Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting A Naggi, B Casu, M Perez, G Torri, G Cassinelli, S Penco, C Pisano, ... Journal of Biological Chemistry 280 (13), 12103-12113, 2005 | 298 | 2005 |
Significance of heparanase in cancer and inflammation I Vlodavsky, P Beckhove, I Lerner, C Pisano, A Meirovitz, N Ilan, M Elkin Cancer microenvironment 5, 115-132, 2012 | 286 | 2012 |
SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis JP Ritchie, VC Ramani, Y Ren, A Naggi, G Torri, B Casu, S Penco, ... Clinical Cancer Research 17 (6), 1382-1393, 2011 | 284 | 2011 |
Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine C Pisano, G Pratesi, D Laccabue, F Zunino, P Lo Giudice, A Bellucci, ... Clinical Cancer Research 9 (15), 5756-5767, 2003 | 246 | 2003 |
Chromatin and microtubule organization during premeiotic, meiotic and early postmeiotic stages of Drosophila melanogaster spermatogenesis G Cenci, S Bonaccorsi, C Pisano, F Verni, M Gatti Journal of Cell Science 107 (12), 3521-3534, 1994 | 233 | 1994 |
Heparanase is essential for the development of diabetic nephropathy in mice N Gil, R Goldberg, T Neuman, M Garsen, E Zcharia, AM Rubinstein, ... Diabetes 61 (1), 208-216, 2012 | 222 | 2012 |
Development and therapeutic impact of HDAC6-selective inhibitors S Dallavalle, C Pisano, F Zunino Biochemical pharmacology 84 (6), 756-765, 2012 | 194 | 2012 |
Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity S Dallavalle, A Ferrari, B Biasotti, L Merlini, S Penco, G Gallo, M Marzi, ... Journal of medicinal chemistry 44 (20), 3264-3274, 2001 | 143 | 2001 |
Novel combretastatin analogues endowed with antitumor activity D Simoni, R Romagnoli, R Baruchello, R Rondanin, M Rizzi, MG Pavani, ... Journal of medicinal chemistry 49 (11), 3143-3152, 2006 | 137 | 2006 |
Novel camptothecin analogue (gimatecan)‐containing liposomes prepared by the ethanol injection method P Stano, S Bufali, C Pisano, F Bucci, M Barbarino, M Santaniello, ... Journal of liposome research 14 (1-2), 87-109, 2004 | 137 | 2004 |
Heparanase-mediated loss of nuclear syndecan-1 enhances histone acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotype A Purushothaman, DR Hurst, C Pisano, S Mizumoto, K Sugahara, ... Journal of Biological Chemistry 286 (35), 30377-30383, 2011 | 129 | 2011 |
The potential of heparanase as a therapeutic target in cancer C Pisano, I Vlodavsky, N Ilan, F Zunino Biochemical pharmacology 89 (1), 12-19, 2014 | 121 | 2014 |
A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line P Perego, M De Cesare, P De Isabella, N Carenini, G Beggiolin, ... Cancer research 61 (16), 6034-6037, 2001 | 114 | 2001 |
Potent integrin antagonists from a small library of RGD-including cyclic pseudopeptides L Belvisi, A Bernardi, A Checchia, L Manzoni, D Potenza, C Scolastico, ... Organic letters 3 (7), 1001-1004, 2001 | 114 | 2001 |
Y chromosome loops in Drosophila melanogaster. S Bonaccorsi, C Pisano, F Puoti, M Gatti Genetics 120 (4), 1015-1034, 1988 | 114 | 1988 |
Position effect variegation in Drosophila melanogaster: relationship between suppression effect and the amount of Y chromosome. P Dimitri, C Pisano Genetics 122 (4), 793-800, 1989 | 113 | 1989 |
Undersulfated and glycol-split heparins endowed with antiangiogenic activity B Casu, M Guerrini, S Guglieri, A Naggi, M Perez, G Torri, G Cassinelli, ... Journal of medicinal chemistry 47 (4), 838-848, 2004 | 110 | 2004 |
Short heparin sequences spaced by glycol-split uronate residues are antagonists of fibroblast growth factor 2 and angiogenesis inhibitors B Casu, M Guerrini, A Naggi, M Perez, G Torri, D Ribatti, P Carminati, ... Biochemistry 41 (33), 10519-10528, 2002 | 107 | 2002 |
Acetyl-L-carnitine prevents and reverts experimental chronic neurotoxicity induced by oxaliplatin, without altering its antitumor properties O Ghirardi, PL Giudice, C Pisano, M Vertechy, A Bellucci, L Vesci, ... Anticancer research 25 (4), 2681-2687, 2005 | 103 | 2005 |
Synthesis and in vitro antitumor activity of new 4, 5-dihydropyrazole derivatives C Congiu, V Onnis, L Vesci, M Castorina, C Pisano Bioorganic & medicinal chemistry 18 (17), 6238-6248, 2010 | 99 | 2010 |