Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy C Kadoch, DC Hargreaves, C Hodges, L Elias, L Ho, J Ranish, ... Nature genetics 45 (6), 592-601, 2013 | 1393 | 2013 |
Chromatin remodelling during development L Ho, GR Crabtree Nature 463 (7280), 474-484, 2010 | 1311 | 2010 |
Comprehensive methylome map of lineage commitment from haematopoietic progenitors H Ji, LIR Ehrlich, J Seita, P Murakami, A Doi, P Lindau, H Lee, MJ Aryee, ... Nature 467 (7313), 338-342, 2010 | 748 | 2010 |
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency L Ho, JL Ronan, J Wu, BT Staahl, L Chen, A Kuo, J Lessard, ... Proceedings of the National Academy of Sciences 106 (13), 5181-5186, 2009 | 658 | 2009 |
ELABELA: a hormone essential for heart development signals via the apelin receptor SC Chng, L Ho, J Tian, B Reversade Developmental cell 27 (6), 672-680, 2013 | 508 | 2013 |
An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network L Ho, R Jothi, JL Ronan, K Cui, K Zhao, GR Crabtree Proceedings of the National Academy of Sciences 106 (13), 5187-5191, 2009 | 490 | 2009 |
esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function L Ho, EL Miller, JL Ronan, WQ Ho, R Jothi, GR Crabtree Nature cell biology 13 (8), 903-913, 2011 | 303 | 2011 |
ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice L Ho, M Van Dijk, STJ Chye, DM Messerschmidt, SC Chng, S Ong, LK Yi, ... Science 357 (6352), 707-713, 2017 | 226 | 2017 |
ELABELA is an endogenous growth factor that sustains hESC self-renewal via the PI3K/AKT pathway L Ho, SYX Tan, S Wee, Y Wu, SJC Tan, NB Ramakrishna, SC Chng, ... Cell stem cell 17 (4), 435-447, 2015 | 183 | 2015 |
ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage T Sato, C Sato, A Kadowaki, H Watanabe, L Ho, J Ishida, T Yamaguchi, ... Cardiovascular research 113 (7), 760-769, 2017 | 144 | 2017 |
Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance M Buscarlet, V Krasteva, L Ho, C Simon, J Hébert, B Wilhelm, ... Blood, The Journal of the American Society of Hematology 123 (11), 1720-1728, 2014 | 120 | 2014 |
Brg1 modulates enhancer activation in mesoderm lineage commitment JM Alexander, SK Hota, D He, S Thomas, L Ho, LA Pennacchio, ... Development 142 (8), 1418-1430, 2015 | 116 | 2015 |
Alternative progenitor cells compensate to rebuild the coronary vasculature in Elabela-and Apj-deficient hearts B Sharma, L Ho, GH Ford, HI Chen, AB Goldstone, YJ Woo, ... Developmental Cell 42 (6), 655-666. e3, 2017 | 105 | 2017 |
Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly S Zhang, B Reljić, C Liang, B Kerouanton, JC Francisco, JH Peh, C Mary, ... Nature communications 11 (1), 1312, 2020 | 99 | 2020 |
C5orf42 is the major gene responsible for OFD syndrome type VI E Lopez, C Thauvin-Robinet, B Reversade, NE Khartoufi, L Devisme, ... Human genetics 133, 367-377, 2014 | 88 | 2014 |
Calcineurin sets the bandwidth for discrimination of signals during thymocyte development EM Gallo, MM Winslow, K Canté-Barrett, AN Radermacher, L Ho, ... Nature 450 (7170), 731-735, 2007 | 79 | 2007 |
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome KS Robinson, GA Toh, P Rozario, R Chua, S Bauernfried, Z Sun, ... Science 377 (6603), 328-335, 2022 | 70 | 2022 |
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity CQE Lee, B Kerouanton, S Chothani, S Zhang, Y Chen, CK Mantri, ... Nature communications 12 (1), 2130, 2021 | 69 | 2021 |
A high-resolution map of human RNA translation SP Chothani, E Adami, AA Widjaja, SR Langley, S Viswanathan, CJ Pua, ... Molecular cell 82 (15), 2885-2899. e8, 2022 | 51 | 2022 |
Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage M He, ACY Kuk, M Ding, CF Chin, DLA Galam, JM Nah, BC Tan, HL Yeo, ... Proceedings of the National Academy of Sciences 119 (40), e2210353119, 2022 | 35 | 2022 |