The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator … CM Farinha, P Nogueira, F Mendes, D Penque, MD Amaral Biochemical Journal 366 (Pt 3), 797, 2002 | 166 | 2002 |
Metal-Based Inhibition of Poly (ADP-ribose) Polymerase− The Guardian Angel of DNA F Mendes, M Groessl, AA Nazarov, YO Tsybin, G Sava, I Santos, ... Journal of medicinal chemistry 54 (7), 2196-2206, 2011 | 164 | 2011 |
[(Cp‐R) M (CO) 3](M= Re or 99mTc) Arylsulfonamide, Arylsulfamide, and Arylsulfamate Conjugates for Selective Targeting of Human Carbonic Anhydrase IX D Can, B Spingler, P Schmutz, F Mendes, P Raposinho, C Fernandes, ... Angewandte Chemie International Edition 51 (14), 3354-3357, 2012 | 132 | 2012 |
Cystic fibrosis F508del patients have apically localized CFTR in a reduced number of airway cells D Penque, F Mendes, S Beck, C Farinha, P Pacheco, P Nogueira, ... Laboratory investigation 80 (6), 857-868, 2000 | 125 | 2000 |
Copper (II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity S Gama, F Mendes, F Marques, IC Santos, MF Carvalho, I Correia, ... Journal of inorganic biochemistry 105 (5), 637-644, 2011 | 102 | 2011 |
[RuII(η5-C5H5)(bipy)(PPh3)]+, a promising large spectrum antitumor agent: Cytotoxic activity and interaction with human serum albumin AI Tomaz, T Jakusch, TS Morais, F Marques, RFM De Almeida, F Mendes, ... Journal of inorganic biochemistry 117, 261-269, 2012 | 97 | 2012 |
S-nitrosoglutathione increases cystic fibrosis transmembrane regulator maturation K Zaman, M McPherson, J Vaughan, J Hunt, F Mendes, B Gaston, ... Biochemical and biophysical research communications 284 (1), 65-70, 2001 | 88 | 2001 |
Cytotoxic gold compounds: synthesis, biological characterization and investigation of their inhibition properties of the zinc finger protein PARP-1 M Serratrice, F Edafe, F Mendes, R Scopelliti, SM Zakeeruddin, M Grätzel, ... Dalton Transactions 41 (11), 3287-3293, 2012 | 85 | 2012 |
Copper (II) Complexes of Phenanthroline and Histidine Containing Ligands: Synthesis, Characterization and Evaluation of their DNA Cleavage and Cytotoxic Activity SMG Leite, LMP Lima, S Gama, F Mendes, M Orio, I Bento, A Paulo, ... Inorganic chemistry 55 (22), 11801-11814, 2016 | 76 | 2016 |
Evaluation of Acridine Orange Derivatives as DNA-Targeted Radiopharmaceuticals for Auger Therapy: Influence of the Radionuclide and Distance to DNA E Pereira, L Do Quental, E Palma, MC Oliveira, F Mendes, P Raposinho, ... Scientific reports 7, 42544, 2017 | 74 | 2017 |
Anticancer activity of structurally related ruthenium (II) cyclopentadienyl complexes L Côrte-Real, F Mendes, J Coimbra, TS Morais, AI Tomaz, A Valente, ... JBIC Journal of Biological Inorganic Chemistry 19 (6), 853-867, 2014 | 74 | 2014 |
Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator A Schmidt, LK Hughes, Z Cai, F Mendes, H Li, DN Sheppard, MD Amaral British journal of pharmacology 153 (6), 1311-1323, 2008 | 71 | 2008 |
Tricarbonyl M (I)(M= Re, 99mTc) complexes bearing acridine fluorophores: synthesis, characterization, DNA interaction studies and nuclear targeting T Esteves, C Xavier, S Gama, F Mendes, PD Raposinho, F Marques, ... Organic & biomolecular chemistry 8 (18), 4104-4116, 2010 | 56 | 2010 |
Deletion of CFTR translation start site reveals functional isoforms of the protein in CF patients AS Ramalho, MA Lewandowska, CM Farinha, F Mendes, J Gonçalves, ... Cellular Physiology and Biochemistry 24 (5-6), 335-346, 2009 | 54 | 2009 |
Anthracene-terpyridine metal complexes as new G-quadruplex DNA binders S Gama, I Rodrigues, F Mendes, IC Santos, E Gabano, B Klejevskaja, ... Journal of inorganic biochemistry 160, 275-286, 2016 | 53 | 2016 |
Evaluation of cellular uptake, cytotoxicity and cellular ultrastructural effects of heteroleptic oxidovanadium (IV) complexes of salicylaldimines and polypyridyl ligands G Scalese, I Correia, J Benítez, S Rostán, F Marques, F Mendes, ... Journal of inorganic biochemistry 166, 162-172, 2017 | 50 | 2017 |
Applicability of different antibodies for the immunohistochemical localization of CFTR in respiratory and intestinal tissues of human and murine origin L Doucet, F Mendes, T Montier, P Delépine, D Penque, C Férec, ... Journal of Histochemistry & Cytochemistry 51 (9), 1191-1199, 2003 | 45 | 2003 |
Antibodies for CFTR studies F Mendes, CM Farinha, M Roxo-Rosa, P Fanen, A Edelman, R Dormer, ... Journal of Cystic Fibrosis 3, 69-72, 2004 | 44 | 2004 |
Synthesis, characterization and biological evaluation of 99mTc/Re–tricarbonyl quinolone complexes TE Kydonaki, E Tsoukas, F Mendes, AG Hatzidimitriou, A Paulo, ... Journal of inorganic biochemistry 160, 94-105, 2016 | 41 | 2016 |
A comparison of 14 antibodies for the biochemical detection of the cystic fibrosis transmembrane conductance regulator protein CM Farinha, F Mendes, M Roxo-Rosa, D Penque, MD Amaral Molecular and cellular probes 18 (4), 235-242, 2004 | 40 | 2004 |