Reductions of aliphatic and aromatic nitriles to primary amines with diisopropylaminoborane D Haddenham, L Pasumansky, J DeSoto, S Eagon, B Singaram The Journal of organic chemistry 74 (5), 1964-1970, 2009 | 129 | 2009 |
Reaction of InCl3 with Various Reducing Agents: InCl3–NaBH4-Mediated Reduction of Aromatic and Aliphatic Nitriles to Primary Amines JZ Saavedra, A Resendez, A Rovira, S Eagon, D Haddenham, ... The Journal of Organic Chemistry 77 (1), 221-228, 2012 | 83 | 2012 |
Microwave‐Assisted Synthesis of Tetrahydro‐β‐carbolines and β‐Carbolines S Eagon, MO Anderson European Journal of Organic Chemistry 2014 (8), 1653-1665, 2014 | 64 | 2014 |
Evaluation of consensus scoring methods for AutoDock Vina, smina and idock L Masters, S Eagon, M Heying Journal of Molecular Graphics and Modelling 96, 107532, 2020 | 61 | 2020 |
In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin AG Bayih, A Folefoc, AN Mohon, S Eagon, M Anderson, DR Pillai Malaria Journal 15, 1-11, 2016 | 46 | 2016 |
Lithium aminoborohydrides 17. Palladium catalyzed borylation of aryl iodides, bromides, and triflates with diisopropylaminoborane prepared from lithium diisopropylaminoborohydride D Haddenham, CL Bailey, C Vu, G Nepomuceno, S Eagon, ... Tetrahedron 67 (3), 576-583, 2011 | 41 | 2011 |
Mild and Expedient Asymmetric Reductions of α,β-Unsaturated Alkenyl and Alkynyl Ketones by TarB-NO2 and Mechanistic Investigations of Ketone Reduction S Eagon, C DeLieto, WJ McDonald, D Haddenham, J Saavedra, J Kim, ... The Journal of Organic Chemistry 75 (22), 7717-7725, 2010 | 36 | 2010 |
Enantioselective reduction of α-substituted ketones mediated by the boronate ester TarB-NO2 S Eagon, N Ball-Jones, D Haddenham, J Saavedra, C DeLieto, ... Tetrahedron Letters 51 (49), 6418-6421, 2010 | 31 | 2010 |
Asymmetric reductions using the chiral boronic ester TarB–H: a practical and inexpensive procedure for synthesizing chiral alcohols S Eagon, J Kim, K Yan, D Haddenham, B Singaram Tetrahedron Letters 48 (51), 9025-9029, 2007 | 31 | 2007 |
Microwave synthesis of 1-aryl-1H-pyrazole-5-amines N Everson, K Yniguez, L Loop, H Lazaro, B Belanger, G Koch, J Bach, ... Tetrahedron Letters 60 (1), 72-74, 2019 | 26 | 2019 |
Synthesis and Structure–Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-b]pyridines S Eagon, JT Hammill, M Sigal, KJ Ahn, JE Tryhorn, G Koch, B Belanger, ... Journal of Medicinal Chemistry 63 (20), 11902-11919, 2020 | 24 | 2020 |
Identification of potential Zika virus NS2B-NS3 protease inhibitors via docking, molecular dynamics and consensus scoring-based virtual screening LR Bowen, DJ Li, DT Nola, MO Anderson, M Heying, AT Groves, S Eagon Journal of Molecular Modeling 25, 1-10, 2019 | 16 | 2019 |
Antimalarial activity of tetrahydro-β-carbolines targeting the ATP binding pocket of the Plasmodium falciparum heat shock 90 protein S Eagon, JT Hammill, J Bach, N Everson, TA Sisley, MJ Walls, S Durham, ... Bioorganic & medicinal chemistry letters 30 (21), 127502, 2020 | 15 | 2020 |
Synthesis of β-carbolines via a silver-mediated oxidation of tetrahydro-β-carbolines SD Durham, B Sierra, MJ Gomez, JK Tran, MO Anderson, ... Tetrahedron Letters 58 (28), 2747-2750, 2017 | 13 | 2017 |
Reaction of Grignard reagents with diisopropyl-aminoborane. Synthesis of alkyl, aryl, heteroaryl and allyl boronic acids from organo (diisopropyl)-aminoborane by a simple … CL Bailey, CL Murphy, JW Clary, S Eagon, N Gould, B Singaram Heterocycles 86, 331-341, 2012 | 11 | 2012 |
Mild and practical reductions of prochiral ketones to chiral alcohols using the chiral boronic ester TarB-H S Eagon, J Kim, B Singaram Synthesis 2008 (23), 3874-3876, 2008 | 9 | 2008 |
Identification of Plasmodium falciparum heat shock 90 inhibitors via molecular docking N Everson, J Bach, JT Hammill, MO Falade, AL Rice, RK Guy, S Eagon Bioorganic & Medicinal Chemistry Letters 35, 127818, 2021 | 7 | 2021 |
Structure guided development of potent piperazine-derived hydroxamic acid inhibitors targeting falcilysin G Kahlon, R Lira, N Masvlov, E Pompa, N Brar, S Eagon, MO Anderson, ... Bioorganic & Medicinal Chemistry Letters 32, 127683, 2021 | 5 | 2021 |
Antimalarial activity of 2, 6-dibenzylidenecyclohexanone derivatives S Eagon, JT Hammill, K Fitzsimmons, N Sienko, B Nguyen, J Law, ... Bioorganic & Medicinal Chemistry Letters 47, 128216, 2021 | 4 | 2021 |
Synthesis and activity of β-carboline antimalarials targeting the Plasmodium falciparum heat shock 90 protein NK Viswanathan, ME Chirgwin, J Gibbs, BN Kalaj, S Durham, J Tran, ... Bioorganic & Medicinal Chemistry Letters 92, 129410, 2023 | 2 | 2023 |