Functional normalization of 450k methylation array data improves replication in large cancer studies JP Fortin, A Labbe, M Lemire, BW Zanke, TJ Hudson, EJ Fertig, ... Genome biology 15 (11), 503, 2014 | 824 | 2014 |
sva: Surrogate variable analysis JT Leek, WE Johnson, HS Parker, EJ Fertig, AE Jaffe, JD Storey, Y Zhang, ... R package version 3 (0), 882-883, 2019 | 488 | 2019 |
p16 protein expression and human papillomavirus status as prognostic biomarkers of nonoropharyngeal head and neck squamous cell carcinoma CH Chung, Q Zhang, CS Kong, J Harris, EJ Fertig, PM Harari, D Wang, ... Journal of clinical oncology 32 (35), 3930-3938, 2014 | 416 | 2014 |
Single-cell RNA-seq analysis of retinal development identifies NFI factors as regulating mitotic exit and late-born cell specification BS Clark, GL Stein-O’Brien, F Shiau, GH Cannon, E Davis-Marcisak, ... Neuron 102 (6), 1111-1126. e5, 2019 | 352 | 2019 |
Activation of the NOTCH Pathway in Head and Neck Cancer W Sun, DA Gaykalova, MF Ochs, E Mambo, D Arnaoutakis, Y Liu, M Loyo, ... Cancer research 74 (4), 1091-1104, 2014 | 270 | 2014 |
Inferring causal molecular networks: empirical assessment through a community-based effort SM Hill, LM Heiser, T Cokelaer, M Unger, NK Nesser, DE Carlin, Y Zhang, ... Nature methods 13 (4), 310-318, 2016 | 244 | 2016 |
Enter the matrix: factorization uncovers knowledge from omics GL Stein-O’Brien, R Arora, AC Culhane, AV Favorov, LX Garmire, ... Trends in Genetics 34 (10), 790-805, 2018 | 223 | 2018 |
Single-cell analysis of human retina identifies evolutionarily conserved and species-specific mechanisms controlling development Y Lu, F Shiau, W Yi, S Lu, Q Wu, JD Pearson, A Kallman, S Zhong, ... Developmental cell 53 (4), 473-491. e9, 2020 | 198 | 2020 |
Programmed cell death ligand-1 (PD-L1) and CD8 expression profiling identify an immunologic subtype of pancreatic ductal adenocarcinomas with favorable survival L Danilova, WJ Ho, Q Zhu, T Vithayathil, A De Jesus-Acosta, NS Azad, ... Cancer immunology research 7 (6), 886-895, 2019 | 196 | 2019 |
Neoadjuvant cabozantinib and nivolumab convert locally advanced hepatocellular carcinoma into resectable disease with enhanced antitumor immunity WJ Ho, Q Zhu, J Durham, A Popovic, S Xavier, J Leatherman, A Mohan, ... Nature Cancer 2 (9), 891-903, 2021 | 192* | 2021 |
Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis E Lee, EJ Fertig, K Jin, S Sukumar, NB Pandey, AS Popel Nature communications 5 (1), 4715, 2014 | 186 | 2014 |
Key tumor suppressor genes inactivated by “greater promoter” methylation and somatic mutations in head and neck cancer R Guerrero-Preston, C Michailidi, L Marchionni, CR Pickering, ... Epigenetics 9 (7), 1031-1046, 2014 | 172 | 2014 |
A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy JS Di Martino, AR Nobre, C Mondal, I Taha, EF Farias, EJ Fertig, A Naba, ... Nature cancer 3 (1), 90-107, 2022 | 162 | 2022 |
A comparative study of 4D-VAR and a 4D ensemble Kalman filter: Perfect model simulations with Lorenz-96 EJ Fertig, J Harlim, BR Hunt Tellus A: Dynamic Meteorology and Oceanography 59 (1), 96-100, 2007 | 162 | 2007 |
Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA E Izumchenko, X Chang, M Brait, E Fertig, LT Kagohara, A Bedi, ... Nature communications 6 (1), 8258, 2015 | 154 | 2015 |
Decomposing cell identity for transfer learning across cellular measurements, platforms, tissues, and species GL Stein-O’Brien, BS Clark, T Sherman, C Zibetti, Q Hu, R Sealfon, S Liu, ... Cell systems 8 (5), 395-411. e8, 2019 | 140 | 2019 |
Aging-like spontaneous epigenetic silencing facilitates Wnt activation, stemness, and BrafV600E-induced tumorigenesis Y Tao, B Kang, DA Petkovich, YR Bhandari, J In, G Stein-O'Brien, X Kong, ... Cancer cell 35 (2), 315-328. e6, 2019 | 130 | 2019 |
Epigenetic regulation of gene expression in cancer: techniques, resources and analysis LT Kagohara, GL Stein-O’Brien, D Kelley, E Flam, HC Wick, LV Danilova, ... Briefings in functional genomics 17 (1), 49-63, 2018 | 122 | 2018 |
Preserving biological heterogeneity with a permuted surrogate variable analysis for genomics batch correction HS Parker, JT Leek, AV Favorov, M Considine, X Xia, S Chavan, ... Bioinformatics 30 (19), 2757-2763, 2014 | 116 | 2014 |
shinyMethyl: interactive quality control of Illumina 450k DNA methylation arrays in R JP Fortin, E Fertig, K Hansen F1000Research 3, 2014 | 109 | 2014 |