Manganese superoxide dismutase, MnSOD and its mimics S Miriyala, I Spasojevic, A Tovmasyan, D Salvemini, Z Vujaskovic, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (5), 794-814, 2012 | 438 | 2012 |
SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways I Batinic-Haberle, A Tovmasyan, ERH Roberts, Z Vujaskovic, KW Leong, ... Antioxidants & redox signaling 20 (15), 2372-2415, 2014 | 242 | 2014 |
An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins–from superoxide dismutation to H2O2-driven pathways I Batinic-Haberle, A Tovmasyan, I Spasojevic Redox biology 5, 43-65, 2015 | 161 | 2015 |
Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics I Batinic-Haberle, Z Rajic, A Tovmasyan, JS Reboucas, X Ye, KW Leong, ... Free Radical Biology and Medicine 51 (5), 1035-1053, 2011 | 156 | 2011 |
Mn porphyrin-based redox-active drugs: differential effects as cancer therapeutics and protectors of normal tissue against oxidative injury I Batinic-Haberle, A Tovmasyan, I Spasojevic Antioxidants & Redox Signaling 29 (16), 1691-1724, 2018 | 125 | 2018 |
Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities I Batinic-Haberle, I Spasojevic, HM Tse, A Tovmasyan, Z Rajic, ... Amino acids 42, 95-113, 2012 | 121 | 2012 |
Effect of molecular characteristics on cellular uptake, subcellular localization, and phototoxicity of Zn (II) N-alkylpyridylporphyrins R Ezzeddine, A Al-Banaw, A Tovmasyan, JD Craik, I Batinic-Haberle, ... Journal of Biological Chemistry 288 (51), 36579-36588, 2013 | 99 | 2013 |
Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators A Tovmasyan, H Sheng, T Weitner, A Arulpragasam, M Lu, DS Warner, ... Medical Principles and Practice 22 (2), 103-130, 2013 | 98 | 2013 |
A new SOD mimic, Mn (III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity Z Rajic, A Tovmasyan, I Spasojevic, H Sheng, M Lu, AM Li, EB Gralla, ... Free Radical Biology and Medicine 52 (9), 1828-1834, 2012 | 92 | 2012 |
A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics A Tovmasyan, CGC Maia, T Weitner, S Carballal, RS Sampaio, D Lieb, ... Free Radical Biology and Medicine 86, 308-321, 2015 | 91 | 2015 |
Novel manganese-porphyrin superoxide dismutase-mimetic widens the therapeutic margin in a preclinical head and neck cancer model KA Ashcraft, MK Boss, A Tovmasyan, KR Choudhury, AN Fontanella, ... International Journal of Radiation Oncology* Biology* Physics 93 (4), 892-900, 2015 | 82 | 2015 |
Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death MK Evans, A Tovmasyan, I Batinic-Haberle, GR Devi Free Radical Biology and Medicine 68, 302-314, 2014 | 82 | 2014 |
Anticancer therapeutic potential of Mn porphyrin/ascorbate system A Tovmasyan, RS Sampaio, MK Boss, JC Bueno-Janice, BH Bader, ... Free Radical Biology and Medicine 89, 1231-1247, 2015 | 75 | 2015 |
Radioprotection of the Brain White Matter by Mn(III) N-Butoxyethylpyridylporphyrin–Based Superoxide Dismutase Mimic MnTnBuOE-2-PyP5+ DH Weitzel, A Tovmasyan, KA Ashcraft, Z Rajic, T Weitner, C Liu, W Li, ... Molecular cancer therapeutics 14 (1), 70-79, 2015 | 75 | 2015 |
Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology A Tovmasyan, T Weitner, H Sheng, MM Lu, Z Rajic, DS Warner, ... Inorganic chemistry 52 (10), 5677-5691, 2013 | 74 | 2013 |
Simple biological systems for assessing the activity of superoxide dismutase mimics A Tovmasyan, JS Reboucas, L Benov Antioxidants & Redox Signaling 20 (15), 2416-2436, 2014 | 68 | 2014 |
Important cellular targets for antimicrobial photodynamic therapy MM Awad, A Tovmasyan, JD Craik, I Batinic-Haberle, LT Benov Applied microbiology and biotechnology 100, 7679-7688, 2016 | 64 | 2016 |
Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+ T Weitner, I Kos, H Sheng, A Tovmasyan, JS Reboucas, P Fan, ... Free Radical Biology and Medicine 58, 73-80, 2013 | 61 | 2013 |
Sublethal photodynamic treatment does not lead to development of resistance R Al-Mutairi, A Tovmasyan, I Batinic-Haberle, L Benov Frontiers in microbiology 9, 1699, 2018 | 58 | 2018 |
Cytotoxic effects of Mn (III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate X Ye, D Fels, A Tovmasyan, KM Aird, C Dedeugd, JL Allensworth, I Kos, ... Free radical research 45 (11-12), 1289-1306, 2011 | 58 | 2011 |