Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1850* | 2020 |
New brain tumor entities emerge from molecular classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 858 | 2016 |
Accurate and efficient detection of gene fusions from RNA sequencing data S Uhrig, J Ellermann, T Walther, P Burkhardt, M Fröhlich, B Hutter, ... Genome research 31 (3), 448-460, 2021 | 295 | 2021 |
NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer C Heining, P Horak, S Uhrig, PL Codo, B Klink, B Hutter, M Fröhlich, ... Cancer discovery 8 (9), 1087-1095, 2018 | 228 | 2018 |
Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations J Jabs, FM Zickgraf, J Park, S Wagner, X Jiang, K Jechow, K Kleinheinz, ... Molecular systems biology 13 (11), 955, 2017 | 212 | 2017 |
Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma S Jansky, AK Sharma, V Körber, A Quintero, UH Toprak, EM Wecht, ... Nature genetics 53 (5), 683-693, 2021 | 186 | 2021 |
Conserved peptide fragmentation as a benchmarking tool for mass spectrometers and a discriminating feature for targeted proteomics UH Toprak, LC Gillet, A Maiolica, P Navarro, A Leitner, R Aebersold Molecular & Cellular Proteomics 13 (8), 2056-2071, 2014 | 129 | 2014 |
Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma C López, K Kleinheinz, SM Aukema, M Rohde, SH Bernhart, ... Nature communications 10 (1), 1459, 2019 | 124 | 2019 |
Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer N Ishaque, ML Abba, C Hauser, N Patil, N Paramasivam, ... Nature communications 9 (1), 4782, 2018 | 121 | 2018 |
Super enhancers define regulatory subtypes and cell identity in neuroblastoma M Gartlgruber, AK Sharma, A Quintero, D Dreidax, S Jansky, YG Park, ... Nature Cancer 2 (1), 114-128, 2021 | 118 | 2021 |
MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation A Shostak, B Ruppert, N Ha, P Bruns, UH Toprak, R Eils, M Schlesner, ... Nature communications 7 (1), 11807, 2016 | 102 | 2016 |
Mutational patterns and regulatory networks in epigenetic subgroups of meningioma N Paramasivam, D Hübschmann, UH Toprak, N Ishaque, M Neidert, ... Acta neuropathologica 138, 295-308, 2019 | 82 | 2019 |
The genomic and transcriptional landscape of primary central nervous system lymphoma J Radke, N Ishaque, R Koll, Z Gu, E Schumann, L Sieverling, S Uhrig, ... Nature Communications 13 (1), 2558, 2022 | 75 | 2022 |
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome SA Hartlieb, L Sieverling, M Nadler-Holly, M Ziehm, UH Toprak, ... Nature communications 12 (1), 1269, 2021 | 70 | 2021 |
IG-MYC+ neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas R Wagener, C Lopez, K Kleinheinz, J Bausinger, SM Aukema, I Nagel, ... Blood, The Journal of the American Society of Hematology 132 (21), 2280-2285, 2018 | 63 | 2018 |
Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma SL George, F Lorenzi, D King, S Hartlieb, J Campbell, H Pemberton, ... EBioMedicine 59, 2020 | 55 | 2020 |
Modulation of the chromatin phosphoproteome by the Haspin protein kinase A Maiolica, M de Medina-Redondo, EM Schoof, A Chaikuad, F Villa, ... Molecular & cellular proteomics 13 (7), 1724-1740, 2014 | 55 | 2014 |
Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas D Hübschmann, K Kleinheinz, R Wagener, SH Bernhart, C López, ... Leukemia 35 (7), 2002-2016, 2021 | 53 | 2021 |
Globally altered epigenetic landscape and delayed osteogenic differentiation in H3. 3-G34W-mutant giant cell tumor of bone P Lutsik, A Baude, D Mancarella, S Öz, A Kühn, R Toth, J Hey, UH Toprak, ... Nature communications 11 (1), 5414, 2020 | 44 | 2020 |
FOXR2 stabilizes MYCN protein and identifies non–MYCN-amplified neuroblastoma patients with unfavorable outcome F Schmitt-Hoffner, S van Rijn, UH Toprak, M Mauermann, F Rosemann, ... Journal of Clinical Oncology 39 (29), 3217, 2021 | 30 | 2021 |