Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category D Luger, PB Silver, J Tang, D Cua, Z Chen, Y Iwakura, EP Bowman, ... The Journal of experimental medicine 205 (4), 799-810, 2008 | 810 | 2008 |
The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes MJ Mattapallil, EF Wawrousek, CC Chan, H Zhao, J Roychoudhury, ... Investigative ophthalmology & visual science 53 (6), 2921-2927, 2012 | 679 | 2012 |
A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens. RR Caspi, FG Roberge, CC Chan, B Wiggert, GJ Chader, LA Rozenszajn, ... Journal of immunology (Baltimore, Md.: 1950) 140 (5), 1490-1495, 1988 | 556 | 1988 |
Th1 and Th17 cells: adversaries and collaborators JM Damsker, AM Hansen, RR Caspi Annals of the New York Academy of Sciences 1183 (1), 211-221, 2010 | 550 | 2010 |
A look at autoimmunity and inflammation in the eye RR Caspi The Journal of clinical investigation 120 (9), 3073-3083, 2010 | 511 | 2010 |
Cutting edge: NKT cells constitutively express IL-23 receptor and RORγt and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion AV Rachitskaya, AM Hansen, R Horai, Z Li, R Villasmil, D Luger, ... The Journal of Immunology 180 (8), 5167-5171, 2008 | 500 | 2008 |
Calcitriol suppresses antiretinal autoimmunity through inhibitory effects on the Th17 effector response J Tang, RU Zhou, D Luger, W Zhu, PB Silver, RS Grajewski, SB Su, ... The Journal of Immunology 182 (8), 4624-4632, 2009 | 458 | 2009 |
T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat. RR Caspi, FG Roberge, CG McAllister, M El-Saied, T Kuwabara, I Gery, ... Journal of immunology (Baltimore, Md.: 1950) 136 (3), 928-933, 1986 | 435 | 1986 |
Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2–MyD88 signal pathway in dendritic cells and enhances Th2 immune responses D Yang, Q Chen, SB Su, P Zhang, K Kurosaka, RR Caspi, SM Michalek, ... The Journal of experimental medicine 205 (1), 79-90, 2008 | 420 | 2008 |
Microbiota-dependent activation of an autoreactive T cell receptor provokes autoimmunity in an immunologically privileged site R Horai, CR Zárate-Bladés, P Dillenburg-Pilla, J Chen, JL Kielczewski, ... Immunity 43 (2), 343-353, 2015 | 365 | 2015 |
Rodent models of experimental autoimmune uveitis RK Agarwal, PB Silver, RR Caspi Autoimmunity: Methods and Protocols, 443-469, 2012 | 346* | 2012 |
Inhibition of S-antigen induced experimental autoimmune uveoretinitis by oral induction of tolerance with S-antigen. RB Nussenblatt, RR Caspi, R Mahdi, CC Chan, F Roberge, O Lider, ... Journal of immunology (Baltimore, Md.: 1950) 144 (5), 1689-1695, 1990 | 338 | 1990 |
Spontaneous autoimmunity prevented by thymic expression of a single self-antigen J DeVoss, Y Hou, K Johannes, W Lu, GI Liou, J Rinn, H Chang, RR Caspi, ... The Journal of experimental medicine 203 (12), 2727-2735, 2006 | 328 | 2006 |
Experimental autoimmune uveoretinitis—rat and mouse RR Caspi Autoimmune Disease Models, 57-81, 1994 | 295 | 1994 |
Ocular immune privilege R Zhou, RR Caspi F1000 biology reports 2, 2010 | 275 | 2010 |
An ocular commensal protects against corneal infection by driving an interleukin-17 response from mucosal γδ T cells AJS Leger, JV Desai, RA Drummond, A Kugadas, F Almaghrabi, P Silver, ... Immunity 47 (1), 148-158. e5, 2017 | 262 | 2017 |
Interleukin 12 protects from a T helper type 1–mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon γ, nitric oxide, and apoptosis TK Tarrant, PB Silver, JL Wahlsten, LV Rizzo, CC Chan, B Wiggert, ... The Journal of experimental medicine 189 (2), 219-230, 1999 | 248 | 1999 |
IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response. LS Jones, LV Rizzo, RK Agarwal, TK Tarrant, CC Chan, B Wiggert, ... Journal of immunology (Baltimore, Md.: 1950) 158 (12), 5997-6005, 1997 | 237 | 1997 |
A new immunomodulating compound (AS-101) with potential therapeutic application B Sredni, RR Caspi, A Klein, Y Kalechman, Y Danziger, M Benya'Akov, ... Nature 330 (6144), 173-176, 1987 | 221 | 1987 |
Pathology of experimental autoimmune uveoretinitis in mice CC Chan, RR Caspi, M Ni, WC Leake, B Wiggert, GJ Chader, ... Journal of autoimmunity 3 (3), 247-255, 1990 | 216 | 1990 |