Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms J Liu, JE Burdette, H Xu, C Gu, RB Van Breemen, KPL Bhat, N Booth, ... Journal of agricultural and food chemistry 49 (5), 2472-2479, 2001 | 663 | 2001 |
Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships A Constantinou, R Mehta, C Runyan, K Rao, A Vaughan, R Moon Journal of natural products 58 (2), 217-225, 1995 | 362 | 1995 |
Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein A Constantinou, K Kiguchi, E Huberman Cancer Research 50 (9), 2618-2624, 1990 | 347 | 1990 |
Vitamin E and cancer: An insight into the anticancer activities of vitamin E isomers and analogs C Constantinou, A Papas, AI Constantinou International journal of cancer 123 (4), 739-752, 2008 | 342 | 2008 |
Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage RG Mehta, J Liu, A Constantinou, CF Thomas, M Hawthorne, M You, ... Carcinogenesis 16 (2), 399-404, 1995 | 287 | 1995 |
Genistein as an inducer of tumor cell differentiation: possible mechanisms of action A Constantinou, E Huberman Proceedings of the Society for Experimental Biology and Medicine 208 (1 …, 1995 | 258 | 1995 |
Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer V Punj, S Bhattacharyya, D Saint-Dic, C Vasu, EA Cunningham, J Graves, ... Oncogene 23 (13), 2367-2378, 2004 | 210 | 2004 |
Genistein induces maturation of cultured human breast cancer cells and prevents tumor growth in nude mice AI Constantinou, EK Aron, RM Rajeshwari The American journal of clinical nutrition 68 (6), 1426S-1430S, 1998 | 178 | 1998 |
Genistein inactivates bcl-2, delays the G2/M phase of the cell cycle, and induces apoptosis of human breast adenocarcinoma MCF-7 cells AI Constantinou, N Kamath, JS Murley European Journal of Cancer 34 (12), 1927-1934, 1998 | 167 | 1998 |
Genistein induces apoptosis and topoisomerase II-mediated DNA breakage in colon cancer cells GI Salti, S Grewal, RR Mehta, TKD Gupta, AW Boddie Jr, AI Constantinou European Journal of Cancer 36 (6), 796-802, 2000 | 166 | 2000 |
Inhibition of N-methyl-N-nitrosourea-induced mammary tumors in rats by the soybean isoflavones. AI Constantinou, RG Mehta, A Vaughan Anticancer Research 16 (6A), 3293-3298, 1996 | 164 | 1996 |
Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarboxylase C Gerhäuser, W Mar, SK Lee, N Suh, Y Luo, J Kosmeder, L Luyengi, ... Nature Medicine 1 (3), 260-266, 1995 | 161 | 1995 |
Chemopreventive effects of soy protein and purified soy isoflavones on DMBA-induced mammary tumors in female Sprague-Dawley rats AI Constantinou, D Lantvit, M Hawthorne, X Xu, RB van Breemen, ... Nutrition and cancer 41 (1-2), 75-81, 2001 | 136 | 2001 |
D-alpha-tocopheryl polyethylene glycol succinate (TPGS) induces cell cycle arrest and apoptosis selectively in Survivin-overexpressing breast cancer cells CM Neophytou, C Constantinou, P Papageorgis, AI Constantinou Biochemical pharmacology 89 (1), 31-42, 2014 | 133 | 2014 |
Dietary soy isoflavones and estrone protect ovariectomized ERαKO and wild-type mice from carcinogen-induced colon cancer JY Guo, X Li, JD Browning Jr, RS MacDonald, GE Rottinghaus, ... The Journal of nutrition 134 (1), 179-182, 2004 | 132 | 2004 |
Black Cohosh (Cimicifuga racemosa L.) Protects against Menadione-Induced DNA Damage through Scavenging of Reactive Oxygen Species: Bioassay-Directed … JE Burdette, S Chen, ZZ Lu, H Xu, BEP White, DS Fabricant, J Liu, ... Journal of Agricultural and Food Chemistry 50 (24), 7022-7028, 2002 | 130 | 2002 |
Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized Sprague-Dawley rats JE Burdette, J Liu, D Lantvit, E Lim, N Booth, KPL Bhat, S Hedayat, ... The Journal of nutrition 132 (1), 27-30, 2002 | 128 | 2002 |
Prevention of Preneoplastic Mammary Lesion Development by a Novel Vitamin D Analogue, 1α-Hydroxyvitamin D 5 RG Mehta, RR Mehta, G Lazzaro, A Constantinou, RM Moriarty, ... Journal of the National Cancer Institute 89 (3), 212-218, 1997 | 125 | 1997 |
The phosphoform of the regulatory subunit RII of cyclic AMP-dependent protein kinase possesses intrinsic topoisomerase activity AI Constantinou, SP Squinto, RA Jungmann Cell 42 (2), 429-437, 1985 | 124 | 1985 |
Caspase-independent pathways of programmed cell death: the unraveling of new targets of cancer therapy? C Constantinou, KA Papas, AI Constantinou Current cancer drug targets 9 (6), 717-728, 2009 | 121 | 2009 |