| Nuclear-import receptors reverse aberrant phase transitions of RNA-binding proteins with prion-like domains L Guo, HJ Kim, H Wang, J Monaghan, F Freyermuth, JC Sung, ... Cell 173 (3), 677-692. e20, 2018 | 430 | 2018 |
| Mechanism and regulation of cytoplasmic dynein MA Cianfrocco, ME DeSantis, AE Leschziner, SL Reck-Peterson Annual review of cell and developmental biology 31 (1), 83-108, 2015 | 251 | 2015 |
| Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events ME Jackrel, ME DeSantis, BA Martinez, LM Castellano, RM Stewart, ... Cell 156 (1), 170-182, 2014 | 247 | 2014 |
| Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients ME DeSantis, EH Leung, EA Sweeny, ME Jackrel, M Cushman-Nick, ... Cell 151 (4), 778-793, 2012 | 195 | 2012 |
| The human cytoplasmic dynein interactome reveals novel activators of motility WB Redwine, ME DeSantis, I Hollyer, ZM Htet, PT Tran, SK Swanson, ... Elife 6, e28257, 2017 | 136 | 2017 |
| Fission yeast does not age under favorable conditions, but does so after stress M Coelho, A Dereli, A Haese, S Kühn, L Malinovska, ME DeSantis, ... Current Biology 23 (19), 1844-1852, 2013 | 121 | 2013 |
| The Hsp104 N-terminal domain enables disaggregase plasticity and potentiation EA Sweeny, ME Jackrel, MS Go, MA Sochor, BM Razzo, ME DeSantis, ... Molecular cell 57 (5), 836-849, 2015 | 105 | 2015 |
| Lis1 has two opposing modes of regulating cytoplasmic dynein ME DeSantis, MA Cianfrocco, ZM Htet, PT Tran, SL Reck-Peterson, ... Cell 170 (6), 1197-1208. e12, 2017 | 91 | 2017 |
| The elusive middle domain of Hsp104 and ClpB: location and function ME DeSantis, J Shorter Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (1), 29-39, 2012 | 90 | 2012 |
| LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes ZM Htet, JP Gillies, RW Baker, AE Leschziner, ME DeSantis, ... Nature cell biology 22 (5), 518-525, 2020 | 89 | 2020 |
| Self-repair protects microtubules from destruction by molecular motors S Triclin, D Inoue, J Gaillard, ZM Htet, ME DeSantis, D Portran, E Derivery, ... Nature Materials 20 (6), 883-891, 2021 | 72 | 2021 |
| Hsp104 drives “protein-only” positive selection of Sup35 prion strains encoding strong [PSI+] ME DeSantis, J Shorter Chemistry & biology 19 (11), 1400-1410, 2012 | 56 | 2012 |
| Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation ME DeSantis, EA Sweeny, D Snead, EH Leung, MS Go, K Gupta, ... Journal of Biological Chemistry 289 (2), 848-867, 2014 | 54 | 2014 |
| Association energetics of cross-reactive and specific antibodies S Mohan, K Kourentzi, KA Schick, C Uehara, CA Lipschultz, M Acchione, ... Biochemistry 48 (6), 1390-1398, 2009 | 33 | 2009 |
| Purification of hsp104, a protein disaggregase EA Sweeny, ME DeSantis, J Shorter JoVE (Journal of Visualized Experiments), e3190, 2011 | 30 | 2011 |
| Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies M Acchione, CA Lipschultz, ME DeSantis, A Shanmuganathan, M Li, ... Molecular immunology 47 (2-3), 457-464, 2009 | 27 | 2009 |
| The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor R Agrawal, JP Gillies, JL Zang, J Zhang, SR Garrott, H Shibuya, ... Elife 11, e78201, 2022 | 18 | 2022 |
| Structures of human dynein in complex with the lissencephaly 1 protein, LIS1 JM Reimer, ME DeSantis, SL Reck-Peterson, AE Leschziner Elife 12, e84302, 2023 | 15 | 2023 |
| Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics M Acchione, YC Lee, ME DeSantis, CA Lipschultz, A Wlodawer, M Li, ... Biochemistry 51 (30), 6017-6027, 2012 | 14 | 2012 |
| Nde1 and Ndel1: outstanding mysteries in dynein-mediated transport SR Garrott, JP Gillies, ME DeSantis Frontiers in Cell and Developmental Biology 10, 871935, 2022 | 13 | 2022 |
