Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ... Natural product reports 30 (1), 108-160, 2013 | 2087 | 2013 |
Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin J Lubelski, R Rink, R Khusainov, GN Moll, OP Kuipers Cellular and molecular life sciences 65, 455-476, 2008 | 442 | 2008 |
Bacteriocins: mechanism of membrane insertion and pore formation GN Moll, WN Konings, AJM Driessen Antonie van Leeuwenhoek 76, 185-198, 1999 | 439 | 1999 |
Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis B Li, JPJ Yu, JS Brunzelle, GN Moll, WA Van Der Donk, SK Nair Science 311 (5766), 1464-1467, 2006 | 382 | 2006 |
Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin‐(1–7) or an angiotensin II receptor antagonist RM Wösten‐van Asperen, R Lutter, PA Specht, GN Moll, JB van Woensel, ... The Journal of pathology 225 (4), 618-627, 2011 | 357 | 2011 |
Angiotensin-(1-7) with thioether bridge: an angiotensin-converting enzyme-resistant, potent angiotensin-(1-7) analog LD Kluskens, SA Nelemans, R Rink, L de Vries, A Meter-Arkema, Y Wang, ... Journal of Pharmacology and Experimental Therapeutics 328 (3), 849-854, 2009 | 206 | 2009 |
NisT, the transporter of the lantibiotic nisin, can transport fully modified, dehydrated, and unmodified prenisin and fusions of the leader peptide with non-lantibiotic peptides A Kuipers, E de Boef, R Rink, S Fekken, LD Kluskens, AJM Driessen, ... Journal of biological chemistry 279 (21), 22176-22182, 2004 | 206 | 2004 |
Post-translational modification of therapeutic peptides by NisB, the dehydratase of the lantibiotic nisin LD Kluskens, A Kuipers, R Rink, E de Boef, S Fekken, AJM Driessen, ... Biochemistry 44 (38), 12827-12834, 2005 | 202 | 2005 |
Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation R Rink, J Wierenga, A Kuipers, LD Kluskens, AJM Driessen, OP Kuipers, ... Applied and environmental microbiology 73 (18), 5809-5816, 2007 | 191 | 2007 |
Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes R Rink, A Kuipers, E de Boef, KJ Leenhouts, AJM Driessen, GN Moll, ... Biochemistry 44 (24), 8873-8882, 2005 | 189 | 2005 |
To protect peptide pharmaceuticals against peptidases R Rink, A Arkema-Meter, I Baudoin, E Post, A Kuipers, SA Nelemans, ... Journal of pharmacological and toxicological methods 61 (2), 210-218, 2010 | 174 | 2010 |
Lactococcin G is a potassium ion-conducting, two-component bacteriocin G Moll, T Ubbink-Kok, H Hildeng-Hauge, J Nissen-Meyer, IF Nes, ... Journal of Bacteriology 178 (3), 600-605, 1996 | 155 | 1996 |
Complementary and overlapping selectivity of the two-peptide bacteriocins plantaricin EF and JK GN Moll, E van den Akker, HH Hauge, J Nissen-Meyer, IF Nes, ... Journal of Bacteriology 181 (16), 4848-4852, 1999 | 143 | 1999 |
Requirements of the engineered leader peptide of nisin for inducing modification, export, and cleavage A Plat, LD Kluskens, A Kuipers, R Rink, GN Moll Applied and environmental microbiology 77 (2), 604-611, 2011 | 119 | 2011 |
Role of transmembrane pH gradient and membrane binding in nisin pore formation GN Moll, J Clark, WC Chan, BW Bycroft, GC Roberts, WN Konings, ... Journal of bacteriology 179 (1), 135-140, 1997 | 116 | 1997 |
Mechanism of lantibiotic-induced pore-formation GN Moll, GCK Roberts, WN Konings, AJM Driessen Antonie van Leeuwenhoek 69, 185-191, 1996 | 114 | 1996 |
Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein JH Urban, MA Moosmeier, T Aumüller, M Thein, T Bosma, R Rink, K Groth, ... Nature Communications 8 (1), 1500, 2017 | 113 | 2017 |
Production of a Class II Two-Component Lantibiotic of Streptococcus pneumoniae Using the Class I Nisin Synthetic Machinery and Leader Sequence JA Majchrzykiewicz, J Lubelski, GN Moll, A Kuipers, JJE Bijlsma, ... Antimicrobial agents and chemotherapy 54 (4), 1498-1505, 2010 | 112 | 2010 |
NisC, the cyclase of the lantibiotic nisin, can catalyze cyclization of designed nonlantibiotic peptides R Rink, LD Kluskens, A Kuipers, AJM Driessen, OP Kuipers, GN Moll Biochemistry 46 (45), 13179-13189, 2007 | 112 | 2007 |
Plantaricin A is an amphiphilic α-helical bacteriocin-like pheromone which exerts antimicrobial and pheromone activities through different mechanisms HH Hauge, D Mantzilas, GN Moll, WN Konings, AJM Driessen, ... Biochemistry 37 (46), 16026-16032, 1998 | 107 | 1998 |