| Cryo–electron microscopy structure and analysis of the P-Rex1–Gβγ signaling scaffold JN Cash, S Urata, S Li, SK Ravala, LV Avramova, MD Shost, JS Gutkind, ... Science advances 5 (10), eaax8855, 2019 | 34 | 2019 |
| Evidence that phosphorylation of threonine in the GT motif triggers activation of PknA, a eukaryotic‐type serine/threonine kinase from Mycobacterium tuberculosis SK Ravala, S Singh, GS Yadav, S Kumar, S Karthikeyan, PK Chakraborti The FEBS journal 282 (8), 1419-1431, 2015 | 22 | 2015 |
| The first DEP domain of the RhoGEF P-Rex1 autoinhibits activity and contributes to membrane binding SK Ravala, JB Hopkins, CB Plescia, SR Allgood, MA Kane, JN Cash, ... Journal of Biological Chemistry 295 (36), 12635-12647, 2020 | 15 | 2020 |
| Phosphorylation modulates catalytic activity of mycobacterial sirtuins GS Yadav, SK Ravala, N Malhotra, PK Chakraborti Frontiers in microbiology 7, 677, 2016 | 8 | 2016 |
| Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1 SJ Bandekar, CL Chen, SK Ravala, JN Cash, LV Avramova, MV Zhalnina, ... Journal of Biological Chemistry 298 (8), 2022 | 5 | 2022 |
| New mechanisms underlying oncogenesis in Dbl family Rho guanine nucleotide exchange factors SK Ravala, JJG Tesmer Molecular Pharmacology 106 (3), 117-128, 2024 | 1 | 2024 |
| Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4 SK Ravala, SR Adame-Garcia, S Li, CL Chen, MA Cianfrocco, JS Gutkind, ... Elife 12, RP92822, 2024 | 1 | 2024 |
| Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ CL Chen, R Syahirah, SK Ravala, YC Yen, T Klose, Q Deng, JJG Tesmer Nature Structural & Molecular Biology, 1-10, 2024 | 1 | 2024 |
| Structural Dynamics in RhoGEF Signaling Investigated Using Model Cell Membranes J Cash, S Ravala, SR Adame-Garcia, S Li, CL Chen, M Cianfrocco, ... Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024 | | 2024 |
| Structural dynamics in RhoGEF signaling investigated using model cell membranes S Ravala, S Adame-Garcia, S Li, CL Chen, MA Cianfrocco, JS Gutkind, ... Biophysical Journal 123 (3), 152a, 2024 | | 2024 |
| Mechanistic and Structural Studies of the Membrane-associated RhoGEF P-Rex and its Modes of Regulation L Anderson, S Ravala, S Li, J Tesmer, J Cash PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
| Structural and Mechanistic Basis for Gbetagamma-mediated Activation of Phosphoinositide 3-kinase-gamma CL Chen, S Ravala, YC Yen, T Klose, R Syahirah, JJG Tesmer, Q Deng Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
| New insights into regulation of P‐Rex1 autoinhibition SK Ravala, S Li, CL Chen, MA Cianfrocco, JN Cash, JJG Tesmer The FASEB Journal 36, 2022 | | 2022 |
| Single Particle Cryo‐EM Reconstruction of the P‐Rex1–Gβγ Complex Reveals Mechanisms Underlying Cellular Migration Mediated by GPCRs J Cash, S Urata, S Li, S Ravala, M Cianfrocco, J Tesmer The FASEB Journal 33 (S1), 668.2-668.2, 2019 | | 2019 |
| Structural Snapshots of a Dynamic Process in the Regulation of P-Rex, a Metastatic Factor JN Cash, S Ravala, JJG Tesmer, MA Cianfrocco Microscopy and Microanalysis 24 (S1), 1218-1219, 2018 | | 2018 |
| Structural Characterization of the DEP Domains of P-Rex1 SR Allgood, JJG Tesmer, SK Ravala | | 2018 |
| Evidence for the interplay between post‐translational modifications in regulating mycobacterial sirtuin activity GS Yadav, SK Ravala, N Malhotra, PK Chakraborti The FASEB Journal 30, 1131.1-1131.1, 2016 | | 2016 |
| Deciphering crucial threonines towards functionality of an essential eukaryotic‐type Ser/Thr kinase from M. tuberculosis (802.1) S Ravala, G Yadav, P Chakraborti The FASEB Journal 28, 802.1, 2014 | | 2014 |
| Studies on a mycobacterial eukaryotic-type serine/theronine kinase and its interacting partners SK Ravala CSIR-IMTECH, Chandigarh/Jawaharlal Nehru University, New Delhi, 2013 | | 2013 |
| Eukaryotic-type Serine/Threonine kinase mediated phosphorylation at Threonine-169 perturbs mycobacterial guanylate kinase activity GS Yadav, SK Ravala, S Kachhap, M Thakur, A Roy, B Singh, ... | | |
