Mechanistic studies of a calcium-dependent MRI contrast agent W Li, G Parigi, M Fragai, C Luchinat, TJ Meade Inorganic Chemistry 41 (15), 4018-4024, 2002 | 233 | 2002 |
Conformational variability of matrix metalloproteinases: beyond a single 3D structure I Bertini, V Calderone, M Cosenza, M Fragai, YM Lee, C Luchinat, ... Proceedings of the National Academy of Sciences 102 (15), 5334-5339, 2005 | 172 | 2005 |
The G‐Triplex DNA V Limongelli, S De Tito, L Cerofolini, M Fragai, B Pagano, R Trotta, ... Angewandte Chemie International Edition 52 (8), 2269-2273, 2013 | 165 | 2013 |
Structural basis for matrix metalloproteinase 1-catalyzed collagenolysis I Bertini, M Fragai, C Luchinat, M Melikian, M Toccafondi, JL Lauer, ... Journal of the American Chemical Society 134 (4), 2100-2110, 2012 | 128 | 2012 |
Snapshots of the reaction mechanism of matrix metalloproteinases I Bertini, V Calderone, M Fragai, C Luchinat, M Maletta, KJ Yeo Angewandte Chemie International Edition 45 (47), 7952-7955, 2006 | 126 | 2006 |
NMR-based techniques in the hit identification and optimisation processes M Pellecchia, B Becattini, KJ Crowell, R Fattorusso, M Forino, M Fragai, ... Expert opinion on therapeutic targets 8 (6), 597-611, 2004 | 100 | 2004 |
Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12 I Bertini, V Calderone, M Fragai, R Jaiswal, C Luchinat, M Melikian, ... Journal of the American Chemical Society 130 (22), 7011-7021, 2008 | 90 | 2008 |
Entropic contribution to the linking coefficient in fragment based drug design: a case study V Borsi, V Calderone, M Fragai, C Luchinat, N Sarti Journal of Medicinal Chemistry 53 (10), 4285-4289, 2010 | 87 | 2010 |
Exploring the subtleties of drug− receptor interactions: the case of matrix metalloproteinases I Bertini, V Calderone, M Fragai, A Giachetti, M Loconte, C Luchinat, ... Journal of the American Chemical Society 129 (9), 2466-2475, 2007 | 86 | 2007 |
G-triplex structure and formation propensity L Cerofolini, J Amato, A Giachetti, V Limongelli, E Novellino, M Parrinello, ... Nucleic acids research 42 (21), 13393-13404, 2014 | 84 | 2014 |
Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin I Bertini, V Calderone, M Fragai, C Luchinat, E Talluri Journal of medicinal chemistry 52 (15), 4838-4843, 2009 | 82 | 2009 |
Interdomain flexibility in full-length matrix metalloproteinase-1 (MMP-1) I Bertini, M Fragai, C Luchinat, M Melikian, E Mylonas, N Sarti, DI Svergun Journal of Biological Chemistry 284 (19), 12821-12828, 2009 | 79 | 2009 |
Regulation of HuR structure and function by dihydrotanshinone-I P Lal, L Cerofolini, VG D’Agostino, C Zucal, C Fuccio, I Bonomo, E Dassi, ... Nucleic acids research 45 (16), 9514-9527, 2017 | 77 | 2017 |
Sulfonamide‐Functionalized Gadolinium DTPA Complexes as Possible Contrast Agents for MRI: A Relaxometric Investigation PL Anelli, I Bertini, M Fragai, L Lattuada, C Luchinat, G Parigi European Journal of Inorganic Chemistry 2000 (4), 625-630, 2000 | 76 | 2000 |
1H NMRD profiles of diamagnetic proteins: a model‐free analysis† I Bertini, M Fragai, C Luchinat, G Parigi Magnetic Resonance in Chemistry 38 (7), 543-550, 2000 | 74 | 2000 |
Examination of matrix metalloproteinase-1 in solution: a preference for the pre-collagenolysis state L Cerofolini, GB Fields, M Fragai, CFGC Geraldes, C Luchinat, G Parigi, ... Journal of Biological Chemistry 288 (42), 30659-30671, 2013 | 72 | 2013 |
Persistent contrast enhancement by sterically stabilized paramagnetic liposomes in murine melanoma I Bertini, F Bianchini, L Calorini, S Colagrande, M Fragai, A Franchi, ... Magnetic resonance in medicine 52 (3), 669-672, 2004 | 68 | 2004 |
Paramagnetic metal ions in ligand screening: The CoII matrix metalloproteinase 12 I Bertini, M Fragai, YM Lee, C Luchinat, B Terni Angewandte Chemie International Edition 43 (17), 2254-2256, 2004 | 66 | 2004 |
A calix [4] arene GdIII complex endowed with high stability, relaxivity, and binding affinity to serum albumin S Aime, A Barge, M Botta, A Casnati, M Fragai, C Luchinat, R Ungaro Angewandte Chemie International Edition 40 (24), 4737-4739, 2001 | 64 | 2001 |
Unraveling hidden regulatory sites in structurally homologous metalloproteases Y Udi, M Fragai, M Grossman, S Mitternacht, R Arad-Yellin, V Calderone, ... Journal of molecular biology 425 (13), 2330-2346, 2013 | 63 | 2013 |