Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface AJ Farrand, S LaChapelle, EM Hotze, AE Johnson, RK Tweten Proceedings of the National Academy of Sciences 107 (9), 4341-4346, 2010 | 235 | 2010 |
MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese TE Kehl-Fie, Y Zhang, JL Moore, AJ Farrand, MI Hood, S Rathi, ... Infection and immunity 81 (9), 3395-3405, 2013 | 207 | 2013 |
Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation SL Lawrence, SC Feil, CJ Morton, AJ Farrand, TD Mulhern, MA Gorman, ... Scientific reports 5 (1), 1-13, 2015 | 85 | 2015 |
Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8α and C9 SE Wickham, EM Hotze, AJ Farrand, G Polekhina, TL Nero, S Tomlinson, ... Journal of Biological Chemistry 286 (23), 20952-20962, 2011 | 71 | 2011 |
Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins EM Hotze, E Wilson-Kubalek, AJ Farrand, L Bentsen, MW Parker, ... Journal of Biological Chemistry 287 (29), 24534-24543, 2012 | 61 | 2012 |
Current perspectives on biosimilars FK Agbogbo, DM Ecker, A Farrand, K Han, A Khoury, A Martin, J McCool, ... Journal of Industrial Microbiology and Biotechnology 46 (9-10), 1297-1311, 2019 | 60 | 2019 |
Regulation of host hemoglobin binding by the Staphylococcus aureus Clp proteolytic system AJ Farrand, ML Reniere, H Ingmer, D Frees, EP Skaar Journal of bacteriology 195 (22), 5041-5050, 2013 | 59 | 2013 |
The cholesterol-dependent cytolysin membrane-binding interface discriminates lipid environments of cholesterol to support β-barrel pore insertion AJ Farrand, EM Hotze, TK Sato, KR Wade, WC Wimley, AE Johnson, ... Journal of Biological Chemistry 290 (29), 17733-17744, 2015 | 53 | 2015 |
Toward improving therapeutic regimens for Bacillus endophthalmitis BJ Wiskur, ML Robinson, AJ Farrand, BD Novosad, MC Callegan Investigative ophthalmology & visual science 49 (4), 1480-1487, 2008 | 43 | 2008 |
An iron-regulated autolysin remodels the cell wall to facilitate heme acquisition in Staphylococcus lugdunensis AJ Farrand, KP Haley, NM Lareau, S Heilbronner, JA McLean, T Foster, ... Infection and immunity 83 (9), 3578-3589, 2015 | 23 | 2015 |
Molecular basis for the evolution of species-specific hemoglobin capture by Staphylococcus aureus JE Choby, HB Buechi, AJ Farrand, EP Skaar, MF Barber MBio 9 (6), 2018 | 18 | 2018 |
Proteomic analyses of iron-responsive, Clp-dependent changes in Staphylococcus aureus AJ Farrand, DB Friedman, ML Reniere, H Ingmer, D Frees, EP Skaar Pathogens and disease 73 (3), ftv004, 2015 | 16 | 2015 |
Chlamydomonas reinhardtii LFO1 is an IsdG family heme oxygenase LJ Lojek, AJ Farrand, JH Wisecaver, CE Blaby-Haas, BW Michel, ... Msphere 2 (4), 2017 | 15 | 2017 |
The structural basis for a transition state that regulates pore formation in a bacterial toxin KR Wade, SL Lawrence, AJ Farrand, EM Hotze, MJ Kuiper, MA Gorman, ... Mbio 10 (2), 2019 | 13 | 2019 |
Fur regulation of Staphylococcus aureus heme oxygenases is required for heme homeostasis LJ Lojek, AJ Farrand, A Weiss, EP Skaar International Journal of Medical Microbiology 308 (6), 582-589, 2018 | 12 | 2018 |
Heme and infectious diseases AJ Farrand, EP Skaar Handbook of Porphyrin Science (Volume 26) With Applications to Chemistry …, 2014 | 10 | 2014 |
Molecular basis for the evolution of species-specific hemoglobin capture by pathogenic Staphylococcus JE Choby, HB Buechi, AJ Farrand, EP Skaar, MF Barber bioRxiv, 339705, 2018 | 1 | 2018 |
Chlamydomonas reinhardtii LFO1 is an IsdG family heme oxygenase. mSphere 2: e00176-17 LJ Lojek, AJ Farrand, JH Wisecaver, CE Blaby-Haas, BW Michel, ... | 1 | 2017 |
Regulation of Virulence by Iron in Gram‐Positive Bacteria AJ Farrand, EP Skaar Regulation of Bacterial Virulence, 79-105, 2012 | | 2012 |
Characterization of the membrane recognition mechanism of the cholesterol-dependent cytolysins AJ Farrand The University of Oklahoma Health Sciences Center, 2010 | | 2010 |