STKE 98 (20), 11598, 2001 | 1604 | 2001 |
The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network LD Mayo, DB Donner Trends in biochemical sciences 27 (9), 462-467, 2002 | 576 | 2002 |
A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1 ON Ozes, H Akca, LD Mayo, JA Gustin, T Maehama, JE Dixon, DB Donner Proceedings of the National Academy of Sciences 98 (8), 4640, 2001 | 514 | 2001 |
PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy LD Mayo, JE Dixon, DL Durden, NK Tonks, DB Donner Journal of Biological Chemistry 277 (7), 5484-5489, 2002 | 480 | 2002 |
Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation LW Wu, LD Mayo, JD Dunbar, KM Kessler, MR Baerwald, EA Jaffe, ... Journal of Biological Chemistry 275 (7), 5096-5103, 2000 | 366 | 2000 |
Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53 LD Mayo, JJ Turchi, SJ Berberich Cancer research 57 (22), 5013, 1997 | 339 | 1997 |
Cell type specific expression of the IkB kinases determines the significance of PI 3-kinase/Akt signaling to NF-kB activation JA Gustin, ON Ozes, H Akca, R Pincheira, L Mayo, Q Li, J Rivera Guzman, ... Journal of Biological Chemistry, 2003 | 269* | 2003 |
Levels of HdmX expression dictate the sensitivity of normal and transformed cells to Nutlin-3 JT Patton, LD Mayo, AD Singhi, AV Gudkov, GR Stark, MW Jackson Cancer research 66 (6), 3169-3176, 2006 | 235 | 2006 |
Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified LD Mayo, YR Seo, MW Jackson, ML Smith, JR Guzman, CK Korgaonkar, ... Journal of Biological Chemistry 280 (28), 25953-25959, 2005 | 202 | 2005 |
Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor T Criswell, M Beman, S Araki, K Leskov, E Cataldo, LD Mayo, ... Journal of Biological Chemistry 280 (14), 14212-14221, 2005 | 186 | 2005 |
PTEN and Phosphatidylinositol 3′-Kinase Inhibitors Up-Regulate p53 and Block Tumor-induced Angiogenesis JD Su, LD Mayo, DB Donner, DL Durden Cancer research 63 (13), 3585, 2003 | 185 | 2003 |
Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain S Yadavilli, LD Mayo, M Higgins, S Lain, V Hegde, WA Deutsch DNA repair 8 (10), 1215-1224, 2009 | 179 | 2009 |
VRAP is an adaptor protein that binds KDR, a receptor for vascular endothelial cell growth factor LW Wu, LD Mayo, JD Dunbar, KM Kessler, ON Ozes, RS Warren, ... Journal of Biological Chemistry 275 (9), 6059-6062, 2000 | 163 | 2000 |
TGF-β1–induced expression of human Mdm2 correlates with late-stage metastatic breast cancer S Araki, JA Eitel, CN Batuello, K Bijangi-Vishehsaraei, XJ Xie, ... The Journal of clinical investigation 120 (1), 290-302, 2010 | 161 | 2010 |
Tumor necrosis factor employs a protein-tyrosine phosphatase to inhibit activation of KDR and vascular endothelial cell growth factor-induced endothelial cell proliferation DQ Guo, LW Wu, JD Dunbar, ON Ozes, LD Mayo, KM Kessler, JA Gustin, ... Journal of Biological Chemistry 275 (15), 11216, 2000 | 158 | 2000 |
IR-inducible clusterin gene expression: a protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects D Klokov, T Criswell, KS Leskov, S Araki, L Mayo, DA Boothman Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 568 (1 …, 2004 | 124 | 2004 |
Nutlin3 blocks vascular endothelial growth factor induction by preventing the interaction between hypoxia inducible factor 1α and Hdm2 GA LaRusch, MW Jackson, JD Dunbar, RS Warren, DB Donner, LD Mayo Cancer research 67 (2), 450, 2007 | 112 | 2007 |
Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway S Chen, Q Wang, H Yu, ML Capitano, S Vemula, SC Nabinger, R Gao, ... Nature communications 10 (1), 5649, 2019 | 96 | 2019 |
Vascular endothelial cell growth factor activates CRE-binding protein by signaling through the KDR receptor tyrosine kinase LD Mayo, KM Kessler, R Pincheira, RS Warren, DB Donner Journal of Biological Chemistry 276 (27), 25184-25189, 2001 | 93 | 2001 |