Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A KM White, R Rosales, S Yildiz, T Kehrer, L Miorin, E Moreno, S Jangra, ... Science 371 (6532), 926-931, 2021 | 303 | 2021 |
Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs J Kouznetsova, W Sun, C Martínez-Romero, G Tawa, P Shinn, CZ Chen, ... Emerging microbes & infections 3 (1), 1-7, 2014 | 262 | 2014 |
Virus-induced senescence is a driver and therapeutic target in COVID-19 S Lee, Y Yu, J Trimpert, F Benthani, M Mairhofer, P Richter-Pechanska, ... Nature 599 (7884), 283-289, 2021 | 241 | 2021 |
The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon M Laurent-Rolle, J Morrison, R Rajsbaum, JML Macleod, G Pisanelli, ... Cell host & microbe 16 (3), 314-327, 2014 | 173 | 2014 |
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response R Rajsbaum, GA Versteeg, S Schmid, AM Maestre, A Belicha-Villanueva, ... Immunity 40 (6), 880-895, 2014 | 158 | 2014 |
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry S Yang, M Xu, EM Lee, K Gorshkov, SA Shiryaev, S He, W Sun, ... Cell discovery 4 (1), 31, 2018 | 151 | 2018 |
The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera R Rathnasinghe, S Jangra, A Cupic, C Martínez-Romero, LCF Mulder, ... MedRxiv, 2021 | 111 | 2021 |
Synergistic drug combination effectively blocks Ebola virus infection W Sun, S He, C Martínez-Romero, J Kouznetsova, G Tawa, M Xu, P Shinn, ... Antiviral research 137, 165-172, 2017 | 102 | 2017 |
N-glycolylneuraminic acid as a receptor for influenza A viruses F Broszeit, N Tzarum, X Zhu, N Nemanichvili, D Eggink, T Leenders, Z Li, ... Cell reports 27 (11), 3284-3294. e6, 2019 | 94 | 2019 |
Innate immune response to influenza virus at single-cell resolution in human epithelial cells revealed paracrine induction of interferon lambda 1 I Ramos, G Smith, F Ruf-Zamojski, C Martínez-Romero, M Fribourg, ... Journal of virology 93 (20), 10.1128/jvi. 00559-19, 2019 | 85 | 2019 |
Antiviral role of IFITM proteins in African swine fever virus infection R Muñoz-Moreno, MÁ Cuesta-Geijo, C Martínez-Romero, L Barrado-Gil, ... PloS one 11 (4), e0154366, 2016 | 73 | 2016 |
The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma C Martínez‐Romero, I Rooman, A Skoudy, C Guerra, X Molero, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009 | 66 | 2009 |
Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions RP de Vries, E de Vries, C Martínez-Romero, R McBride, ... Journal of virology 87 (24), 13868-13877, 2013 | 48 | 2013 |
Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death BM Hartmann, RA Albrecht, E Zaslavsky, G Nudelman, H Pincas, ... Nature communications 8 (1), 1931, 2017 | 47 | 2017 |
Hybrid gene origination creates human-virus chimeric proteins during infection JSY Ho, M Angel, Y Ma, E Sloan, G Wang, C Martinez-Romero, ... Cell 181 (7), 1502-1517. e23, 2020 | 39 | 2020 |
The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells A Bosch, K Panoutsopoulou, JM Corominas, R Gimeno, G Moreno-Bueno, ... Oncotarget 5 (8), 2065, 2014 | 39 | 2014 |
ISG15 is counteracted by vaccinia virus E3 protein and controls the proinflammatory response against viral infection B Eduardo-Correia, C Martínez-Romero, A García-Sastre, S Guerra Journal of virology 88 (4), 2312-2318, 2014 | 39 | 2014 |
Computer-aided discovery and characterization of novel Ebola virus inhibitors SJ Capuzzi, W Sun, EN Muratov, C Martínez-Romero, S He, W Zhu, H Li, ... Journal of medicinal chemistry 61 (8), 3582-3594, 2018 | 38 | 2018 |
Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera R Rathnasinghe, S Jangra, C Ye, A Cupic, G Singh, C Martínez-Romero, ... Nature Communications 13 (1), 3921, 2022 | 25 | 2022 |
Modeling SARS-CoV-2: comparative pathology in rhesus macaque and Golden Syrian hamster models S Choudhary, I Kanevsky, S Yildiz, RS Sellers, KA Swanson, T Franks, ... Toxicologic pathology 50 (3), 280-293, 2022 | 23 | 2022 |