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Lei Zhu
Lei Zhu
Research Scientist, Gladstone institutes, University of California at San Francisco
在 gladstone.ucsf.edu 的电子邮件经过验证
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Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model
PE Sanchez, L Zhu, L Verret, KA Vossel, AG Orr, JR Cirrito, N Devidze, ...
Proceedings of the National Academy of Sciences 109 (42), E2895-E2903, 2012
6652012
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks
MJ Rardin, W He, Y Nishida, JC Newman, C Carrico, SR Danielson, ...
Cell metabolism 18 (6), 920-933, 2013
6302013
Life extension factor klotho enhances cognition
DB Dubal, JS Yokoyama, L Zhu, L Broestl, K Worden, D Wang, VE Sturm, ...
Cell reports 7 (4), 1065-1076, 2014
3432014
Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice
DB Dubal, L Zhu, PE Sanchez, K Worden, L Broestl, E Johnson, K Ho, ...
Journal of Neuroscience 35 (6), 2358-2371, 2015
2082015
Cortical neurons lacking KCC2 expression show impaired regulation of intracellular chloride
L Zhu, D Lovinger, E Delpire
Journal of neurophysiology 93 (3), 1557-1568, 2005
1752005
Klotho controls the brain–immune system interface in the choroid plexus
L Zhu, LR Stein, D Kim, K Ho, GQ Yu, L Zhan, TE Larsson, L Mucke
Proceedings of the National Academy of Sciences 115 (48), E11388-E11396, 2018
1282018
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus
L Zhu, N Polley, GC Mathews, E Delpire
Epilepsy research 79 (2-3), 201-212, 2008
1162008
Arf4 determines dentate gyrus-mediated pattern separation by regulating dendritic spine development
S Jain, SY Yoon, L Zhu, J Brodbeck, J Dai, D Walker, Y Huang
Public Library of Science 7 (9), e46340, 2012
472012
GlcNAc-Asn is a biomarker for NGLY1 deficiency
WF Mueller, L Zhu, B Tan, S Dwight, B Beahm, M Wilsey, T Wechsler, ...
J. Biochem. 171 (2), 177-186, 2022
152022
AAV9-NGLY1 gene replacement therapy improves phenotypic and biomarker endpoints in a rat model of NGLY1 deficiency
L Zhu, B Tan, SS Dwight, B Beahm, M Wilsey, BE Crawford, ...
Molecular Therapy-Methods & Clinical Development 27, 259-271, 2022
102022
“Slow” Voltage-Dependent Inactivation of CaV2. 2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA)
L Zhu, S McDavid, KPM Currie
PLoS One 10 (7), e0134117, 2015
82015
Life extension factor klotho enhances cognition. Cell Rep 7: 1065–1076
DB Dubal, JS Yokoyama, L Zhu, L Broestl, K Worden, D Wang, VE Sturm, ...
82014
Life extension factor klotho enhances cognition. Cell Rep. 2014; 7 (4): 1065–76
DB Dubal, JS Yokoyama, L Zhu, L Broestl, K Worden, D Wang
Epub 2014/05/13. doi: 10.1016/j. celrep. 2014.03. 076 PMID: 24813892 PubMed …, 0
7
Life extension factor klotho enhances cognition. Cell Rep 7 (4): 1065–1076
DB Dubal, JS Yokoyama, L Zhu, L Broestl, K Worden, D Wang, VE Sturm, ...
62014
Platform-agnostic thick-client system for combined delivery of disparate streaming content and dynamic content by combining dynamic data with output from a continuous queue …
J Specter, V Choudhary, L Zhu
US Patent 10,673,771, 2020
32020
Platform-agnostic thick-client system for combined delivery of disparate streaming content and dynamic content by combining dynamic data with output from a continuous queue …
J Specter, V Choudhary, L Zhu
US Patent 10,055,508, 2018
22018
P4‐287: Eliminating TAU in Human Neurons is Neuroprotective
C Wang, D Walker, L Zhu, Y Huang
Alzheimer's & Dementia 12, P1143-P1143, 2016
2016
Modulating Recovery of N-Type Calcium Channels from Voltage-Dependent Inactivation: A Novel PKC-Independent Effect of Phorbol Esters
L Zhu, SM McDavid, KPM Currie
Biophysical Journal 100 (3), 569a, 2011
2011
The neuron specific K-Cl cotransporter, KCC2, counteracts acute increases in intracellular Cl
L Zhu, E Delpire
FASEB JOURNAL 18 (4), A698-A698, 2004
2004
KCC2 plays a crucial role in cellular Cl-homeostasis in cultured neocortical neurons
L Zhu, E Delpire
FASEB JOURNAL 17 (4), A74-A74, 2003
2003
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