The fundamental role of epigenetic events in cancer PA Jones, SB Baylin Nature reviews genetics 3 (6), 415-428, 2002 | 7322 | 2002 |
Functions of DNA methylation: islands, start sites, gene bodies and beyond PA Jones Nature reviews genetics 13 (7), 484-492, 2012 | 6208 | 2012 |
The epigenomics of cancer PA Jones, SB Baylin Cell 128 (4), 683-692, 2007 | 5538 | 2007 |
Epigenetics in human disease and prospects for epigenetic therapy G Egger, G Liang, A Aparicio, PA Jones Nature 429 (6990), 457-463, 2004 | 4312 | 2004 |
Epigenetics in cancer S Sharma, TK Kelly, PA Jones Carcinogenesis 31 (1), 27-36, 2010 | 3368 | 2010 |
Cancer-epigenetics comes of age PA Jones, PW Laird Nature genetics 21 (2), 163-167, 1999 | 3325 | 1999 |
A decade of exploring the cancer epigenome—biological and translational implications SB Baylin, PA Jones Nature Reviews Cancer 11 (10), 726-734, 2011 | 3140 | 2011 |
The role of DNA methylation in mammalian epigenetics PA Jones, D Takai Science 293 (5532), 1068-1070, 2001 | 2628 | 2001 |
Cellular differentiation, cytidine analogs and DNA methylation PA Jones, SM Taylor Cell 20 (1), 85-93, 1980 | 2321 | 1980 |
Comprehensive analysis of CpG islands in human chromosomes 21 and 22 D Takai, PA Jones Proceedings of the national academy of sciences 99 (6), 3740-3745, 2002 | 2040 | 2002 |
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells Y Saito, G Liang, G Egger, JM Friedman, JC Chuang, GA Coetzee, ... Cancer cell 9 (6), 435-443, 2006 | 1734 | 2006 |
Epigenetic therapy of cancer: past, present and future CB Yoo, PA Jones Nature reviews Drug discovery 5 (1), 37-50, 2006 | 1683 | 2006 |
Multiple new phenotypes induced in 10T12 and 3T3 cells treated with 5-azacytidine SM Taylor, PA Jones Cell 17 (4), 771-779, 1979 | 1395 | 1979 |
Cancer genetics and epigenetics: two sides of the same coin? JS You, PA Jones Cancer cell 22 (1), 9-20, 2012 | 1356 | 2012 |
DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts D Roulois, HL Yau, R Singhania, Y Wang, A Danesh, SY Shen, H Han, ... Cell 162 (5), 961-973, 2015 | 1287 | 2015 |
Increased cell division as a cause of human cancer S Preston-Martin, MC Pike, RK Ross, PA Jones, BE Henderson Cancer research 50 (23), 7415-7421, 1990 | 1245 | 1990 |
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors KD Robertson, E Uzvolgyi, G Liang, C Talmadge, J Sumegi, FA Gonzales, ... Nucleic acids research 27 (11), 2291-2298, 1999 | 1187 | 1999 |
Epigenetic determinants of cancer SB Baylin, PA Jones Cold Spring Harbor perspectives in biology 8 (9), a019505, 2016 | 1157 | 2016 |
Targeting the cancer epigenome for therapy PA Jones, JPJ Issa, S Baylin Nature Reviews Genetics 17 (10), 630-641, 2016 | 1149 | 2016 |
Gene body methylation can alter gene expression and is a therapeutic target in cancer X Yang, H Han, DD De Carvalho, FD Lay, PA Jones, G Liang Cancer cell 26 (4), 577-590, 2014 | 1144 | 2014 |